Associations between TGF-β1 receptors in human bone marrow stromal cells

British Journal of Haematology

Volumn 102, Issue 3, 1998, Pages 804-811

  Robledo, Mar M ^a   Ursa, Ma Angeles ^b   Sánchez Madrid, Francisco ^b   Teixidó, Joaquín ^a  

^a CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^b HOSPITAL UNIVERSITARIO DE LA PRINCESA   (Spain)

Author keywords

Bone marrow; Stroma; TGF 1 receptors

Indexed keywords

TRANSFORMING GROWTH FACTOR BETA RECEPTOR; TRANSFORMING GROWTH FACTOR BETA1; CELL SURFACE RECEPTOR; ENG PROTEIN, HUMAN; INTERLEUKIN 1; LEUKOCYTE ANTIGEN; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; BONE MARROW CELL; CYTOKINE PRODUCTION; HUMAN; HUMAN TISSUE; LIGAND BINDING; PRIORITY JOURNAL; RECEPTOR BINDING; REGULATORY MECHANISM; CELL CULTURE; METABOLISM; STROMA CELL;

ANTIGENS, CD; BONE MARROW CELLS; CELLS, CULTURED; HUMANS; INTERLEUKIN-1; RECEPTORS, CELL SURFACE; RECEPTORS, TRANSFORMING GROWTH FACTOR BETA; STROMAL CELLS; VASCULAR CELL ADHESION MOLECULE-1;

EID: 0031595181     PISSN: 00071048     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2141.1998.00820.x     Document Type: Article

References (53)

