Residential 222Rn exposure and lung cancer: Testing the linear no- threshold theory with ecologic data

Health Physics

Volumn 75, Issue 1, 1998, Pages 11-17

  Smith, Brian J ^b   Field, R William ^a   Lynch, Charles F ^a  

^a UNIVERSITY OF IOWA   (United States)

^b NONE

Author keywords

222Rn; Cancer; Epidemiology; Lungs, human

Indexed keywords

RADON 222; RADON;

CANCER INCIDENCE; CANCER MORTALITY; DATA ANALYSIS; ECOLOGY; HUMAN; LUNG CANCER; PRIORITY JOURNAL; RADIATION CARCINOGENESIS; RADIATION EXPOSURE; REGRESSION ANALYSIS; REVIEW; SMOKING; THEORY; AIR POLLUTANT; CASE CONTROL STUDY; COHORT ANALYSIS; LUNG TUMOR; MORTALITY; NOTE; RADIATION INJURY; STATISTICAL MODEL; UNITED STATES;

AIR POLLUTANTS, RADIOACTIVE; CASE-CONTROL STUDIES; COHORT STUDIES; HUMANS; IOWA; LUNG NEOPLASMS; MODELS, STATISTICAL; NEOPLASMS, RADIATION-INDUCED; RADON; REGRESSION ANALYSIS; SMOKING;

EID: 0031595373     PISSN: 00179078     EISSN: None     Source Type: Journal    
DOI: 10.1097/00004032-199807000-00002     Document Type: Review

References (25)

1. Brenner, H.; Savitz, D. A.; Jockel, K. H.; Greenland, S. Effects of nondifferential exposure misclassification in ecologic studies. Am. J. Epidemiol. 135:85-95; 1992.
2. Cohen, B. L. A test of the linear no-threshold theory of radiation carcinogenesis. Environmental Res. 53:193-220; 1990.
3. Cohen, B. L. Test of the linear no-threshold theory of radiation carcinogenesis for inhaled radon decay products. Health Phys. 68:157-174; 1995.
4. Cohen, B. L. Problems in the radon vs. lung cancer test of the linear no-threshold theory and a procedure for resolving them. Health Phys. 72:623-628; 1997a.
5. Cohen, B. L. Response to D. J. Strom. Health Phys. 72:489-490; 1997b.
6. Cohen, B. L.; Colditz, G. A. Tests of the linear no-threshold theory for lung cancer induced by exposure to radon. Environmental Res. 64:65-89; 1994.
7. Field, R. W.; Steck, D. J.; Lynch, C. F.; Brus, C. P.; Neuberger, J. S.; Kross, B. C. Residential radon-222 exposure and lung cancer: exposure assessment methodology. J. Exposure Analysis and Environmental Epidemiol. 6:181-195; 1996.
8. Greenland, S. Divergent biases in ecologic and individual-level studies. Statistics in Med. 11:1209-23; 1992.
9. Greenland, S.; Robins, J. Invited commentary: ecologic studies-biases, misconceptions, and counterexamples. Am. J. Epidemiol. 139:747-760; 1994.
10. Karnell, L. H.; Kelly, S. L.; Olson, D. B.; Mckeen, K. M.; Platz, C. E.; Lynch, C. F. Cancer in Iowa: 1973-1992. State Health Registry of Iowa. Iowa City: The University of Iowa Press; 1995.
11. Lubin, J. H.; Samet, J. M.; Weinberg, C. Design issues in epidemiologic studies of indoor exposure to radon and risk of lung cancer. Health Phys. 59:807-817; 1990.
12. Lubin, J. H. On the discrepancy between epidemiologic studies in individuals of lung cancer and residential radon and Cohen's ecologic regression. Health Phys. 75:4-10; 1998.
13. Moeller, D. W.; Underhill, D. W. Final report on the study of the effects of building materials on population dose equivalent. Boston, MA: School of Public Health, Harvard University; 1976.
14. Moolgavkar, S. H.; Luebeck, E. G.; Krewski, D.; Zielinski, J. M. Radon, cigarette smoke, and lung cancer: a reanalysis of the Colorado Plateau uranium miners' data. Epidemiol. 4:204-217; 1993.
15. Morgenstern, H. Uses of ecologic analysis in epidemiology research. Am. J. Public Health 72:1336-1344; 1982.
16. National Academy of Sciences. Committee on Biological Effects of Ionizing Radiation. Health risks of radon and other internally deposited alpha emitters (BEIR IV). Washington, DC: National Academy Press; 1988.
17. Neuberger, J. S. Residential radon exposure and lung cancer: an overview of published studies. Cancer Detection and Prevention 15:435-441; 1991.
18. Neuberger, J. S.; Lynch, C. F.; Kross, B. C.; Field, R. W.; Woolson, R. F. Residential radon exposure and lung cancer: evidence of an urban factor in Iowa. Health Phys. 66:263-269; 1994.
19. Oakley, D. T. Natural radiation exposure in the United States. Washington, DC: U.S. EPA; ORP/SID 72-1; 1972.
20. Piantadosi, S. Invited commentary: ecologic biases. Am. J. Epidemiol. 139:761-764; 1994.
21. Piantadosi, S.; Byar, D. P.; Green, S. B. The ecological fallacy. Am. J. Epidemiol. 127:893-904; 1988.
22. Puntoni, R.; Toninelli, F.; Zhankui, L.; Bonassi, S. Mathematical modelling in risk/exposure of tobacco related lung cancer. Carcinogenesis 16:1465-1471; 1995.
23. Riggan, W. B.; Van Bruggen, J.; Acquavella, J. F.; Beaubier, J.; Mason, T. J. U.S. cancer mortality and trends, 1950-1979. Washington, DC: U.S. Government Printing Office; National Cancer Institute, United States Environmental Protection Agency, EPA-600/1-83-015; 1983.
24. Stidley, C. A.; Samet, J. M. A review of ecologic studies of lung cancer and indoor radon. Health Phys. 65:234-251; 1993.
25. Walter, S. D. The ecologic method in the study of environmental health. II. Methodologic issues and feasibility. Environmental Health Perspectives 94:67-73; 1991.