Histamine H3 receptors - General characterization and their function in the cardiovascular system

Journal of Physiology and Pharmacology

Volumn 49, Issue 2, 1998, Pages 191-211

  Malinowska, B ^a   Godlewski, G ^a   Schlicker, E ^b  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

^b UNIVERSITY OF BONN   (Germany)

Author keywords

Blood vessels; Heart; Histamine H3 receptors; Presynaptic inhibition

Indexed keywords

ALPHA 2 ADRENERGIC RECEPTOR; ALPHA METHYLHISTAMINE; ANTIHISTAMINIC AGENT; CLOBENPROPIT; HISTAMINE; HISTAMINE AGONIST; HISTAMINE H3 RECEPTOR; IMETIT; IMMEPIP; IODOPHENPROPIT; IODOPROXYFAN; LIGAND; NORADRENALIN; RECEPTOR SUBTYPE; THIOPERAMIDE; UNCLASSIFIED DRUG;

BLOOD VESSEL INNERVATION; CARDIOVASCULAR DISEASE; CARDIOVASCULAR SYSTEM; DRUG RECEPTOR BINDING; DRUG STRUCTURE; HEART; HEART RATE; HUMAN; HYPERTENSION; ISCHEMIA; MIGRAINE; NONHUMAN; NORADRENALIN RELEASE; PRESYNAPTIC INHIBITION; RECEPTOR BINDING; REVIEW; TISSUE DISTRIBUTION; ANIMAL; BLOOD PRESSURE; BLOOD VESSEL; HEART MUSCLE; METABOLISM; PHYSIOLOGY; VASCULAR SMOOTH MUSCLE;

ANIMALS; BLOOD PRESSURE; BLOOD VESSELS; CARDIOVASCULAR SYSTEM; HEART RATE; HISTAMINE; HUMANS; MUSCLE, SMOOTH, VASCULAR; MYOCARDIUM; RECEPTORS, HISTAMINE H3;

EID: 0031596166     PISSN: 08675910     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (81)

