-
1
-
-
0024316466
-
DNA topoisomerase poisons as antitumor drugs
-
Liu LF. DNA topoisomerase poisons as antitumor drugs. Annu Rev Biochem 1989; 58: 351-75.
-
(1989)
Annu Rev Biochem
, vol.58
, pp. 351-375
-
-
Liu, L.F.1
-
2
-
-
0015222656
-
Interaction between DNA and Escherichia coli protein mu
-
Wang JC. Interaction between DNA and Escherichia coli protein mu. J Mol Biol 1971; 55: 523-33.
-
(1971)
J Mol Biol
, vol.55
, pp. 523-533
-
-
Wang, J.C.1
-
4
-
-
0014895176
-
Preliminary pharmacolgic and clinical evaluation of camptothecin sodium (NSC-100880)
-
Gottleib JA, Guaarino AM, Call JB. Preliminary pharmacolgic and clinical evaluation of camptothecin sodium (NSC-100880). Cancer Chemother Rep 1970; 54: 461-70.
-
(1970)
Cancer Chemother Rep
, vol.54
, pp. 461-470
-
-
Gottleib, J.A.1
Guaarino, A.M.2
Call, J.B.3
-
5
-
-
0029084773
-
CPT-11 (irinotecan) in the treatment of colorectal cancer
-
Armand JP, Ducreux M, Mahjoubi M, et al. CPT-11 (irinotecan) in the treatment of colorectal cancer. Eur J Cancer 1995; 31A: 1283-7.
-
(1995)
Eur J Cancer
, vol.31 A
, pp. 1283-1287
-
-
Armand, J.P.1
Ducreux, M.2
Mahjoubi, M.3
-
6
-
-
0027957126
-
The treatment of non-small cell lung cancer current perspectives, controversies, and future directions
-
Bunn PA, Jr. The treatment of non-small cell lung cancer current perspectives, controversies, and future directions. Semin Oncol 1994; 21: 49-59.
-
(1994)
Semin Oncol
, vol.21
, pp. 49-59
-
-
Bunn Jr., P.A.1
-
7
-
-
0030248494
-
The clinical status of irinotecan (CPT-11), a novel water soluble camptothecin analogue
-
O'Reilly S, Rowinsky EK. The clinical status of irinotecan (CPT-11), a novel water soluble camptothecin analogue. Crit Rev Oncol-Hematol 1996; 24: 47-70.
-
(1996)
Crit Rev Oncol-Hematol
, vol.24
, pp. 47-70
-
-
O'Reilly, S.1
Rowinsky, E.K.2
-
8
-
-
15144360173
-
Phase II study of topotecan in patients with non-small cell lung cancer (NSCLC) previously untreated
-
Perez-Soler R, Glisson BS, Kane J, Lee J, Raber MN, Hong WK. Phase II study of topotecan in patients with non-small cell lung cancer (NSCLC) previously untreated. Proc Am Soc Clin Oncol 1994; 13: A1223.
-
(1994)
Proc Am Soc Clin Oncol
, vol.13
-
-
Perez-Soler, R.1
Glisson, B.S.2
Kane, J.3
Lee, J.4
Raber, M.N.5
Hong, W.K.6
-
9
-
-
15144351270
-
Phase D Study of topotecan in patients with small cell lung cancer (SCLC) refractory to etoposide
-
Perez-Soler R, Glisson BS, Lee JS, et al. Phase D Study of topotecan in patients with small cell lung cancer (SCLC) refractory to etoposide. Proc Am Soc Clin Oncol 1995; 14: A1078.
-
(1995)
Proc Am Soc Clin Oncol
, vol.14
-
-
Perez-Soler, R.1
Glisson, B.S.2
Lee, J.S.3
-
10
-
-
0030826929
-
Topoisomerase I inhibitors: Review and update
-
Rothenberg ML. Topoisomerase I inhibitors: review and update. Ann Oncol 1997; 8: 837-55.
-
(1997)
Ann Oncol
, vol.8
, pp. 837-855
-
-
Rothenberg, M.L.1
-
11
-
-
0030703255
-
A phase II study of topotecan administered five times daily in patients with advanced gastric cancer
-
Saltz LB, Schwartz GK, Ilson DH, Quan V, Kelsen DP. A phase II study of topotecan administered five times daily in patients with advanced gastric cancer. Am J Clin Oncol 1997; 20: 621-5.
