Review: Radiation-related brain damage and growth retardation among the prenatally exposed atomic bomb survivors

International Journal of Radiation Biology

Volumn 74, Issue 2, 1998, Pages 159-171

  Otake, M ^a,b   Schull, W J ^c  

^a OKAYAMA UNIVERSITY   (Japan)

^b RADIATION EFFECTS RESEARCH FOUNDATION   (Japan)

^c UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMIC BOMB; ATOMIC BOMB SURVIVOR; BRAIN INJURY; FOLLOW UP; GROWTH RETARDATION; HUMAN; INCIDENCE; INTELLIGENCE QUOTIENT; JAPAN; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; RADIATION INJURY; REVIEW; SEIZURE; ATOMIC WARFARE; BODY HEIGHT; BRAIN; CONGENITAL MALFORMATION; FEMALE; GROWTH; HEAD; INTELLIGENCE TEST; MENTAL DEFICIENCY; PREGNANCY; PRENATAL EXPOSURE; RADIATION EXPOSURE; RADIOMETRY; STATISTICS;

ABNORMALITIES, RADIATION-INDUCED; BODY HEIGHT; BRAIN; FEMALE; GROWTH; HEAD; HUMANS; INTELLIGENCE TESTS; JAPAN; MENTAL RETARDATION; NUCLEAR WARFARE; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RADIOMETRY;

EID: 0031596447     PISSN: 09553002     EISSN: None     Source Type: Journal    
DOI: 10.1080/095530098141555     Document Type: Review

References (41)