1. Arrang JM. Pharmacological properties of histamine receptor subtypes. Cell Mol Biol Noisy le grand 1994; 40: 275-281.
2. Hill SJ. Distribution, properties, and functional characteristics of three classes of histamine receptor. Pharmacol Rev 1990; 42: 45-83.
3. Hill SJ, Ganellin CR, Timmerman H et al. International Union of Pharmacology. XIII. Classification of histamine receptors. Pharmacol Rev 1997; 49: 253-278.
4. Schwartz, JC, Arrang JM, Carbarg M, Pollard H, Ruat M. Histaminergic transmission in the mammalian brain. Physiol Rev 1991; 71: 1-51.
5. 3 receptors. Can J Physiol Pharmacol 1995; 73: 558-564.
6. Leurs R, Smit MJ, Timmerman H. Molecular pharmacological aspects of histamine receptors. Pharmacol Ther 1995; 66: 413-463.
7. Ash AS, Schild HO. Receptors mediating some actions of histamine. Br J Pharmacol Chemother 1966; 27: 427-439.
8. 2-receptors. Nature 1972; 236: 385-390.
9. 3) of histamine receptor. Nature 1983; 302: 832-837.
10. 3-receptors. Nature 1987; 327: 117-123.
11. 3-histamine receptor subtypes. Mol Pharmacol 1990; 38: 610-613.
12. 3 receptor heterogeneity. Naunyn-Schmiedeberg's Arch Pharmacol 1994; 350: 375-379.
13. 3 receptor heterogeneity? Naunyn-Schmiedeberg's Arch Pharmacol 1996; 353: 482-488.
14. 3 receptor heterogeneity? J Pharmacol Exp Ther 1996; 276: 1009-1015.
15. 3-receptors in rat cerebral cortical membranes. Br J Pharmacol 1995; 114: 357-362.
16. 35S]GTPγ[S] binding to pertussin toxin. Eur J Pharmacol 1996; 296: 223-225.
17. Nozaki M, Sperelakis N. Pertussin toxin effects on transmitter release from perivascular nerve terminals. Am J Physiol 1989; 256: H455-H459.
18. + + channels. J Pharmacol Exp Ther 1994; 269: 221-229.
19. ++ channels. J Pharmacol Exp Ther 1994; 270: 788-794.
20. + ions, G protein and adenylate cyclase. Naunyn-Schmiedebrg's Arch Pharmacol 1994; 350: 34-41.
21. 3 receptor binding sites in rat brain membranes: modulation by guanine nucleotides and divalent cations. Eur J Pharmacol 1990; 188: 219-227.
22. 2-autoreceptors. Naunyn-Schmiedeberg's Arch Pharmacol 1991; 343: R94.
23. 3-receptor ligands on various biochemical indices of histaminergic neuron activity in rat brain. Eur J Pharmacol 1989; 164: 1-11.
24. 3 receptor negatively coupled to phosphoinositide turnover in the human gastric cell line HTG1. J Biol Chem 1992; 267: 25315-25320.
25. 3 heteroreceptors in the rat dentate gyrus. Abstr Soc Neurosci 1997; 23: 357.
26. + channels to hyperpolarize magnocellular histaminergic neurons of rat posterior hypothalamus. Abstr Soc Neurosci 1991; 17: 409.
27. 3 heteroreceptors. Fundam Clin Pharmacol 1994; 8: 128-137.
28. 3-receptor antagonists. Drugs Future 1996; 21: 507-520.
29. 3 receptors and gastrointestinal functions. Digs Dis Sci 1995; 40: 2052-2063.
30. 3H-choline release in the isolated guinea-pig pancreas. Biog Amines 1997; 13: 425-439.
31. 3-receptors on cholinergic nerves in human airways. Eur J Pharmacol 1989; 163: 383-386.
32. 3-receptors inhibit cholinergic neurotransmission in guinea-pig airways. Br J Pharmacol 1989; 97: 13-15.
33. 3-receptors modulate nonadrenergic noncholinergic neural bronchoconstriction in guinea-pig in vivo. Eur J Pharmacol 1989; 174: 49-55.
34. 3-receptors in the regulation of anaphylactic histamine release from isolated rat peritoneal mast cells. Jpn J Pharmacol 1994; 66: 173-180.
35. 3-receptor modulation in rat lung and spleen. Clin Sci Colch 1994; 87: 151-163.
36. Matsubara T, Moskowitz MA, Huang Z. UK-14,304, R(-)-α-methyl-histamine and SMS 201-995 block plasma protein leakage within dura mater by prejunctional mechanisms. Eur J Pharmacol 1992; 224: 145-150.
37. 3) of histamine receptors on perivascular nerve terminals. Nature 1987; 327: 158-160.
38. 3 receptors. Naunyn-Schmiedeberg's Arch Pharmacol 1992; 346: 46-50.
39. 3 receptor-mediated inhibition of noradrenaline release in pig retina discs. Naunyn-Schmiedeberg's Arch Pharmacol 1990; 342: 497-501.
40. 3 vasodilator mechanisms in the guinea pig ileum. Gastroenterology 1995; 108: 712-718.
41. 3 receptors in isolated guinea pig pulmonary artery and ileum. Eur J Pharmacol 1995; 294: 329-335.
42. 3 receptors in the tail artery from normotensive and spontaneously hypertensive rats. J Cardiovasc Pharmacol 1997; 29: 801-807.
43. B receptors but not affected by histamine. Br J Pharmacol 1991; 104: 478-482.
44. 3 receptors on sympathetic nerves of the pithed rat: activation by endogenous histamine and operation in spontaneously hypertensive rats. Naunyn Schmiedeberg's Arch Pharmacol 1997; 355: 261-266.