-
(1997)
Am J Clin Oncol
, vol.20
, pp. 621-625
-
-
Saltz, L.B.1
Schwartz, G.K.2
Ilson, D.H.3
Quan, V.4
Kelsen, D.P.5
-
12
-
-
0029448132
-
Recent clinical advances with camptothecin analogues
-
Slichenmyer WJ, Donehower RC. Recent clinical advances with camptothecin analogues. Cancer Treat Res 1995; 78: 29-43.
-
(1995)
Cancer Treat Res
, vol.78
, pp. 29-43
-
-
Slichenmyer, W.J.1
Donehower, R.C.2
-
13
-
-
8944222113
-
Phase II evaluation of topotecan for pediatric central nervous system tumors
-
Blaney SM, Phillips PC, Packer RJ, et al. Phase II evaluation of topotecan for pediatric central nervous system tumors. Cancer 1996; 78: 527-31.
-
(1996)
Cancer
, vol.78
, pp. 527-531
-
-
Blaney, S.M.1
Phillips, P.C.2
Packer, R.J.3
-
14
-
-
10244270659
-
Phase I trial and pharmacokinetic (PK) and pharmacodynamics (PD) study of topotecan using a five-day course in children with refractory solid tumors: A pediatric oncology group study
-
Tubergen DG, Stewart CF, Pratt CB, et al. Phase I trial and pharmacokinetic (PK) and pharmacodynamics (PD) study of topotecan using a five-day course in children with refractory solid tumors: a pediatric oncology group study. J Pediatr Hematol/Oncol 1996; 18: 352-61.
-
(1996)
J Pediatr Hematol/Oncol
, vol.18
, pp. 352-361
-
-
Tubergen, D.G.1
Stewart, C.F.2
Pratt, C.B.3
-
15
-
-
0027511840
-
Plasma and cerebrospinal fluid pharmacokinetic study of topotecan in non-human primates
-
Blaney SM, Cole DE, Balis FM, Godwin K, Poplack DG. Plasma and cerebrospinal fluid pharmacokinetic study of topotecan in non-human primates. Cancer Res 1993; 53: 725-7.
-
(1993)
Cancer Res
, vol.53
, pp. 725-727
-
-
Blaney, S.M.1
Cole, D.E.2
Balis, F.M.3
Godwin, K.4
Poplack, D.G.5
-
16
-
-
0025812689
-
Camptothecin cytotxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA
-
Ryan AJ, Squires S, Strutt HL, Johnson RT. Camptothecin cytotxicity in mammalian cells is associated with the induction of persistent double strand breaks in replicating DNA. Nucleic Acids Res 1991; 19: 3295-300.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 3295-3300
-
-
Ryan, A.J.1
Squires, S.2
Strutt, H.L.3
Johnson, R.T.4
-
17
-
-
0028267240
-
Camptothecins: From bench research to hosptal wards
-
Potmesil M. Camptothecins: from bench research to hosptal wards. Cancer Res 1994; 54: 1431-9.
-
(1994)
Cancer Res
, vol.54
, pp. 1431-1439
-
-
Potmesil, M.1
-
18
-
-
0030455392
-
Treatment of central nervous system xenografts with camptothecins
-
Friedman HS, Houghton PJ. Treatment of central nervous system xenografts with camptothecins. Ann NY Acad Sci 1996; 803: 210-2.
-
(1996)
Ann NY Acad Sci
, vol.803
, pp. 210-212
-
-
Friedman, H.S.1
Houghton, P.J.2
-
19
-
-
15144344517
-
Schedule-dependent activity of topoisomerase I inhibitors in intracranial medulloblastoma and glioma xenografts
-
in press
-
Phillips PC, Kaufmann S, Catterall M, Covin OM. Schedule-dependent activity of topoisomerase I inhibitors in intracranial medulloblastoma and glioma xenografts. Clin Cancer Res 1998; in press.
-
(1998)
Clin Cancer Res
-
-
Phillips, P.C.1
Kaufmann, S.2
Catterall, M.3
Covin, O.M.4
-
20
-
-
0027529978
-
Interaction of topoisomerase I inhibitors with radiation in cis-diammmedichloroplatinum(II)-sensitive and -resistant cells in vitro and in the FSAIIC fibrosarcoma in vivo
-
Boscia RE, Korbut T, Holden SA, Ara G, Teicher BA. Interaction of topoisomerase I inhibitors with radiation in cis-diammmedichloroplatinum(II)-sensitive and -resistant cells in vitro and in the FSAIIC fibrosarcoma in vivo. Int J Cancer 1993; 53: 118-23.
