99mTc-HMPAO SPECT in the diagnosis of brain death

Intensive Care Medicine

Volumn 24, Issue 9, 1998, Pages 911-917

  Facco, E ^a   Zucchetta, P ^a   Munari, M ^a   Baratto, F ^a   Behr, A U ^a   Gregianin, M ^a   Gerunda, A ^a   Bui, F ^a   Saladini, M ^a   Giron, G ^a  

^a UNIVERSITY OF PADOVA   (Italy)

Author keywords

Brain death; Brain injuries; Cerebrovascular circulation; EEG; SPECT

Indexed keywords

HEXAMETHYLPROPYLENE AMINE OXIME TECHNETIUM TC 99M; DIAGNOSTIC AGENT; RADIOPHARMACEUTICAL AGENT;

ADOLESCENT; ADULT; AGED; ARTICLE; BASAL GANGLION; BRAIN DEATH; BRAIN PERFUSION; BRAIN STEM; CHILD; CLINICAL ARTICLE; CLINICAL TRIAL; DRUG INDUCED DISEASE; ELECTROENCEPHALOGRAM; FEMALE; HUMAN; INFANT; INTRAVENOUS ADMINISTRATION; MALE; NEWBORN; PERSISTENT VEGETATIVE STATE; PROSPECTIVE STUDY; RADIOISOTOPE DIAGNOSIS; SCINTILLATION CAMERA; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; THALAMUS; MIDDLE AGED; PREDICTION AND FORECASTING; PRESCHOOL CHILD; SCINTISCANNING;

ADOLESCENT; ADULT; AGED; BRAIN DEATH; CHILD; CHILD, PRESCHOOL; FEMALE; HUMANS; INFANT; INFANT, NEWBORN; MALE; MIDDLE AGED; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; RADIOPHARMACEUTICALS; TECHNETIUM TC 99M EXAMETAZIME; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON;

EID: 0031593901     PISSN: 03424642     EISSN: None     Source Type: Journal    
DOI: 10.1007/s001340050689     Document Type: Article

References (37)

