Role of H2O2 in changing β-adrenoceptor and adenylyl cyclase in ischemia-reperfused hearts

Molecular and Cellular Biochemistry

Volumn 186, Issue 1-2, 1998, Pages 99-106

  Persad, Sujata ^a   Panagia, Vincenzo ^a   Dhalla, Naranjan S ^a,b  

^a UNIVERSITY OF MANITOBA   (Canada)

^b ST BONIFACE GENERAL HOSPITAL RESEARCH CENTRE   (Canada)

Author keywords

Cardiac adrenoceptors; Cardiac adenylyl cyclase; H2o2 and the heart; Inotropic effect of isoproterenol; Oxidative stress

Indexed keywords

ADENYLATE CYCLASE; BETA ADRENERGIC RECEPTOR; CATALASE; FORSKOLIN; GUANINE NUCLEOTIDE BINDING PROTEIN; HYDROGEN PEROXIDE; ISOPRENALINE; MANNITOL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; HEART MUSCLE; HEART MUSCLE ISCHEMIA; INOTROPISM; ISOLATED HEART; MALE; NONHUMAN; RAT; RECEPTOR AFFINITY; RECEPTOR DENSITY; REPERFUSION INJURY; SIGNAL TRANSDUCTION; ANIMAL; DRUG EFFECT; HEART; HEART CONTRACTION; IN VITRO STUDY; METABOLISM; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT;

ADENYLATE CYCLASE; ANIMALS; GTP-BINDING PROTEINS; HEART; HYDROGEN PEROXIDE; ISOPROTERENOL; MALE; MYOCARDIAL CONTRACTION; MYOCARDIAL REPERFUSION INJURY; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, ADRENERGIC, BETA; SIGNAL TRANSDUCTION;

EID: 0031595048     PISSN: 03008177     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1006823531286     Document Type: Article

References (32)