45. 3 receptor-mediated inhibition of the neurogenic vasopressor response in pithed rats. Eur J Pharmacol 1991; 205: 307-310.
46. 3 agonists on the neurogenic vasopressor response in the pithed rat. Agents Actions 1993; 38: C254-C256.
47. 3-receptors inhibit electrically evoked endogenous noradrenaline overflow in the portal vein of freely moving rats. Naunyn-Schmiedeberg's Arch Pharmacol 1997; 355: 256-260.
48. 3-receptors. Br J Pharmacol 1992; 107: 347-351.
49. 3) agonist is attenuated by an inhibitor of nitric oxide synthesis. J Cardiovasc Pharmacol 1996; 27: 607-613.
50. Hutchison RW, Hey JA. Pharmacological characterization of the inhibitory effect of (R)-α-methylhistamine on sympathetic cardiopressor responses in the pithed guinea-pig. J Auton Pharmacol 1994; 14: 393-402.
51. Maśliński C, Fogel WA. Catabolism of histamine. In: Handbook of experimental pharmacology. B. Uvnäs (ed), Springer 1991, Vol 97, pp. 165-189.
52. Hough LB, Khandelwal JK, Green JP. Inhibition of brain histamine metabolism by metoprine. Biochem Pharmacol 1986; 35: 307-310.
53. Itoh Y, Oishi R, Nishibori M, Saeki K. Characterization of histamine release from the rat hypothalamus as measured by in vivo microdialysis. J Neurochem 1991; 56: 769-774.
54. 3 receptor model. Naunyn-Schmiedeberg's Arch Pharmacol 1993; 348: 498-503.
55. Nichol CA, Cavallito JC, Wooley JL, Sigel CW. Lipid-solubile diaminopyrimidine inhibitors of dihydrofolate reductase. Cancer Treat Rep 1977; 61: 559-564.
56. Campos HA, Acuňa Y, Magaldi L, Israel A. Alpha-fluoromethylhistidine, an inhibitor of histamine biosynthesis, causes arterial hypertension. Naunyn-Schmiedeberg's Arch Pharmacol 1996; 354: 627-632.
57. 3 receptor activation. Eur J Pharmacol 1994; 259: 211-214.
58. 2-adrenoceptors on noradrenergic terminals in mouse and rat brain cortex. Naunyn-Schmiedeberg's Arch Pharmacol 1992; 345: 639-646.
59. 3 receptors. Naunyn-Schmiedeberg's Arch Pharmacol 1989; 340: 633-638.
60. 3 receptors in the modulation of noradrenaline release from rat spinal cord slices. Eur J Pharmacol 1995; 287: 127-133.
61. 3-receptors inhibit sympathetic neurotransmission in guinea pig myocardium. Eur J Pharmacol 1991; 204: 311-314.
62. 3 receptors in the anaesthetized rat. Naunyn-Schmiedeberg's Arch Pharmacol 1995; 351: 569-575.
63. 3 receptors in the pithed rat. Naunyn-Schmiedeberg's Arch Pharmacol 1993; 347: 55-60.
64. 3 agonist relaxes rabbit middle cerebral artery, in vitro. Eur J Pharmacol 1988; 150: 393-396.
65. 3 agonist is reduced by inhibitors of nitric oxide and prostacyclin synthesis. Br J Pharmacol 1992; 105: 103-106.
66. 3 receptor-mediated endothelium-dependent relaxation in isolated rat aorta. Mediators of Inflammation 1995; 4: 217-221.
67. + - ATP-ase. Mediators of Inflammation 1996; 5: 69-74.
68. 2+ current via GTP hydrolysis in rabbit saphenous artery. J Physiol-Lond 1992; 448: 133-152.
69. 3-receptors in myocardial ischemia: their role as regulators of exocytotic norepinephrine release. J Pharmacol Exp Ther 1994; 271: 1259-1266.
70. 2-adrenoceptors. Circ Res 1996; 78: 475-481.
71. 3-receptors in the human heart. Circ Res 1995; 77: 206-210
72. Fuder H, Ries P, Schwarz P. Histamine and serotonin released from the rat perfused heart by compound 48/80 or by allergen challenge influence noradrenaline or acetylcholine exocytotic release. Fundam Clin Pharmacol 1994; 8: 477-490.
73. 3 agonist decreases arterial blood pressure in the guinea-pig. J Pharm Pharmacol 1993; 45: 929-931.
74. 3 receptors by R-α-methylhistamine in the guinea pig. Gen Pharmacol 1996; 27: 1001-1007.
75. 3 receptors in conscious guinea pigs. Eur J Pharmacol 1991; 209: 141-142.
76. 3 receptors. Eur J Pharmacol 1994; 251: 43-51.
77. 3 receptor-mediated effects in the cardiovascular system of pithed rats. In: Funktionsanalyse biologischer Systeme. J Grote, C Stick (eds). Stuttgart, Gustav Fischer Verlag, 1996. Vol. 25, pp. 83-89.
78. 2-adrenoceptor-mediated facilitation of the neurogenic vasopressor response in the pithed rat. Naunyn-Schmiedeberg's Arch Pharmacol 1988; 338: 536-542.
79. B receptor-mediated inhibition of the neurogenic vasopressor response in the pithed rat. Br J Pharmacol 1990; 100: 365-369.
80. 1 receptor-mediated inhibition of the neurogenic vasopressor response in the pithed rat. Naunyn-Schmiedeberg's Arch Pharmacol 1997; 356: 197-202.
81. 3 receptor-mediated inhibition of the neurogenic vasopressor response in pithed rats. Eur J Pharmacol 1994; 259: 315-319.