Fcγ receptor IIa polymorphism in Caucasian patients with systemic lupus erythematosus: Association with clinical symptoms

Arthritis and Rheumatism

Volumn 41, Issue 7, 1998, Pages 1181-1189

  Manger, Karin ^a   Repp, Roland ^a   Spriewald, Bernd M ^a   Rascu, Astrid ^a   Geiger, Anja ^a   Wassmuth, Ralf ^a   Westerdaal, Nomdo A C ^b   Wentz, Bernhard ^a   Manger, Bernhard ^a   Kalden, Joachim R ^a   Van De Winkel, Jan G J ^b  

^a UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^b UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINUCLEAR ANTIBODY; FC RECEPTOR; IMMUNOGLOBULIN G2; IMMUNOGLOBULIN G3; LUPUS ANTICOAGULANT; RIBONUCLEOPROTEIN ANTIBODY; FC GAMMA RECEPTOR IIA; HLA DR ANTIGEN; LEUKOCYTE ANTIGEN;

ADOLESCENT; ADULT; AGED; ALLELE; ANTIGEN ANTIBODY COMPLEX; ARTHRITIS; ARTICLE; CAUCASIAN; CLINICAL FEATURE; CONTROLLED STUDY; CRYOGLOBULINEMIA; FEMALE; GENETIC POLYMORPHISM; GENOTYPE; HAPLOTYPE; HEMOLYTIC ANEMIA; HLA SYSTEM; HUMAN; HYPOCOMPLEMENTEMIA; LYMPHADENITIS; MAJOR CLINICAL STUDY; MALE; NEPHRITIS; PRIORITY JOURNAL; PROTEINURIA; SCHOOL CHILD; SJOEGREN SYNDROME; SYSTEMIC LUPUS ERYTHEMATOSUS; CHILD; GENETICS; HEMATOLOGIC DISEASE; IMMUNOLOGY; IMMUNOPATHOLOGY; MIDDLE AGED; ONSET AGE;

ADOLESCENT; ADULT; AGE OF ONSET; AGED; ALLELES; ANTIGENS, CD; CHILD; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HEMATOLOGIC DISEASES; HLA-DR ANTIGENS; HUMANS; IMMUNE SYSTEM DISEASES; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RECEPTORS, IGG;

EID: 0031596490     PISSN: 00043591     EISSN: None     Source Type: Journal    
DOI: 10.1002/1529-0131(199807)41:7<1181::AID-ART6>3.0.CO;2-C     Document Type: Article

References (41)