-
(1993)
Int J Cancer
, vol.53
, pp. 118-123
-
-
Boscia, R.E.1
Korbut, T.2
Holden, S.A.3
Ara, G.4
Teicher, B.A.5
-
21
-
-
0026578227
-
Potentiation of radiation response in human carcinoma cells in vitro and murine fibrosarcoma in invo by topotecan, an inhibitor of DNA topoisomerase I
-
Kim JH, Kim SH, Kolozxvary A, Khil MS. Potentiation of radiation response in human carcinoma cells in vitro and murine fibrosarcoma in invo by topotecan, an inhibitor of DNA topoisomerase I. Int J Radiat Oncol Biol Phys 1992; 22: 515-8.
-
(1992)
Int J Radiat Oncol Biol Phys
, vol.22
, pp. 515-518
-
-
Kim, J.H.1
Kim, S.H.2
Kolozxvary, A.3
Khil, M.S.4
-
22
-
-
0026328062
-
Synergic cell killing by ionizing radiation and topoisomerase I inhibitor topotecan (SK&F 104864)
-
Mattern MR, Hofman GA, McCabe FL, Johnson RK. Synergic cell killing by ionizing radiation and topoisomerase I inhibitor topotecan (SK&F 104864). Cancer Res 1991; 51: 5813-6.
-
(1991)
Cancer Res
, vol.51
, pp. 5813-5816
-
-
Mattern, M.R.1
Hofman, G.A.2
McCabe, F.L.3
Johnson, R.K.4
-
23
-
-
0028328850
-
Interaction of ionizing radiation with the topoisomerase I poison camptothecin in growing V-79 and HeLa cells
-
Hennequin C, Giocanti N, Balosso J, Favaudon V. Interaction of ionizing radiation with the topoisomerase I poison camptothecin in growing V-79 and HeLa cells. Cancer Res 1994; 54: 1720-8.
-
(1994)
Cancer Res
, vol.54
, pp. 1720-1728
-
-
Hennequin, C.1
Giocanti, N.2
Balosso, J.3
Favaudon, V.4
-
24
-
-
0026441127
-
Posttreatment exposure to camptothecin enhances the lethal effects of X-rays on radioresistant human alignant melanoma cells
-
Boothman DA, Wang M, Schea RA, Burrows HL, Strickfaden S, Owens JK. Posttreatment exposure to camptothecin enhances the lethal effects of X-rays on radioresistant human alignant melanoma cells. Int J Radiat Oncol Biol Phys 1992; 24: 939-48.
-
(1992)
Int J Radiat Oncol Biol Phys
, vol.24
, pp. 939-948
-
-
Boothman, D.A.1
Wang, M.2
Schea, R.A.3
Burrows, H.L.4
Strickfaden, S.5
Owens, J.K.6
-
25
-
-
0028153260
-
Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: A rational approach to clinical protocol design
-
Chou T-C, Motzer RJ, Tong Y, Bosl GJ. Computerized quantitation of synergism and antagonism of taxol, topotecan, and cisplatin against human teratocarcinoma cell growth: a rational approach to clinical protocol design. J Natl Cancer Inst 1994; 86: 1517-24.
-
(1994)
J Natl Cancer Inst
, vol.86
, pp. 1517-1524
-
-
Chou, T.-C.1
Motzer, R.J.2
Tong, Y.3
Bosl, G.J.4
-
26
-
-
0030068657
-
Synergism between cisplatin and topoisomerase I inhibitors, NB-506 and SN-38, in human small cell lung cancer cells
-
Fukuda M, Nishio K, Kanzawa F, et al. Synergism between cisplatin and topoisomerase I inhibitors, NB-506 and SN-38, in human small cell lung cancer cells. Cancer Res 1996; 56: 789-93
-
(1996)
Cancer Res
, vol.56
, pp. 789-793
-
-
Fukuda, M.1
Nishio, K.2
Kanzawa, F.3
-
27
-
-
0028099895
-
Schedule dependent cytotoxicity of topotecan alone and in combination chemotherapy regimens
-
Cheng M-F, Chatterjee S, Berger NA. Schedule dependent cytotoxicity of topotecan alone and in combination chemotherapy regimens. Oncol Res 1994; 6: 269-79.
-
(1994)
Oncol Res
, vol.6
, pp. 269-279
-
-
Cheng, M.-F.1
Chatterjee, S.2
Berger, N.A.3
-
28
-
-
0030887027
-
Effect of CPT-11 in combination with other anticancer agents in lung cancer cells
-
Pei XH, Nakanishi Y, Takayama K, et al. Effect of CPT-11 in combination with other anticancer agents in lung cancer cells. Anti-Cancer Drugs 1997; 8: 231-7.
