Characterization of [125I]-PD164333, an ET(A) selective non-peptide radiolabelled antagonist, in normal and diseased human tissues

British Journal of Pharmacology

Volumn 123, Issue 2, 1998, Pages 223-230

  Davenport, Anthony P ^a   Kuc, Rhoda E ^a   Ashby, Michael J ^a   Patt, William C ^b   Doherty, Annette M ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b PFIZER INC   (United States)

Author keywords

Atherosclerosis; Endothelin ET(A) radioligand; Quantitative receptor autoradiography; Saphenous vein grafts

Indexed keywords

2 [[2 [[2 [[(HEXAHYDRO 1H AZEPIN 1 YL)CARBONYL]AMINO] 4 METHYLPENTANOYL]AMINO] 3 (1 METHYL 1H INDOL 3 YL)PROPIONYL]AMINO] 3 (2 PYRIDYL)PROPIONIC ACID; CYCLO(DEXTRO TRYPTOPHYL DEXTRO ASPARTYLPROLYL DEXTRO VALYLLEUCYL); ENDOTHELIN A RECEPTOR; ENDOTHELIN A RECEPTOR ANTAGONIST; ENDOTHELIN B RECEPTOR; ENDOTHELIN B RECEPTOR AGONIST; IODINE 125; N ACETYLENDOTHELIN 1 [6-21][11,15 ALANINE]; PD 164333; RADIOPHARMACEUTICAL AGENT; SARAFOTOXIN S6C; UNCLASSIFIED DRUG; 1,3 DIOXOLANE DERIVATIVE; CROTONIC ACID DERIVATIVE; DIAGNOSTIC AGENT; ENDOTHELIN 1; ENDOTHELIN RECEPTOR; LIGAND; RADIOACTIVE IODINE;

ADULT; AGED; AORTA; ARTICLE; AUTORADIOGRAPHY; BINDING AFFINITY; BRAIN CORTEX; CLINICAL ARTICLE; CONTROLLED STUDY; CORONARY ARTERY; DRUG BINDING; FEMALE; GRAY MATTER; HEART LEFT VENTRICLE; HUMAN; HUMAN TISSUE; KIDNEY; MALE; PIA ARTERY; PRIORITY JOURNAL; SAPHENOUS VEIN; WHITE MATTER; BRAIN; DRUG ANTAGONISM; DRUG STABILITY; HEART VENTRICLE; KINETICS; METABOLISM; MIDDLE AGED; SCINTISCANNING; ULTRASTRUCTURE;

ADULT; AORTA; AUTORADIOGRAPHY; BRAIN; CROTONIC ACIDS; DIOXOLES; DRUG STABILITY; ENDOTHELIN-1; FEMALE; HEART VENTRICLES; HUMANS; IODINE RADIOISOTOPES; KIDNEY; KINETICS; LIGANDS; MALE; MIDDLE AGED; RADIOPHARMACEUTICALS; RECEPTOR, ENDOTHELIN A; RECEPTORS, ENDOTHELIN;

EID: 0031594383     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0701597     Document Type: Article

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