The role of A3 adenosine receptors in central regulation of arterial blood pressure

British Journal of Pharmacology

Volumn 125, Issue 3, 1998, Pages 437-440

  Stella, Luigi ^a   De Novellis, Vito ^a   Marabese, Ida ^a   Berrino, Liberato ^a   Maione, Sabatino ^a   Filippelli, Amelia ^a   Rossi, Francesco ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

A3 receptors; Anaesthetized rats; Arterial blood pressure; Heart rate; N6 2 (4 aminophenyl) ethyladenosine (APNEA); Third ventricle

Indexed keywords

8 CYCLOPENTYL 1,3 DIPROPYLXANTHINE; ADENOSINE A1 RECEPTOR ANTAGONIST; ADENOSINE A3 RECEPTOR; ADENOSINE RECEPTOR STIMULATING AGENT; AMINOPHYLLINE; PERTUSSIS TOXIN; ADENOSINE RECEPTOR;

ANIMAL EXPERIMENT; ARTERIAL PRESSURE; ARTICLE; BLOOD PRESSURE REGULATION; CONTROLLED STUDY; HEART RATE; INTRACEREBROVENTRICULAR DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; ANIMAL; BLOOD PRESSURE; CENTRAL NERVOUS SYSTEM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; BLOOD PRESSURE; CENTRAL NERVOUS SYSTEM; HEART RATE; INJECTIONS, INTRAVENTRICULAR; MALE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P1;

EID: 0031593910     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702126     Document Type: Article

References (23)

1. BARRACO, R.A., JANUSZ, C.A., SCHOENER, E.P. & SIMPSON, L.L. (1990). Cardiorespiratory function is altered by picomole injections of 5′N-ethylcarboxamidoadenosine into the nucleus tractus solitarius of rats. Brain Res., 507, 234-246.
2. BARRACO, R.A. & PHILLIS, J.W. (1991). Subtypes of adenosine receptors in the brainstem mediate opposite blood pressure responses. Neuropharmacology., 30, 403-407.
3. BARRACO, R.A., PHILLIS, J.W., STAIR, R.E., CAMPBELL, W.R., MARCANTONIO, D.R. & SALAH, R.S. (1986). The effects of central injection of adenosine analogues on blood pressure and heart rate in rat. Neuropharmacology, 25, 675-680.
4. BARRACO, R.A., PHILLIS, J.W., STAIR, R.E., CAMPBELL, W.R. & SHEHIN, S.E. (1987). Central effect of adenosine analogs on blood pressure and heart rate in the mouse. Can. J. Cardiol., 3, 205-209.
5. BIAGGIONI, I. (1992). Contrasting excitatory and inhibitory effects of adenosine in blood pressure regulation. Hypertension, 4, 457-465.
6. BOYER, J.L., GRABER, S.G., WALDO, G.L., HARDEN, T.K. & GARRISO, J.C. (1994). Selective activation of phospholipase C by recombinant G-protein alpha and beta gamma-subunits. J. Biol. Chem., 269, 2814-2819.
7. 3 receptor-mediated hypotensive response in the rat. Eur. J. Pharmacol., 250, 185-188.
8. COLLIS, M.G. & HOURANI, S.M. (1993). Adenosine receptor subtypes. TiPS, 14, 360-366.
9. DUNWIDDIE, T.V. (1985). The physiological role of adenosine in the central nervous system. Int. Rev. Neurobiol., 27, 63-139.
10. 3 receptors mediate hypotension in the angiolensin II-supported circulation of the pithed rat. Br. J. Pharmacol., 109, 3-5.
11. 3 receptor activation in the rat. Eur. J. Pharmacol., 298, 293-297.
12. 3 receptor-mediated hypotension in the rat. Br. J. Pharmacol., 125, 945-952.
13. 3-adenosine receptors. Mediation of behavioral depressant effects. FEBS Lett., 336, 57-60.
14. KATIMS, J.J., ANNAU, Z. & SNYDER, S.H. (1983). Interactions in the behavioral effect of methylxanthines and adenosine derivatives. J. Pharm. Exp. Ther., 227, 167-173.
15. 3 receptors: pharmacological properties, species differences and receptor function. TiPS, 15, 298-306.
16. 3 adenosine receptor with widespread tissue distribution. Mol. Pharmacol., 44, 524-532.
17. MARANGOS, P.J. & BOULENGER, J.P. (1985). Basic and clinical aspects of adenosinergic neuromodulation. Neurosci. Biobehav. Rev., 9, 421-430.
18. MEYERHOF, W., MÜLLER-BRECHIN, R. & RICHER, D. (1991). Molecular cloning of a novel putative G-protein coupled receptor expressed during rat spermiogenesis. FEBS Lett., 284, 155-160.
19. PHILLIS, J.W. & WU, P.H. (1981). The role of adenosine and its nucleotides in central synaptic transmission. Prog. Neurobiol., 16, 187-239.
20. 3 adenosine receptor is the unique adenosine receptor which facilitates release of allergic mediators in mast cells. J. Biol. Chem., 268, 16887-16890.
21. 2-subtype receptor stimulation. J. Cardiovasc. Pharmacol., 25, 1001-1005.
22. STELLA, L., BERRINO, L., MAIONE, S., DE NOVELLIS, V. & ROSSI, F. (1993). Cardiovascular effects of adenosine and its analogs in anaesthetized rats. Life Sci., 57, 755-763.
23. 3 adenosine receptor. Proc. Natl. Acad. Sci. U.S.A., 89, 7432-7436.