1. Fronek Z, Timmerman LA, Alper CA, Hahn BH, Kalunian K, Peterlin BM, et al. Major histocompatibility complex genes and susceptibility to systemic lupus erythematosus. Arthritis Rheum 1990;33:1542-53.
2. Hartung K, Baur MP, Coldeway R, Fricke M, Kalden JR, Lakomek HJ, et al, and the members of the SLE Study Group. Major histocompatibility complex haplotypes and complement C4 alleles in systemic lupus erythematosus: results of a multicenter study. J Clin Invest 1992;90:1346-51.
3. Davies KAE, Petes AM, Beynon HLC, Walport MJ. Immune complex processing in patients with systemic lupus erythematosus. J Clin Invest 1992;90:2075-83.
4. Löw A, Hotze A, Krapf FD, Schranz W, Manger B, Mahlstedt J, et al. The nonspecific clearance function of the reticuloendothelial system in patients with immune complex mediated diseases before and after therapeutic plasmapheresis. Rheumatol Int 1985;5:69-72.
5. Boros P, Muryoi T, Spiera H, Bona C, Unkeless JC. Autoantibodies directed against different classes of FcγR are found in sera of autoimmune patients. J Immunol 1993;5:218-24.
6. Parren PWHI, Warmerdam PAM, Boeije LCM, Arts J, Westerdaal NAC, Vlug A, et al. On the interaction of IgG subclasses with the low affinity FcγRIIa (CD32) on human monocytes, neutrophils, and platelets. J Clin Invest 1992;90:1537-46.
7. Frank MM, Hamburger MI, Lawley TJ, Kimberly RP, Plotz PH. Defective reticuloendothelial system Fc-receptor function in systemic lupus erythematosus. N Engl J Med 1979;300:518-23.
8. Hamburger MI, Lawley TJ, Kimberly RP, Plotz, PH, Frank MM. A serial study of splenic reticuloendothelial system Fc receptor functional activity in systemic lupus erythematosus. Arthritis Rheum 1982;25:48-54.
9. Salmon JE, Kimberly RP, Gibofsky A, Fotino M. Defective mononuclear phagocyte function in systemic lupus erythematosus: dissociation of Fc receptor-ligand binding and internalization J Immunol 1984;133:2525-31.
10. Van de Winkel JGJ, Capel PJA. Human IgG Fc receptor heterogeneity: molecular aspects and clinical implications. Immunol Today 1993;2:215-21.
11. Rascu A, Repp R, Westerdaal NAC, Kalden J, van de Winkel JGJ. Clinical relevance of human Fcγ receptor polymorphisms. Ann N Y Acad Sci 1997;815:282-95.
12. Van de Winkel JGJ, Capel PJA. Human IgG Fc receptors. Austin (TX): RG Landes Company; 1996.
13. Warmerdam PAM, van de Winkel JGJ, Vlug A, Westerdaal NAC, Capel PJA. A single amino acid in the second Ig-like domain of the human Fcγ receptor II is critical for human IgG2 binding. J Immunol 1991;27:1338-43.
14. Salmon JE, Millard S, Schachter LA, Arnett FC, Ginzler EM, Gourley MF, et al. FcγRIIa alleles are heritable risk factors for lupus nephritis in African Americans. J Clin Invest 1996;97:1348-54.
15. Duits AJ, Bootsma H, Derksen RHWM. Spronk PE, Kater L, Kallenberg CGM, et al. Skewed distribution of IgG Fc receptor IIa (CD32) polymorphism is associated with renal disease in systemic lupus erythematosus patients. Arthritis Rheum 1995;38:1832-6.
16. Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum 1982;25:1271-7.
17. Osborne JM, Chacko GW, Brandt JT, Anderson CL. Ethnic variation in frequency of an allelic polymorphism of human FcγRIIa determined with allele specific oligonucleotide probes. J Immunol Methods 1994;173:207-17.
18. Looney RJ, Abraham GN, Anderson CL. Human monocytes and U937 cells bear two distinct Fc receptors for IgG. J Immunol 1986;136:1641-7.
19. Zipf TF, Lauzon GJ, Longenecker BMA. A monoclonal antibody detecting a 39,000 MW molecule that is present on B lymphocytes and chronic lymphocytic leukemia cells but is rare on acute lymphocytic leukemia blasts. J Immunol 1983;131:3064-72.
20. Gosselin EJ, Brown CL, Anderson CL, Zipf TF, Guyre PM. The monoclonal antibody 41H16 detects the Leu4 responder form of human FcγRII. J Immunol 1990;24:1817-22.
