39K NMR measurement of intracellular potassium during ischemia in the perfused guinea pig heart

Magnetic Resonance in Medicine

Volumn 40, Issue 4, 1998, Pages 544-550

  Radford, Nina B ^a,d   Babcock, Evelyn E ^a   Richman, Angela ^a   Szczepaniak, Lidia ^a   Malloy, Craig R ^a,c   Sherry, A Dean ^a,b  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF DALLAS   (United States)

^c VA NORTH TEXAS HEALTH CARE SYSTEM   (United States)

^d Rogers Magnetic Resonance Center   (United States)

Author keywords

Cations; Ischemia; NMR; Potassium

Indexed keywords

ABSORPTION SPECTROSCOPY; ATOMIC ABSORPTION SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; POSITIVE IONS; POTASSIUM;

ATOMIC ABSORPTION SPECTROSCOPY; BASELINE LEVELS; EXPERIMENTAL CONDITIONS; EXTRACELLULAR; EXTRACELLULAR SPACE; HYPERFINE SHIFT; ISCHEMIA; REPERFUSION;

MAMMALS;

POTASSIUM; DIAGNOSTIC AGENT; ORGANOMETALLIC COMPOUND; ORGANOPHOSPHORUS COMPOUND; THULIUM; THULIUM(III) 1,4,7,10 TETRAAZACYCLODODECANE N,N',N'',N''' TETRAMETHYLENEPHOSPHONATE; THULIUM(III) 1,4,7,10-TETRAAZACYCLODODECANE-N,N',N'',N'''-TETRAMETHYLENEPHOSPHONATE;

ANIMAL TISSUE; ARTICLE; ATOMIC ABSORPTION SPECTROMETRY; HEART MUSCLE ISCHEMIA; HEART MUSCLE REPERFUSION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; POTASSIUM CELL LEVEL; POTASSIUM TRANSPORT; ANIMAL; GUINEA PIG; HEART MUSCLE; METABOLISM; METHODOLOGY; PERFUSION;

ANIMALS; GUINEA PIGS; MAGNETIC RESONANCE SPECTROSCOPY; MYOCARDIAL ISCHEMIA; MYOCARDIUM; ORGANOMETALLIC COMPOUNDS; ORGANOPHOSPHORUS COMPOUNDS; PERFUSION; POTASSIUM; SPECTROPHOTOMETRY, ATOMIC; THULIUM;

EID: 0031594955     PISSN: 07403194     EISSN: None     Source Type: Journal    
DOI: 10.1002/mrm.1910400407     Document Type: Article

References (40)