1. Abboud, S.L. (1993) A bone marrow stromal cell line is a source and target for platelet-derived growth factor. Blood, 81, 2547-2553.
2. Bellón, T., Corbí, A., Lastres, P., Calés, C., Cebrián, M., Vera, S., Chiefetz, S., Letarte, M. & Bernabeu, C. (1993) Identification and expression of two forms of the human transforming growth factor-1-binding protein endoglin with distinct cytoplasmic regions. European Journal of Immunology, 23, 2340-2345.
3. Bühring, H.J., Müller, C.A., Letarte, M., Gougos, A., Saalmüller, A., van Agthoven, A.J. & Busch, F.W. (1991) Endoglin is expressed on a subpopulation of immature erythroid cells of normal human bone marrow. Leukemia, 5, 841-847.
4. Cheifetz, S., Bellón, T., Calés, C., Vera, S., Bernabeu, C., Massagué, J. & Letarte, M. (1992) Endoglin is a component of the transforming growth factor-β receptor system in human endothelial cells. Journal of Biological Chemistry, 267, 19027-19030.
5. Cheifetz, S. & Massagué, J. (1991) Isoform-specific transforming growth factor-β binding proteins with membrane attachments sensitive to phosphatidylinositol-specific phospholipase C. Journal of Biological Chemistry, 266, 20767-20772.
6. Dejana, E., Colella, S., Languino, L.R., Balconi, G., Corbascio, C. & Marchisio, P.C. (1987) Fibrinogen induces adhesion, spreading and microfilament organization of human endothelial cells in vitro. Journal of Cell Biology, 104, 1403-1411.
7. Deryugina, E.I. & Müller-Sieburg, C.E. (1993) Stromal cells in long-term cultures: keys to the elucidation of hematopoietic development? Critical Reviews in Immunology, 13, 115-150.
8. Dorshkind, K. (1990) Regulation of haemopoiesis by bone marrow stromal cells and their products. Annual Review of Immunology, 8, 111-137.
9. Dubois, C.M., Ruscetti, F.W., Palaszynski, E.W., Falk, L.A., Oppenheim, J.J. & Keller, J.R. (1990) Transforming growth factor-β is a potent inhibitor of interleukin 1 (IL-1) receptor expression: proposed mechanism of inhibition of IL-1 action. Journal of Experimental Medicine, 172, 737-744.
10. Dubois, C.M., Ruscetti, F.W., Stankova, J. & Keller, J.R. (1994) Transforming growth factor-β regulates c-kit message stabolity and cell-surface protein expression in hematopoietic progenitors. Blood, 83, 3138-3145.
11. Eaves, C.J., Cashman, J.D., Kay, R.J., Dougherty, G.J., Otsuka, T., Gaboury, L.A., Hogge, D.E., Lansdorp, P.M., Eaves, A.C. & Humphries, R.K. (1991) Mechanisms that regulate the cell cycle status of very primitive hematopoietic cells in long-term human marrow cultures. II. Analysis of positive and negative regulators produced by stromal cells within the adherent layer. Blood, 78, 110-117.
12. Fava, R.A., Casey, T.T., Wilcox, J., Pelton, R.W., Moses, H.L. & Nanney, L.B. (1990) Synthesis of transforming growth factor-β1 by megakaryocytes and its localization to megakaryocyte and platelet α-granules. Blood, 76, 1946-1955.
13. Friedrich, C., Zausch, E., Sugrue, S.P. & Gutiérrez-Ramos, J.C. (1996) Hematopoietic supportive functions of mouse bone marrow and fetal liver microenvironment: dissection of granulocyte, B-lymphocyte, and hematopoietic progenitor support at the stroma cell clone level. Blood, 87, 4596-4606.
14. Gimble, J.M., Hudson, J., Henthorn, J., Hua, X.X. & Burstein, S.A. (1991) Regulation of interleukin 6 expression in murine bone marrow stromal cells. Experimental Hematology, 19, 1055-1060.
15. Gimble, J.M., Pietrangeli, C., Henley, A., Dorheim, M.A., Silver, J., Namen, A., Takeichi, M., Goridis, C. & Kincade, P.W. (1989) Characterization of murine bone marrow and spleen-derived stromal cells: analysis of leucocyte marker and growth factor mRNA transcript levels. Blood, 74, 303-311.
16. Gougos, A. & Letarte, M. (1988) Identification of a human endothelial cell antigen with monoclonal antibody 44G4 produced against a pre-B leukemic cell line. Journal of Immunology, 141, 1925-1933.
17. Gougos, A. & Letarte, M. (1990) Primary structure of endoglin, an RGD-containing glycoprotein of human endothelial cells. Journal of Biological Chemistry, 265, 8361-8364.
