N1,N12-bis(ethyl)spermine effect on growth of cis- diamminedichloroplatinum(II)-sensitive and -resistant human ovarian-carcinoma cell lines

International Journal of Cancer

Volumn 78, Issue 1, 1998, Pages 33-40

  Marverti, Gaetano ^a,b   Piccinini, Giorgio ^a   Ghiaroni, Stefania ^a   Barbieri, Daniela ^a   Quaglino, Daniela ^a   Moruzzi, Maria Stella ^a  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b Istituto di Chimica Biologica   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACYLTRANSFERASE; CISPLATIN; N1,N12 DIETHYLSPERMINE; POLYAMINE; ANTINEOPLASTIC AGENT; DIAMINE ACETYLTRANSFERASE; DIAMINE N-ACETYLTRANSFERASE; DRUG DERIVATIVE; N(1),N(11) DIETHYLNORSPERMINE; N(1),N(11)-DIETHYLNORSPERMINE; SPERMINE;

ARTICLE; CELL CYCLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG MECHANISM; DRUG POTENTIATION; FEMALE; HUMAN; HUMAN CELL; MEMBRANE POTENTIAL; MITOCHONDRION; OVARY CARCINOMA; POLYAMINE SYNTHESIS; PRIORITY JOURNAL; CELL CULTURE; DRUG EFFECT; DRUG INTERACTION; DRUG RESISTANCE; ENZYME INDUCTION; METABOLISM; OVARY TUMOR; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY;

ACETYLTRANSFERASES; ANTINEOPLASTIC AGENTS; CISPLATIN; DRUG INTERACTIONS; DRUG RESISTANCE, NEOPLASM; ENZYME INDUCTION; FEMALE; HUMANS; MITOCHONDRIA; OVARIAN NEOPLASMS; SPERMINE; TUMOR CELLS, CULTURED;

EID: 0031595242     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19980925)78:1<33::AID-IJC7>3.0.CO;2-Y     Document Type: Article

References (40)