1. G. J. Grover, J. R. McCullough, D. E. Henry, M. L. Conder, P. G. Sleph, Anti-ischemic effects of the potassium channel activators pinacidil and cromakalim and the reversal of these effects with the potassium channel blocker glyburide. J. Pharmacol. Exp. Ther. 2519, 98-1043 (1989).
2. J. A. Auchampach, M. Maruyama, I. Cavero, G. J. Gross, Pharmacological evidence for a role of ATP-dependent potassium channels in myocardial stunning. Circulation 86, 311-319 (1992).
3. G. J. Grover, P. G. Sleph, S. Dzwonczyk, Pharmacologic profile of cromakalim in the treatment of myocardial ischemia in isolated rat hearts and anesthetized dogs. J. Cardiovasc. Pharmacol. 16, 853-864 (1990).
4. + loss and arrhythmias in rat hearts: effect of glibenclamide. a sulfonylurea. Circ. Res. 66, 478-485 (1990).
5. + activity in swine. Circulation 61, 768-778 (1980).
6. + accumulation during myocardial ischemia in isolated rabbit heart. Am. J. Physiol. 242, H619-H628 (1982).
7. + channel. Circ. Res. 67, 835-843 (1990).
8. +, pH and activation in the pig. Circulation 72, 922-932 (1985).
9. J. B. Heijnis, R. Coronel, P. A. Van Zwieten, The effects of calcium antagonists on extracellular potassium accumulation during global ischemia in isolated perfused rat hearts. Cardiovasc. Drug Ther. 5, 1035-1041 (1991).
10. W. E. Cascio, G. X. Van, A. G. Kleber, Passive electrical properties, mechanical activity, and extracellular potassium in arterially perfused and ischemic rabbit ventricular muscle. Circ. Res. 66, 1461-1473 (1990).
11. e changes during ischemia in rat heart. Am. J. Physiol. 263, H333-H340 (1992).
12. A. G. Kleber, Resting membrane potential, extracellular potassium activity, and intracellular sodium activity during acute global ischemia in isolated perfused guinea pig hearts. Circ. Res. 52, 442-450 (1983).
13. + loss during hypoxia, ischemia, and metabolic inhibition in mammalian ventricle. Circ. Res. 69, 623-637 (1991).
14. T. Crake, M. S. Kirby, P. A. Poole-Wilson. Potassium efflux from the myocardium during hypoxia: role of lactate ions. Cardiovasc. Res. 21, 886-891 (1987).
15. E. E. Ran, K. I. Shine, G. A. Langer, Potassium exchange and mechanical performance in anoxic mammalian myocardium. Am. J. Physiol. 232, H85-H94 (1977).
16. F. T. Thandroyen, D. Belloto, A. Katayama, H. K. Hagler, J. T. Willerson, L. M. Buja, Subcellular electrolyte alterations during progressive hypoxia and following reoxygenation in isolated neonatal rat ventricular myocytes. Circ. Res. 71, 106-119 (1992).
17. 39K nuclear magnetic resonance studies of perfused rat hearts: discrimination of intra- and extracellular ions using a shift reagent. Biophys. J. 48, 159-173 (1985).
18. D. Burstein, H. I. Litt, E. T. Fossel, NMR Characteristics of "visible" intracellular myocardial potassium in perfused rat hearts. Magn. Reson. Med. 9, 66-78 (1989).
19. 39K NMR detectability in rat tissue. Magn. Reson. Med. 17, 213-224 (1991).
20. S. Kuki, E. Suzuki, H. Watari, H. Takami, H. Matsuda, Y. Kawashima, Potassium-39 nuclear magnetic resonance observation of intracellular potassium without chemical shift reagents during metabolic inhibition in the isolated perfused rat heart. Circ. Res. 67, 401-405 (1990).
21. S. C.-K. Chu, Y. Xu, J. A. Balschi, C. S. Springer Jr, Bulk magnetic susceptibility shifts in NMR studies of compartmentalized samples: use of paramagnetic reagents. Magn. Reson. Med. 13, 239-262 (1993).
22. 39K detectability and relaxation constants in rat tissue. Magn. Reson. Med. 29, 68-76 (1993).
23. 23Na chemical shift imaging, in "Proc., SMRM, 9th Annual Meeting, New York, 1990," p. 39.
24. J. T. Flaherty, M. L. Weisfeldt, B. H. Bulkley, T. J. Gardner, V. L. Gott, W. E. Jacobus, Mechanisms of ischemic myocardial cell damage assessed by phosphorus-31 nuclear magnetic resonance. Circulation 65, 561-571 (1982).
25. 23Na magnetic resonance spectroscopy. Magn. Reson. Med. 39, 155-159 (1998).
26. 5 versus CoEDTA- as markers of extracellular tissue space. J. Appl. Physiol., in press.
27. E. Scheufler, T. Peters, Determination of extracellular space with nonradioactive CoEDTA and simultaneous estimation of Na, K, Ca and Mg contents in isolated guinea-pig heart preparations by atomic absorption spectrometry. Basic Res. Cardiol. 82, 341-347 (1987).
28. + shift agent for perfused rat hearts. Magn. Reson. Med. 15, 25-32 (1990).
29. E. T. Fossel, H. Hoefeler, Observation of intracellular potassium and sodium in the heart by NMR: a major fraction of potassium is "invisible." Magn. Reson. Med. 3, 534-540 (1986).
30. D. Burstein, E. T. Fossel, Nuclear magnetic resonance studies of intracellular ions in perfused frog heart. Am. J. Physiol. 252, H1138-H1146 (1987).
31. C. S. Springer, Biological systems: spin-3/2 nuclei, in "Encyclopedia of Nuclear Magnetic Resonance" (D. M. Grant, R. K. Harris, Eds.), p. 940, John Wiley & Sons, New York, 1996.
32. H. J. Berendsen, H. T. Edzes, The observation and general interpretation of sodium magnetic resonance in biological material. Ann. N. Y. Acad. Sci. 204, 459-485 (1973).
33. W. D. Rooney, C. S. Springer, A comprehensive approach to the analysis and interpretation of the resonances of spins 3/2 from living systems. NMR Biomed. 4, 209-236 (1991).
34. 39K nuclear magnetic resonance. Biophys. J. 51, 265-271 (1987).
35. +. Am. J. Physiol. 254, F401-F406 (1988).
36. C. O. Lee, H. A. Fozzard, Activities of potassium and sodium ions in rabbit heart muscle. J. Gen. Physiol. 65, 695-708 (1975).
37. J. S. Ingwall, K. Clarke, L. C. Stewart, M. Bernard, Cation movement across cell walls in intact tissues using MRS, in "Encyclopedia of Nuclear Magnetic Resonance" (D.M. Grant, R. K. Harris, Eds.), p. 1189, John Wiley & Sons, New York, 1996.
38. 87Rb NMR studies of the perfused rat heart. FEBS Lett. 242, 215-217 (1989).
39. 23Na NMR study. Circ. Res. 76, 839-851 (1995).
40. 31P-NMR study. Am. J. Physiol. 270, H1303-H1311 (1996).