1. BARTLETT, M. S., 1937, Some examples of statistical methods in research in agriculture and applied biology. Journal of the Royal Statistical Society, Series B, 4, 137-183.
2. BLOT, W. J., 1975, Review of thirty years study of Hiroshima and Nagasaki atomic bomb survivors. II. Biological effect. C. Growth and development following prenatal and children exposure to atomic radiation. Journal of Radiation Research, 16 (Suppl), 82-88.
3. BLOT, W. J., MORIYAMA, I. M. and MILLER, R. W., 1972, Reproductive potential of males exposed in utero or prepubertally to atomic radiation. ABCC Technical Report 39-72 (Hiroshima Atomic Bomb Casualty Commission).
4. BLOT, W. J., SHIMIZU, Y., KATO, H. and MILLER, R. W., 1975, Frequency of marriage and live birth among survivors prenatally exposed to the atomic bomb. American Journal of Epidemiology, 102, 158-162.
5. DELONGCHAMP, R. R., MABUCHI, K., YOSHIMOTO, Y. and PRESTON, D. L., 1997, Cancer mortality among atomic bomb survivors exposed in utero or as young children, October 1950-May 1992. Radiation Research, 147, 385-395.
6. DOBBING, J., 1984, The pathogenesis of microcephaly with mental retardation. In Effects of Prenatal Irradiation with Special Emphasis on Late Effects European Atomic Energy Community (EUR, 8067EN), pp. 199-212.
7. DOBBING, J. and SANDS, J., 1973, Quantitative growth and development of human brain. Archives of Diseases in Children, 48, 757-767.
8. DUNN, K., YOSHIMARU, H., OTAKE, M. and SCHULL, W. J., 1990, Prenatal exposure to ionizing radiation and subsequent development of seizures. American Journal of Epidemiology, 131, 114-123.
9. FUSHIKI, S., MATSUSHITA, K. and SCHULL, W. J., 1993, Decelerated migration of neocortical neurones in explant culture after exposure to radiation. NeuroReport, 5, 353-356.
10. GOLDSTEIN, L. and MURPHY, D. P., 1929, Etiology of the illhealth in children born after maternal pelvic irradiation. Part 2. Defective children born after post-conception pelvic irradiation. American Journal of Roentgenology, 22, 322-331.
11. HOSHINO, K. and KAMEYAMA, Y., 1988, Development-stay-dependent radiosensitivity of neural cells in the ventricular zone of telencephalon in mouse and rad fetuses. Teratology, 37, 257-262.
12. INTERNATIONAL COMMISSION ON RADIOLOGICAL PRODUCTION, 1969, Radiosensitivity and spatial distribution of dose. Appendix 1: Radiation cataract in man. ICRP Publication 14 (Oxford: Pergamon Press).
13. INTERNATIONAL COMMISSION ON RADIOLOGICAL PRODUCTION, 1986, Developmental effects of irradiation on the brain of the embryo and fetus. ICRP Publication 49 (Oxford: Perganion Press).
14. KAMEYAMA, Y., 1989, High vulnerability of the developing fetal brain to ionizing radiation and hyperthermia. Environmental Medicine, 33, 1-17.
15. KERR, G. D., 1979, Organ dose estimates for the Japanese atomic bomb survivors. Health Physics, 37, 487-508.
16. KONERMANN, G., 1989, Postnatal brain maturation damage induced by prenatal irradiation: modes of effect manifestation and dose-response relations. In Low Dose Radiation: Biological Bases of Risk Assessment, edited by K. F. Baverstock and J. W. Stather (London: Taylor & Francis), pp. 364-376.
17. MILLER, R. W. and MULVIHILL, J. H., 1956, Small head size after atomic irradiation. Teratology, 14, 355-358.
18. MILTON, R. C. and SHOHOJI, T., 1968, Tentative 1965 radiation dose estimation for atomic bomb survivors, Hiroshima and Nagasaki. ABCC Technical Report 1-68 (Hiroshima Atomic Bomb Casualty Commission).
19. MOLE, R. H., 1982, Consequences of pre-natal radiation exposure for post-natal development: a review. International Journal of Radiation Biology, 42, 1-12.
20. OTAKE, M., FUJIKOSHI, Y., SCHULL, W. J. and IZUMI, S., 1993, A longitudinal study of growth and development of stature among prenatally exposed atomic bomb survivors. Radiation Research, 134, 94-101.
21. OTAKE, M. and SCHULL, W. J., 1984, In utero exposure to A-bomb radiation and mental retardation. A reassessment. British Journal of Radiology, 57, 409-414.
22. OTAKE, M. and SCHULL, W. J., 1990, Radiation-related posterior lenticular opacities in Hiroshima and Nagasaki atomic bomb survivors based on the DS86 dosimetry system. Radiation Research, 121, 3-13.
23. OTAKE, M. and SCHULL, W. J., 1993, Radiation-related small head sizes among prenatally exposed A-bomb survivors. International Journal of Radiation Biology, 63, 255-270.
24. OTAKE, M., SCHULL, W. J., FUJIKOSHI, Y. and YOSHIMARU, H., 1988, Effect on school performance of prenatal exposure to ionizing radiation in Hiroshima: a comparison of the T65DR and DS86 dosimetry systems. RERF Technical Report 2-88 (Hiroshima: Radiation Effects Research Foundation).
25. OTAKE, M., SCHULL, W. J. and LEE, S., 1996, Threshold of radiation-related severe mental retardation in prenatally exposed A-bomb survivors: a reanalysis. International Journal of Radiation Biology, 70, 755-763.
26. OTAKE, M., YOSHIMARU, H. and SCHULL, W. J., 1987, Severe mental retardation among the prenatally exposed survivors of atomic bombing of Hiroshima and Nagasaki: a comparison of the T65DR and DS86 dosimetry systems. RERF Technical Report 16-87 (Hiroshima: Radiation Effects Research Foundation).
27. RAKIC, P., 1975, Cell migration and neuronal ectopias in the brain. In Morphogenesis and Malformation of the Face and Brain, edited by D. Bergsma (New York: Alan Liss), pp. 95-129.
28. ROESCH, W. C., 1987, Reassessment of atomic bomb radiation dosimetry in Hiroshima and Nagasaki. RERF Final Report (Hiroshima: Radiation Effects Research Foundation).
29. ROZOVSKI, S. J. and WINICK, M., 1979, Nutrition and cellular growth. In Nutrition: Pre- and Postnatal Development, edited by M. Winick (New York: Plenum Press), pp. 61-102.
30. SCHULL, W. J., 1995, Effects of Atomic Radiation: A Half Century of Studies from Hiroshima and Nagasaki (New York: John Wiley).
31. SCHULL, W. J., NISHITANI, H., HASUO, K., KOBAYASHI, T., GOTO, I. and OTAKE, M., 1991, Brain abnormalities among the mentally retarded prenatally exposed atomic bomb survivors. RERF Technical Report 13-91 (Hiroshima: Radiation Effects Research Foundation).
32. SCHULL, W. J. and OTAKE, M., 1986, Effects on intelligence of prenatal exposure to ionizing radiation. RERF Technical Report 7-86 (Hiroshima: Radiation Effects Research Foundation).
33. SCHULL, W. J., OTAKE, M. and YOSHIMARU, H., 1988, Effect on intelligence test score of prenatal exposure to ionizing radiation in Hiroshima and Nagasaki: a comparison of the T65DR and DS86 dosimetry systems. RERF Technical Report 3-88 (Hiroshima: Radiation Effects Research Foundation).
34. SIENKIEWICZ, Z. J., HAYLOCK R. G. E. and SAUNDERS, R. D., 1994. Prenatal irradiation and spatial memory in mice: investigation of dose-response relationship. International Journal of Radiation Biology, 65, 611-618.
35. TABUCHI, A., HIRAI, T., NAKAGAWA, S., SHIMADA, H. and FUJINO, H., 1967, Clinical findings on in utero exposed microcephalic children. ABCC Technical Report 28-67 (Hiroshima Atomic Bomb Casualty Commission).
36. UNSCEAR (United Nations Scientific Committee on the Effects of Atomic Radiation to the General Assembly), 1986, Genetic and Somatic Effects of Ionizing Radiation (New York: United Nations).
37. WINICK, M., 1976, Malnutrition and Brain Development (New York: Oxford University Press).
38. WOOD, J. W., JOHNSON, K. G. and OMORI, Y., 1967a, In utero exposure to the Hiroshima atomic bomb. An evaluation of head size and mental retardation; 20 years later. Pediatrics, 39, 389-392 (ABCC TR 9-65).
39. WOOD, J. W., JOHNSON, K. G., OMORI, Y., KAWAMOTO, S. and KEEHN, R. J., 1967b, Mental retardation in children exposed in utero, Hiroshima and Nagasaki. American Journal of Public Health, 57, 1381-1390.
40. YOSHIMARU, H., OTAKE, M., SCHULL, W. J. and FUNAMOTO, S., 1995, Further observation on abnormal brain development caused by prenatal exposure to ionizing radiation. International Journal of Radiation Biology, 67, 255-270 (RERF MS 17-94).
41. YOSHIMOTO, Y., KATO, H. and SCHULL, W. J., 1988, Risk of cancer among children exposed in utero to A-bomb radiation, 1950-84. Lancet, ii, 665-669 (RERF TR 4-88).