18. Heinrich, M.C., Dooley, D.C. & Keeple, W.W. (1995) Tranforming growth factor-β1 inhibits expression of the gene products for steel factor and its receptor (c-kit). Blood, 85, 1769-1780.
19. Hemler, M.E., Sánchez-Madrid, F., Flotte, T.J., Krensky, A.M., Burakoff, S.J., Bhan, A.K., Springer, T.A. & Strominger, J.L. (1984) Glycoproteins of 210,000 and 130,000 M.W. on activated T cells: cell distribution and antigenic relation to components on resting cells and T cell lines. Journal of Immunology, 132, 3011-3018.
20. Hino, M., Tojo, A., Miyazono, K., Miura, Y., Urabe, A. & Takaku, F. (1988) Effects of type β transforming growth factors on haematopoietic progenitor cells. British Journal of Haematology, 70, 143-147.
21. Hurley, R.W., McCarthy, J.B. & Verfaillie, C.M. (1995) Direct adhesion to bone marrow stroma via libronectin receptors inhibits hematopoietic progenitor proliferation. Journal of Clinical Investigation, 96, 511-519.
22. Ignotz, R.A. & Massagué, J. (1986) Transforming growth factor-β stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix. Journal of Biological Chemistry, 261, 4337-4345.
23. Jacobsen, E.S.W., Ruscetti, F.W., Roberts, A.B. & Keller, J.R. (1993) TGF-β is a bidirectional modulator of cytokine receptor expression on murine bone marrow cells. Journal of Immunology, 151, 4534-4544.
24. Jacobsen, F.W., Stokke, T. & Jacobsen, S.E.W. (1995) Transforming growth factor-β potently inhibits the viability-promoting activity of stem cell factor and other cytokinesis and induces apoptosis of primitive murine hematopoietic progenitor cells. Blood, 86, 2957-2966.
25. Keller, J.R., Jacobsen, S.E., Sill, K.T., Ellingsworth, L.R. & Ruscetti, F.W. (1991) Stimulation of granulopoiesis by transforming growth factor β: synergy with granulocyte/macrophage-colony stimulating factor. Proceedings of the National Academy of Sciences of the United States of America, 88, 7190-7194.
26. Keller, J.R., Mantel, C., Sing, G.K., Ellingsworth, L.R., Ruscetti, S.K. & Ruscetti, F.W. (1988) Transforming growth factor β1 selectively regulates early murine hematopoietic progenitors and inhibits the growth of IL-3-dependent cell lines. Journal of Experimental Medicine, 168, 737-750.
27. Kingsley, D.M. (1994) The TGF-β superfamily: new members, new receptors, and new genetic tests of function in different organisms. Trends in Genetics, 10, 16-21.
28. Lastres, P., Bellón, T., Cabañas, C., Sánchez-Madrid, F., Acevedo, A., Gougos, A., Letarte, M. & Bernabeu, C. (1992) Regulated expression on human macrophages of endoglin, an Arg-Gly-Asp-containing surface antigen. European Journal of Immunology, 22, 393-397.
29. Lastres, P., Letamendía, A., Zhang, H., Rius, C., Almendro, N., Raab, U., López, L.A., Langa, C., Fabra, A., Letarte, M. & Bernabeu, C. (1996) Endoglin modulates cellular responses to TGF-β1. Journal of Cell Biology, 133, 1109-1121.
30. Lemke, H., Hammerling, G.J., Hofmann, C. & Rajewsky, K. (1978) Hybrid cell lines secreting monoclonal antibody specific for major histocompatibility antigens of the mouse. Nature, 271, 249-251.
31. Lundell, B.I., McCarthy, J.B., Kovach, N.L. & Verfaillie, C.M. (1996) Activation-dependent α5β1 integrin-mediated adhesion to fibronectin decreases proliferation of chronic myelogenous leukemia progenitors and K562 cells. Blood, 87, 2450-2458.
32. Massagué, J. (1987) Identification of receptors for type-β transforming growth factor. Methods in Enzymology, 146, 174-195.
33. Massagué, J. (1996) TGF-β signaling: receptors, transducers, and mad proteins. Cell, 85, 947-950.
34. Massagué, J., Attisano, L. & Wrana, J.L. (1994) The TGF-β family and its composite receptors. Trends in Cellular Biology, 4, 172-178.
35. Massagué, J. & Polyak, K. (1995) Mammalian antiproliferative signals and their targets. Current Opinion in Genetics and Development, 5, 91-96.