1. 12-bis(ethyl)spermine. Biochem. J., 291, 131-137 (1993).
2. ANDREWS, P.A. and ALBRIGHT, K.D., Mitochondrial defects in cisdiamminedichloroplatinum(II)-resistant human ovarian-carcinoma cells. Cancer Res., 52, 1895-1901 (1992).
3. ANDREWS, P.A. and HOWELL, S.B., Cellular pharmacology of cisplatin: perspectives on mechanisms of acquired resistance. Cancer Cells, 2, 35-43 (1990).
4. BASU, H.S., FEUERSTEIN, B.G., DEEN, D.F., LUBICH, W.P., BERGERON, R.J., SAMEJIMA, K. and MARTON, L.J., Correlation between the effects of polyamine analogues on DNA conformation and cell growth. Cancer Res., 49, 5591-5597 (1989).
5. BASU, H.S., SCHWIETERT, H.C., FEUERSTEIN, B.G., and MARTON, L.J., Effects of variation in the structure of spermine on the association with DNA and the induction of DNA conformational chances. Biochem. J., 269, 329-334 (1990).
6. 14-bis-(ethyl)-homospermine (BE 4-4-4) on the growth of U-251 MG and SF-188 human brain-tumor cells. Int. J. Cancer, 48, 873-878 (1991).
7. BASU, H.S., STURKENBOOM, M.C.J., DELCROS, J.G., CSOKAN, P.P., SZOLLOSI, J., FEUERSTEIN, B.G., and MARTON, L.J., Effect of polyamine depletion on chromatin structure in U-87MG brain tumour cells. Biochem. J., 282, 723-727 (1992).
8. BAZZANI, C., GENEDANI, S., TAGLIAVINI, S., PICCININI, G. and BERTOLINI, A., Treatment with polyamine-synthesis inhibitors reduces the positive ionotropic effect of ouabain, noradrenaline and calcium. Pharm. Res. Commun., 20, 23-35 (1988).
9. BERNACKI, R.J., BERGERON, R.J. and PORTER, C.W., Anti-tumor activity of N,N′-bis(ethyl)spermine homologues against human MALME-3 melanoma xenografts. Cancer Res., 52, 2424-2430 (1992).
10. BYCZKOWSKY, J.Z., ZECHLINSKI, L. and PORTER, C.W., Inhibition of the bio-energetic functions of isolated rat liver mitochondria by polyamines. Biochem. Pharmacol., 31, 4045-4053 (1982).
11. 1-acetyltransferase in human lung-cancer cells by the bis(ethyl)polyamine analogues. Cancer Res., 49, 3829-3833 (1989).
12. 12-bis(ethyl)spermine in human cell lines representing the major forms of lung cancer. Cancer Res., 52, 5359-5363 (1992).
13. CHOU, T.C. and TALALAY, P., Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. In: G. Weber (ed.), Advances in enzyme regulation, pp. 27-55, Pergamon Press, New York (1984).
14. DOLBEARE, F., GRATZNER, H., PALLAVICINI, M.G. and GRAY, J.W., Flowcytometric measurement of total DNA content and incorporated bromodeoxyuridine. Proc. nat. Acad. Sci. (Wash.), 80, 5573-5577 (1983).
15. DORHOUT, B., TE VELDE, R.J., FERWERDA, H., KINGMA, A.W., DE HOOG, E. and MUSKIET, F.A., In vivo effects of 4-amidinoindan-1-one 2′-amidinohydrazone (CGP 48664A) and α-difluoromethylornithine (DFMO) on L1210 growth, cell-cycle phase distribution and polyamine content. Int. J. Cancer, 62, 738-742 (1995).
16. EDWARDS, M.L., SNYDER, R.D. and STEMERICK, D.M., Synthesis and DNA-binding properties of polyamine analogues. J. med. Chem., 34, 2414-2420 (1991).
17. 1- acetyltransferase in L6 cells by polyamines and related compounds. Biochem. J., 238, 581-587 (1986).
18. FEUERSTEIN, B.G., BASU, H.S. and MARION, L.J., Theoretical and experimental characterization of polyamine/DNA interactions. Adv. exp. Med. Biol., 250, 517-523 (1988).
19. 12-bis(ethyl)spermine. Europ. J. Biochem., 209, 689-696 (1992).
20. KOZA, R.A. and HERBST, E.J., Deficiencies in DNA replication and cell-cycle progression in polyamine-depleted HeLa cells. Biochem. J., 281, 87-93 (1992).
21. LIBBY, P.R., BERGERON, R.J. and PORTER, C.W., Structure-function correlations of polyamine analog induced increases in spermidine/spermine acetyl-transferase activity. Biochem. Phannacol., 38, 1435-1442 (1989a).
22. 1-acetyl-transferase activity by spermine analogues and their relationship to polyamine depletion and growth inhibition in L1210 cells. Cancer Res., 49, 6226-6231 (1989b).
23. LICHTSTEIN, D., KABACK, H.R. and BLUME, A.J., Use of lipophilic cation for determination of membrane potential in neuroblastoma-glioma hybrid cell suspensions. Proc. nat. Acad. Sci. (Wash.), 76, 650-654 (1979).
24. LOWRY, O.H., ROSEBROUGH, N.J., FARR, A.L. and RANDALL, R.J., Protein measurement with the Folin phenol reagent. J. biol. Chem., 193, 265-275 (1951).
25. MAMONT, P.S., DUCHESNE, M.C., GROVE, J. and BEY, P., Anti-proliferative properties of DL-α-difluoromethylornithine in cultured cells. A consequence of irreversible inhibition of ornithine decarboxylase. Biochem. biophys. Res. Commun., 81, 58-66 (1978).
26. MANN, S.C., ANDREWS, P.A. and HOWELL, S.B., Modulation of cisdiamminedichloroplatinum(II) accumulation and sensitivity by forskolin and 3-isobutil-l-methylxanthine in sensitive and resistant human ovariancarcinoma cells. Int. J. Cancer, 48, 866-872 (1991).
27. MARVERTI, G. and ANDREWS, P.A., Stimulation of cis-diamminedichloroplatinum(II) accumulation by modulation of passive permeability with genistein: an altered response in accumulation-defective resistant cells. Clin. Cancer Res., 2, 991-999 (1996).
28. MARVERTI, G., ANDREWS, P.A., PICCININI, G., GHIARONI, S., BARBIERI, D. and MORUZZI, M.S., Modulation of cis-diamminedichloroplatinum (II) accumulation and cytotoxicity by spermine in sensitive and resistant human ovarian-carcinoma cells. Europ. J. Cancer, 33, 669-675 (1997).
29. MONTI, M.G., PERNECCO, L., MANFREDINI, R., FRASSINETI, C., BARBIERI, D., MARVERTI, G. and GHIARONI, S., Inhibition of cell growth by accumulated spermine is associated with a transient alteration of celt-cycle progression. Life Sci., 58, 2065-2072 (1996).
30. OZOLS, R.F. and YOUNG, R.C., Ovarian cancer. Curr. Probl. Cancer, 11, 57-122 (1987).
31. 12-bis(ethyl)spermine and related compounds on growth and polyamine acetylation, content and excretion in human colon-tumor cells. J. biol. Chem., 264, 11744-11749 (1989).
32. 1-acetyl-transferase using specific anti-serum. J. biol. Chem., 259, 12364-12367 (1984).
33. PHILLIPS, J.E. and CHAFFEE, R.R.J., Restorative effects of spermine on oxidative phosphorylation and respiration in heat-aged mitochondria. Biochem. biophys. Res. Comm., 108, 174-181 (1982).
34. PORTER, C.W., MCMANIS, J., CASERO, R.A. and BERGERON, R.J., The relative abilities of bis(ethyl) derivatives of putrescine. spermidine and spermine to regulate polyamine biosynthesis and inhibit cell growth. Cancer Res., 47, 2821-2825 (1987).
35. SEILER, N., KNODGEN, B. and EISENBEISS, F., Determination of di- and polyamines by high-performance liquid-chromatographic separation of their 5-dimethylaminonaphtalene-l-sulfonyl derivatives. J. Chromatogr., 145, 29-39 (1978).
36. SNYDER, R.D., Polyamine depletion is associated with altered chromatin structure in HeLa cells. Biochem. J., 260, 697-704 (1989)
37. SNYDER, R.D., BEACH, D.C. and LOUDY, D.E., Anti-mitochondrial effects of bisethyl polyamines in mammalian cells. Anticancer Res., 14, 347-356 (1994).
38. TSUCHIYA, H., TOMITA, K., YASUTAKE, H., UEDA, Y., TANAKA, M. and TAKUMA, S., Growth inhibition and differentiation of murine melanoma B16-BL6 cells caused by the combination of cisplatin and caffeine. Jap. J. Cancer Res., 80, 1246-1251.(1989).
39. 12-bis(ethyl)spermine and its relationship to polyamine structure and function. Mol. Pharmacol., 39, 487-494 (1991).
40. ZINKEWICH-PÉOTTI, K. and ANDREWS, P.A., Loss of cis-diamminedichloroplatinum(II) resistance in human ovarian-carcinoma cells selected for rhodamine-123 resistance. Cancer Res., 52, 1902-1906 (1992).