-
(1997)
Anti-Cancer Drugs
, vol.8
, pp. 231-237
-
-
Pei, X.H.1
Nakanishi, Y.2
Takayama, K.3
-
29
-
-
0025734164
-
Medulloblastoma: Tumor biological and clinical perspectives
-
Friedman HS, Oakes WJ, Bigner SH, Wikstrand CJ, Bigner DD. Medulloblastoma: tumor biological and clinical perspectives. J Neuro-Oncol 1991; 11: 1-15.
-
(1991)
J Neuro-Oncol
, vol.11
, pp. 1-15
-
-
Friedman, H.S.1
Oakes, W.J.2
Bigner, S.H.3
Wikstrand, C.J.4
Bigner, D.D.5
-
30
-
-
0026594602
-
Sequential administration of captothecin and etoposide circumvents the antagonistic cytotoxicity of simultaneous drug administration in slowly growing human conlon carcinoma HT-29 cells
-
Bertrand R, O'Connor PM, Kerrigan D, Pommier Y Sequential administration of captothecin and etoposide circumvents the antagonistic cytotoxicity of simultaneous drug administration in slowly growing human conlon carcinoma HT-29 cells. Eur J Cancer 1992; 28A: 743-8.
-
(1992)
Eur J Cancer
, vol.28 A
, pp. 743-748
-
-
Bertrand, R.1
O'Connor, P.M.2
Kerrigan, D.3
Pommier, Y.4
-
31
-
-
0024329234
-
Effect of lonidamine on the cytotoxicity of four alkylating agents in vitro
-
EF
-
Rosbe KW, Brann TW, Holden SA, Teicher BA, III EF. Effect of lonidamine on the cytotoxicity of four alkylating agents in vitro. Cancer Chemother Pharmacol 1989; 25: 32-6.
-
(1989)
Cancer Chemother Pharmacol
, vol.25
, pp. 32-36
-
-
Rosbe, K.W.1
Brann, T.W.2
Holden, S.A.3
Teicher III, B.A.4
-
32
-
-
0026589474
-
Statistical analysis of drug combinations for synergism
-
Tallarida RJ. Statistical analysis of drug combinations for synergism. Pain 1992; 49: 93-7.
-
(1992)
Pain
, vol.49
, pp. 93-97
-
-
Tallarida, R.J.1
-
33
-
-
0024847290
-
What is Synergy?
-
Berenbaum MC. What is Synergy? Pharmacol Rev 1989; 41: 93-141.
-
(1989)
Pharmacol Rev
, vol.41
, pp. 93-141
-
-
Berenbaum, M.C.1
-
34
-
-
0000994406
-
Analysis of combined durg effects: A new look at a very old problem
-
Chou T-C, Talalay P. Analysis of combined durg effects: a new look at a very old problem. Trends Pharm Sci 1983; 450-4.
-
(1983)
Trends Pharm Sci
, pp. 450-454
-
-
Chou, T.-C.1
Talalay, P.2
-
35
-
-
0021930508
-
Establisment of human medulloblastoma cell line and its heterotransplantation into nude mice
-
Jacobsen PF, Jenkyn PF, Papadimitriou JM. Establisment of human medulloblastoma cell line and its heterotransplantation into nude mice. J Neuropathol Exp Neural 1985; 44: 472-85.
-
(1985)
J Neuropathol Exp Neural
, vol.44
, pp. 472-485
-
-
Jacobsen, P.F.1
Jenkyn, P.F.2
Papadimitriou, J.M.3
-
36
-
-
0017360661
-
Synergy, additivism and antagonism in immunosuppression: A critical review
-
Berenbaum MC. Synergy, additivism and antagonism in immunosuppression: a critical review. Clin Exp Immunol 1977; 28: 1-18.
-
(1977)
Clin Exp Immunol
, vol.28
, pp. 1-18
-
-
Berenbaum, M.C.1
-
37
-
-
0345801106
-
Assessment of the degree of drug interaction where the response variable is discrete
-
Geco WR, Lawrence DD. Assessment of the degree of drug interaction where the response variable is discrete Am Stat Ass Proc Biopharmaceut Sect 1989: 226-31.
-
(1989)
Am Stat Ass Proc Biopharmaceut Sect
, pp. 226-231
-
-
Geco, W.R.1
Lawrence, D.D.2
-
38
-
-
0008789631
-
Importance of the structural component of generalized non-linear models for joint drug action
-
Geco WR. Importance of the structural component of generalized non-linear models for joint drug action. Am Stat Ass Proc Biopharmaceut Sect 1989; 183-8.