1. Cochrane CG: Cellular injury by oxidants. Am J Med 91: 235-305, 1991
2. Kaul N, Siveski-Iliskovic N, Hill M, Slezak J, Singal PK: Free radicals and the heart. J Pharmacol Toxicol Meth 30: 55-67, 1993
3. Kukreja RC, Hess ML: The oxygen free radical system: From equation through membrane-protein interactions to cardiovascular injury and protection. Cardiovasc Res 26: 641-655, 1992
4. Fliss H, Masika M, Eley DW, Korecky B: Oxygen radical mediated protein oxidation in heart. In: PK Singal (ed). Oxygen Radicals in the Pathophysiology of Heart Disease. Kluwer Academic Publishers, Boston, 1988, pp71-90
5. 2+ exchange. Coronary Artery Disease 2: 397-407, 1991
6. Hayashi H, Miyata H, Watanabe H, Kobayashi A, Yamazaki N: Effects of hydrogen peroxide on action potentials and intracellular concentrations of guinea pig heart. Cardiovasc Res 23: 767-773, 1989
7. 2 and HOCl. Am J Physiol 25: C598-C607, 1989
8. Kaminishi K, Yanagishita T, Kako KJ: Oxidant injury to isolated heart cells. Can J Cardiol 5: 168-174, 1989
9. 2+-pump activity by oxygen free radicals. Am J Physiol 256: H368- H374, 1989
10. Rowe GT, Manson NH, Caplan M, Hess ML: Hydrogen peroxide and hydroxyl radical mediation of activated leukocyte depression of cardiac sarcoplasmic reticulum. Circ Res 53: 584-591, 1983
11. Bristow MR, Kantrowitz NE, Ginsburg R, Fowler MR: Beta adrenergic function in heart muscle disease and heart failure. J Mol Cell Cardiol 17, Suppl 2: 41-52, 1985
12. Dhalla NS, Pierce GN, Panagia V, Singal PK, Beamish RE: Calcium movements in relation to heart function. Basic Res Cardiol 77: 117-139, 1982
13. Stiles GL: Adrenergic receptor responsiveness and congestive heart failure. Am J Cardiol 67: 13C-17C, 1991
14. Haenen GRMM, Van Dansik P, Vermeulen NPE, Timmerman H, Bast A: The effect of hydrogen peroxide on β-adrenoceptor function in the heart. Free Rad Res Commun 4: 243-249, 1988
15. Kaneko M, Chapman DC, Ganguly PK, Beamish RE, Dhalla NS: Modification of cardiac adrenergic receptors by oxygen free radicals. Am J Physiol 260: H821-H826, 1991
16. Masuda H, Kaneko M, Hong RB, Ikegaya T, Hayashi H, Kobayashi A, Yamazaki N: Effects of hydrogen peroxide on stimulatory guanine nucleotide-binding protein in rat heart. Jpn Circ J 57: 1007-1015, 1993
17. Tan LM, Xenoyannis S, Feldman RD: Oxidant stress enhances adenylyl cyclase activation. Circ Res 77: 710-717, 1995
18. 2+-paradox). J Mol Cell Cardiol 27: 513-522, 1995
19. Dixon IMC, Lee S-L, Dhalla NS: Nitrendipine binding in congestive heart failure due to myocardial infarction. Circ Res 66: 782-788, 1990
20. Munson PJ, Rodbard D: Ligand: A versatile computerized approach for characterization of ligand binding systems. Anal Biochem 107: 220-239, 1980
21. Persad S, Takeda S, Panagia V, Dhalla NS: β-adrenoceptor-linked signal transduction in ischemic-reperfused heart and scavenging of oxyradicals. J Mol Cell Cardiol 29: 545-558, 1997
22. Salomon Y, Londos C, Rodbell M: A highly sensitive adenylate cyclase assay. Anal Biochem 58: 541-548, 1974
23. Kaneko M, Lee S-L, Wolf CM, Dhalla NS: Reduction of calcium channel antagonist binding sites by oxygen free radicals in rat heart. J Mol Cell Cardiol 21: 235-243, 1989
24. Bristow MR, Ginsberg R, Strasberg A, Montgomery W, Minobe W: Pharmacology and inotropic potential of forskolin in the human heart. J Clin Invest 74: 212-223, 1984
25. Peters R: Lateral mobility of proteins and lipids in the radical membrane and the activation of adenylyl cyclase by adrenergic receptors. FEBS Lett 243: 1-7, 1988
26. Paradisi L, Parangini C, Parola M, Barreva G, Dianzani MU: Effects of 4-hydroxyneonatal on adenylate cyclase and 5′-nuelcotidase activities in rat liver plasma membranes. Chem Biol Interac 53: 209-217, 1985
27. Haenen GRMM, Plug HJM, Vermeulen NPE, Timmerman H, Bast A: Contribution of 4-hydroxy-2,3-trans-neonatal to the reduction of β-adrenoceptor function by oxidative stress. Life Sci 45: 71-76, 1989
28. Padersen SE, Ross EM: Functional activation of β-adrenergic receptors by thiol in the presence or absence of agonist. J Biol Chem 260: 14150-14157, 1985
29. Skurat AV, Yurkova MS, Varanova LA, Gulyaev NN, Bulargina TV, Severin ES: Evidence for the existence of a sulfhydryl group in the adenylate cyclase active site. Biochem Int 10: 451-461, 1985
30. Turrens BE, Beconi M, Barilla J, Chavez VB, McCord JM: Mitochondrial generation of oxygen radicals during reoxygenation of ischemic tissue. Free Rad Res Commun 12: 681-689, 1991
31. Homey CJ, Vatner SF, Vatner DE: β-adrenergic receptor regulation in the heart in pathophysiological states: abnormal adrenergic responsiveness in cardiac disease. Annu Rev Physiol 53: 137-159, 1991
32. Megg LG, Huang H, Li P, Capasso JM, Anversa P: Chronic nonocclusive coronary artery constriction in rats, β-adrenoceptor signal transduction and ventricular failure. J Clin Invest 88: 1940-1946, 1991