Effects of the AT1 antagonist HR 720 in comparison to losartan on stimulated sympathetic outflow, blood pressure, and heart rate in pithed spontaneously hypertensive rats

Kidney and Blood Pressure Research

Volumn 21, Issue 1, 1998, Pages 29-35

  Hauser W ^a   Dendorfer, A ^a   Nguyen, T ^a   Dominiak, P ^a  

^a UNIVERSITY OF LÜBECK   (Germany)

Author keywords

Angiotensin II; AT1 antagonists; Catecholamine release; HR 720; Losartan; Spontaneously hypertensive rats

Indexed keywords

2 BUTYL 4 METHYLTHIO 1 [[2' [[[(PROPYLAMINO)CARBONYL]AMINO]SULFONYL][1,1' BIPHENYL] 4 YL]METHYL] 1H IMIDAZOLE 5 CARBOXYLIC ACID; ADRENALIN; ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; ANGIOTENSIN II ANTAGONIST; ANGIOTENSIN RECEPTOR ANTAGONIST; CATECHOLAMINE; LOSARTAN; NORADRENALIN; UNCLASSIFIED DRUG; ANGIOTENSIN I; ANGIOTENSIN II; ANTIHYPERTENSIVE AGENT; BIPHENYL DERIVATIVE; FONSARTAN; IMIDAZOLE DERIVATIVE;

ADRENALIN RELEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD PRESSURE; CATECHOLAMINE RELEASE; CONTROLLED STUDY; DOSE RESPONSE; DRUG POTENCY; HEART RATE; HYPERTENSION; INTRAVENOUS DRUG ADMINISTRATION; ISOLATED ORGAN; MALE; NONHUMAN; NORADRENALIN RELEASE; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; SYMPATHETIC FUNCTION; ADRENERGIC SYSTEM; ANIMAL; BLOOD; COMPARATIVE STUDY; DECEREBRATION; DRUG ANTAGONISM; DRUG EFFECT; ELECTROSTIMULATION; HEMODYNAMICS; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANGIOTENSIN I; ANGIOTENSIN II; ANIMALS; ANTIHYPERTENSIVE AGENTS; BIPHENYL COMPOUNDS; BLOOD PRESSURE; CATECHOLAMINES; DECEREBRATE STATE; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; HEART RATE; HEMODYNAMIC PROCESSES; HYPERTENSION; IMIDAZOLES; LOSARTAN; MALE; RATS; RATS, INBRED SHR; SYMPATHETIC NERVOUS SYSTEM;

EID: 0031595943     PISSN: 14204096     EISSN: None     Source Type: Journal    
DOI: 10.1159/000025840     Document Type: Article

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