-
(1989)
Am Stat Ass Proc Biopharmaceut Sect
, pp. 183-188
-
-
Geco, W.R.1
-
39
-
-
0018290949
-
Isobologram analysis of X-ray-BCNU interactions in vitro
-
Deen DF, Williams ME. Isobologram analysis of X-ray-BCNU interactions in vitro. Radiat Res 1979; 79: 483-91.
-
(1979)
Radiat Res
, vol.79
, pp. 483-491
-
-
Deen, D.F.1
Williams, M.E.2
-
40
-
-
0025893984
-
Antagonism between camptothecin and Topoisomerase II-directed chemotherapeutic agents in a human leukeria cell line
-
Kaufmann SH. Antagonism between camptothecin and Topoisomerase II-directed chemotherapeutic agents in a human leukeria cell line. Cancer Res 1991; 51: 1-9.
-
(1991)
Cancer Res
, vol.51
, pp. 1-9
-
-
Kaufmann, S.H.1
-
41
-
-
0025133118
-
Involvement of nucleic acid synthesis in cell killing mechnasims of topoisomerase poisons
-
D'Arpa P, Beardmore C, Liu LF. Involvement of nucleic acid synthesis in cell killing mechnasims of topoisomerase poisons. Cancer Res 1990; 50: 6919-24.
-
(1990)
Cancer Res
, vol.50
, pp. 6919-6924
-
-
D'Arpa, P.1
Beardmore, C.2
Liu, L.F.3
-
42
-
-
0030773461
-
Down-regulation of topoisomerase II by camptothecin does not prevent additive activity of the topoisomerase II inhibitor etoposide in vitro
-
Stahl M, Kasimir-Bauer S, Harstrick A. Down-regulation of topoisomerase II by camptothecin does not prevent additive activity of the topoisomerase II inhibitor etoposide in vitro. Anti-Cancer Drugs 1997; 8: 671-6.
-
(1997)
Anti-Cancer Drugs
, vol.8
, pp. 671-676
-
-
Stahl, M.1
Kasimir-Bauer, S.2
Harstrick, A.3
-
43
-
-
0018425119
-
Exploitable mechanisms in combined radiotherapy-chemotherapy: The concept of additivity
-
Steel GG, Peckham MJ. Exploitable mechanisms in combined radiotherapy-chemotherapy: the concept of additivity. Int J Radiat Oncol Biol Phys 1979; 5: 85-91.
-
(1979)
Int J Radiat Oncol Biol Phys
, vol.5
, pp. 85-91
-
-
Steel, G.G.1
Peckham, M.J.2
-
44
-
-
15144353387
-
A new statistical method for testing a combination therapy's superiority to both of its components
-
Ng T-H, Hung HMJ, Chi GYH. A new statistical method for testing a combination therapy's superiority to both of its components. Am Stat Ass Proc Biopharmaceut Sect 1989: 60-5.
-
(1989)
Am Stat Ass Proc Biopharmaceut Sect
, pp. 60-65
-
-
Ng, T.-H.1
Hung, H.M.J.2
Chi, G.Y.H.3
-
46
-
-
0024208909
-
A statistical approach to the construction and analysis of isobolograms
-
Carter WH, Gennings C, Staniswalis JG, Campbell ED, While KL. A statistical approach to the construction and analysis of isobolograms. J Am Coll Toxicol 1988; 7: 963-73.
-
(1988)
J Am Coll Toxicol
, vol.7
, pp. 963-973
-
-
Carter, W.H.1
Gennings, C.2
Staniswalis, J.G.3
Campbell, E.D.4
While, K.L.5
-
47
-
-
0024582179
-
Lack of in vitro synergy between etoposide and cis-diammine-dichloro-platinum(II)
-
Tsai C-M, Gazdar AF, Venzon DJ, et al. Lack of in vitro synergy between etoposide and cis-diammine-dichloro-platinum(II). Cancer Res 1989; 49: 2390-7.
-
(1989)
Cancer Res
, vol.49
, pp. 2390-2397
-
-
Tsai, C.-M.1
Gazdar, A.F.2
Venzon, D.J.3
-
48
-
-
0026619838
-
Comments on the evaluation of drug interaction using isobolographic an analysis of variance
-
Miaskowski C, Levine JD. Comments on the evaluation of drug interaction using isobolographic an analysis of variance. Pain 1992; 51: 383-7.
-
(1992)
Pain
, vol.51
, pp. 383-387
-
-
Miaskowski, C.1
Levine, J.D.2
|