21. Bein G, Glaser R, Kirchner H. Rapid HLA-DRB1 genotyping by nested PCR amplification. Tissue Antigens 1992;39:68-73.
22. Nevinny-Stickel C, Hinzpeter M, Andreas A, Albert ED. Non-radioactive oligotyping for HLA-DR1-DRw10 using polymerase chain reaction, digoxigenin-labelled oligonucleotides and chemiluminescence detection. Eur J Immunogenet 1991;18:323-32.
23. Tiercy JM, Goumaz C, Mach B, Jeannet M. Application of HLA-DR oligotyping to 110 kidney transplant patients with doubtful serological typing. Transplantation 1991;1:1100-14.
24. Bugawan TL, Erlich HA. Rapid typing of HLA-DQB1 DNA polymorphism using non radioactive oligonucleotide probes and amplified DNA. Immunogenetics 1991;33:163-70.
25. Bodmer JG, Marsh SGE, Albert ED, Bodmer WF, Bontrop RE, Charron D, et al. Nomenclature for factors of the HLA system, 1996. Hum Immunol 1997;53:98-128.
26. Hahn BH. Systemic lupus erythematosus. In: Fauci AS, Braunwald E, Isselbacher KJ, Wilson JD, Martin JB, Kasper DL, Hauser SL, Longo DL, eds. Harrison's principles of internal medicine. 14th ed. New York: McGraw-Hill Co, 1998. p. 1876.
27. Vitali C, Bencivelli W, Isenberg DA, Smolen JS, Snaith ML, Sciuto M, et al. and the European Consensus Study Group for Disease Activity in SLE. Disease activity in systemic lupus erythematosus: report of the Consensus Study Group of the European Workshop for Rheumatology Research. II. Identification of the variables indicative of disease activity and their use in the development of an activity score. Clin Exp Rheumatol 1992;10:541-7.
28. Bilar J III, Mosteller F. Medical uses of statistics. Waltham, MA: NEJM Books; 1986.
29. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958;53:457-9.
30. Cox DR, Oakes D. Analysis of survival data. New York: Chapman and Hall; 1984.
31. Lander ES, Schork NJ. Genetic dissection of complex traits. Science 1994;265:2037-48.
32. Botto M, Theodoridis E, Thompson EM, Beyon HL, Briggs D, Isenberg DA, et al. FcγRIIa polymorphism in systemic lupus erythematosus (SLE): no association with disease. Clin Exp Immunol 1996;104:264-8.
33. Ginzler EM, Diamond HS, Weiner M, Schlesinger M, Fries JF, Wasner C, et al. A multicenter study of outcome in systemic lupus erythematosus. I. Entry variables as predictors of prognosis. Arthritis Rheum 1982;25:601-11.
34. Nossent HC, Henzen-Logmans SC, Vroom TM, Berden JHM, Swaak TJG. Contribution of renal biopsy data in predicting outcome in lupus nephritis: analysis of 116 patients. Arthritis Rheum 1990;33:970-7.
35. Bredius RG, Fijen CA, De Haas M. Role of neutrophil FcγRIIa (CD32) and FcγRIIIb (CD16) polymorphic forms in phagocytosis of human IgG1-and IgG3-opsonized bacteria and erythrocytes. Immunology 1994;83:624-30.
36. Winkler TH, Henschel TA, Kaliesa I, Baenkler HW, Skvaril F, Kalden JR. Constant isotype pattern of anti-dsDNA antibodies in patients with systemic lupus erythematosus. Clin Exp Immunol 1988;72:434-9.
37. Bonfa E, Chu JL, Brot N, Elkon K. Lupus antiribosomal antibodies show limited heterogeneity and are predominantly of the IgG1 and IgG2 subclasses. Clin Immunol Immunopathol 1987;45:129-38.
38. Siegert C, Daha M, Westedt ML, van der Voort E, Breedveld F. IgG autoantibodies against C1q are correlated with nephritis, hypocomplementemia, and dsDNA antibodies in systemic lupus erythematosus. J Rheumatol 1991;18:230-4.
39. Prada AE, Strife CF. IgG subclass restriction of autoantibody to solid-phase C1q in membranoproliferative and lupus glomerulonephritis. Clin Immunol Immunopathol 1992;63:84-8.
40. Rubin RL, Tang FL, Chan EKL, Rollard KM, Tsay G, Tan EM. IgG subclasses of autoantibodies in systemic lupus erythematosus, Sjögren's syndrome and drug-induced autoimmunity. J Immunol 1986;137:2528-34.
41. Tsao BP, Cantor RM, Kenneth CK, Chen C, Badhsha H, Singh R, et al. Evidence for linkage of a candidate chromosome 1 region to human systemic lupus erythematosus. J Clin Invest 1997;99:725-31.