36. McAllister, K.A., Grogg, K.M., Johnson, D.W., Gallione, C.J., Baldwin, M.A., Jackson, C.E., Helmbold, E.A., Markel, D.S., McKinnon, W.C., Murrell, J., McCorminck, M.K., Pericak-Vance, M.A., Heutink, P., Oostra, B.A., Haitjema, T., Westerman, C.J.J., Porteus, M.E., Guttmacher, A.E., Letarte, M. & Marchuk, D.A. (1994) Endoglin, a TGF-β-binding protein of endothelial cells, is the gene for hereditary haemorrhagic telangiectasia type 1. Nature Genetics, 8, 345-351.
37. Moore, K.A., Pytowski, B., Witte, L., Hicklin, D. & Lemisschka, I.R. (1997) Hematopoietic activity of a stromal cell transmembrane protein containing epidermal growth factor-like repeat motifs. Proceedings of the National Academy of Sciences of the United States of America, 94, 4011-4016.
38. Ohta, M., Greenberger, J.S., Anklesaria, P., Bassols, A. & Massagué, J. (1987) Two forms of transforming growth factor-β distinguished by multipotential haematopoietic progenitor cells. Nature, 529, 559-541.
39. Ottmann, O.G. & Pelus, L.M. (1988) Differential proliferative effects of transforming growth factor-β on human hematopoietic progenitor cells. Journal of Immunology, 140, 2661-2665.
40. Robledo, M.M., Hidalgo, A., Lastres, P., Arroyo, A.G., Bernabeu, C., Sánchez-Madrid, F. & Teixidó, J. (1996) Characterization of TGF-β1-binding proteins in human bone marrow stromal cells. British Journal of Haematology, 93, 507-514.
41. Robledo, M.M., Sanz-Rodríguez, F., Hidalgo, A. & Teixidó, J. (1998) Differential use of VLA-4 and VLA-5 integrins by hematopoietic precursors and myeloma cells to adhere to TGF-1-treated bone marrow stroma. Journal of Biological Chemistry, In press.
42. Rokhlin, O.W., Cohen, M.B., Kubagawa, H., Letarte, M. & Cooper, M.D. (1995) Differential expression of endoglin on fetal and adult hematopoietic cells in human bone marrow. Journal of Immunology, 154, 4456-4465.
43. Roldán, E., García-Pardo, A. & Brieva, J.A. (1992) VLA-4-fibronectin interaction is required for the terminal differentiation of human bone marrow cells capable of spontaneous and high rate immunoglobin secretion. Journal of Experimental Medicine, 175, 1739-1747.
44. low cells in which anti-TGF-β up-modulates c-kit. Blood, 86, 1729-1735.
45. Simmons, P.J. & Torok-Storb, B. (1991) Identification of stromal cell precursors in human bone marrow by a novel monoclonal antibody, STRO-1. Blood, 78, 55-62.
46. Tang, N., Nuccie, B.L., Ritterman, I., Liesveld, J.L., Abboud, C.N. & Ryan, D.H. (1997) TGF-β down-regulates stromal IL-7 secretion and inhibits proliferation of human B cell precursors. Journal of Immunology, 159, 117-125.
47. hi stem cells to bone marrow stroma. Journal of Clinical Investigation, 90, 558-567.
48. Urashima, M., Ogata, A., Chuhan, D., Hatziyanni, M., Vidriales, M.B., Dedera, D.A., Schlossman, R.L. & Anderson, K.C. (1996) Transforming growth factor-β1: differential effects on multiple myeloma versus normal B cells. Blood, 87, 1928-1938.
49. Wahl, S.M., Hunt, D.E., Wakefield, L.M., McCartney-Francis, N., Wahl, L.M., Roberts, A.B. & Sporn, M.B. (1987) Transforming growth factor type β induces monocyte chemotaxis and growth factor production. Proceedings of the National Academy of Sciences of the United States of America, 84, 5788-5792.
50. Wrana, J.L., Attisano, L., Wieser, R., Ventura, F. & Massagué, J. (1994) Mechanism of activation of the TGF-β receptor. Nature, 370, 341-343.
51. Yamakage, A., Kikuchi, K., Smith, E.A., LeRoy, C.L. & Trojanowska, M. (1992) Selective upregulation of platelet-derived growth factor-β receptors by transforming growth factor β in scleroderma fibroblasts. Journal of Experimental Medicine, 175, 1227-1234.
52. Yamashita, H., Ichijo, H., Grimsby, S., Morén, A., ten Dijke, P. & Miyazono, K. (1994) Endoglin forms a heteromeric complex with the signaling receptors for transforming growth factor-β. Journal of Biological Chemistry, 269, 1995-2001.
53. Zhang, H., Shaw, A.R.E., Mak, A. & Letarte, M. (1996) Endoglin is a component of the transforming growth factor (TGF)-β receptor complex of human pre-B leukemic cells. Journal of Immunology, 156, 565-573.