1. Royal Colleges and Faculties of the United Kingdom (1976) Diagnosis of brain death. BMJ 2: 1187-1188
2. President's Commission for the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research (1981) Defining death: medical, legal and ethical issues in the determination of death. US Government Printing Office
3. Report of the Medical Consultants on the Diagnosis of Death to the President's Commission on the Study of Ethical Problems in Medicine and Biomedical and Behavioral Research. Guidelines for the determination of death (1981) JAMA 246: 2184-2186
4. Ministero della Sanità (1994) Regolamento recante le modalità per l'accertamento e la certificazione di morte. Decreto 22/8/1994 n. 582
5. Wissenschaftlicher Beirat der Bundesärztekammer. "Kriterien des Hirntodes" (1991) Kriterien des Hirntodes. Dtsch Ärztebl Mitteilg 87: 2855-2860
6. Editorial (1983) Brain death criteria. Ned Tijdschr Geneeskd 127: 2293
7. Le Ministre Delegue chargé, de la Santé (1990) Decret no 90-844 du 24 septembre 1990
8. Roseklint A, Jorgensen PB (1975) Evaluation of angiographic methods in the diagnosis of brain death: correlation with local and systemic arterial pressure and intracranial pressure. Neuroradiology 7: 215-219
9. Kricheff II, Pinto RS, Korein J (1978) Angiographic findings in brain death. Ann NY Acad Sci 315: 168-173
10. Goodman JM, Heck LL, Moore BD (1985) Confirmation of brain death with portable isotope angiography: review of 204 consecutive cases. Neurosurgery 16: 492-497
11. Kosteljanetz M, Ohrstrum JK, Skjdt S, Teglbjaerg PS (1988) Clinical brain death with preserved cerebral arterial circulation. Acta Neurol Scand 78: 418-421
12. Kaufmann HH, Geisler FH, Kopitnik T, Higgins W, Stewart D (1989) Detection of brain death in barbiturate coma: the dilemma of an intracranial pulse. Neurosurgery 25: 275-277
13. Van Brunne A, Delcour C, Wery D, Richoz B, Struyven J (1989) Intravenous digital subtraction angiography. A criteria of brain death. Ann Radiol 32: 279-281
14. George MS (1991) Establishing brain death: the potential role of nuclear medicine in the search for a reliable confirmatory test. Eur J Nucl Med 18: 75-77
15. Nau R, Prange HW, Klingelhöfer J, Kukowski B, Sander D, Tchorsch R, Rittmeyer K (1992) Results of four technical investigations in fifty clinically brain dead patients. Intensive Care Med 18: 82-88
16. Powers AD, Graeber MC, Smith RR (1989) Transcranial Doppler ultrasonography in the determination of brain death. Neurosurgery 24: 884-889
17. Petty GW, Mohr JP, Pedley TA, Tatemichi TK, Lennihan L, Duterte DI, Sacco LR (1990) The role of transcranial Doppler in confirming brain death: sensitivity, specificity, and suggestions for performance and interpretation. Neurology 40: 300-303
18. 99mTc-HMPAO in brain death, persistent vegetative state and severe coma. Intensive Care Med 18: 76-81
19. Albertini A, Schonfeld S, Hiatt M, Hegyi Th (1993) Digital subtraction angiography - a new approach to brain death determination in the newborn. Pediatr Radiol 23: 195-197
20. Wilson K, Gordon L, Selby JB (1993) The diagnosis of brain death with Tc-99m HMPAO. Clin Nucl Med 18: 428-434
21. 99mTc-HMPAO and mobile gamma-camera in the diagnosis of brain death. J Nucl Biol Med 39: 14-17
22. Feri M, Ralli L, Felici M, Vanni D, Capria V (1994) Transcranial Doppler and brain death diagnosis. Crit Care Med 22: 1120-1126
23. 99mTc-HMPAO zur Diagnose des Hirntodes. Wien Med Wochenschr 140: 23-24
24. Erbengi A, Erbengi G, Cataltepe O, Topcu M, Erbas B, Aras T (1991) Brain death: determination with brain stem evoked potentials and radionuclide isotope studies. Acta Neurochir 112: 118-125
25. Valle G, Ciritella P, Bonetti MG, Dicembrino F, Perrone E, Perna GP (1993) Considerations of brain death on a SPECT cerebral perfusion study. Clin Nucl Med 18: 953-954
26. 99mTc-HMPAO cerebral scintigraphy. A reliable non-invasive method for determination of brain death. Clin Nucl Med 18: 104-109
27. 99mTc-HMPAO brain perfusion SPECT in brain death. Neuroradiology 37: 365-369
28. Pallis C (1982) ABC of brain stem death: from brain death to brain stem death. BMJ 285: 1487-1490
29. Jennett B (1982) Brain death. Intensive Care Med 8: 1-3
30. Pallis C (1983) ABC of brain stem death: the arguments about the EEG. BMJ 286: 284-287
31. Grigg MM, Kelly MA, Celesia GG, Ghobrial MW, Ross ER (1987) Electroencephalographic activity after brain death. Arch Neurol 44: 948-954
32. Buchner H, Schuchardt V (1990) Reliability of electroencephalogram in the diagnosis of brain death. Eur Neurol 30: 138-141
33. Snelling LK, Helfaer MA, Traysman RJ, Rogers M (1992) Comparison of cerebral blood flow by radionuclide cerebral angiography and by microspheres in cats. Crit Care Med 20: 395-401
34. 99mTc-HMPAO over conventional radionuclide cerebral angiography. Br J Radiol 65: 289-294
35. 99mTc-HMPAO cerebral scintigraphy in the diagnosis of brain death. Transplant Proc 23: 2491
36. Hansen AVE, Lavin PJM, Moody EB, Sandler MP (1993) False-negative cerebral radionuclide flow study, in brain death, caused by a ventricular drain. Clin Nucl Med 18: 502-505
37. Larar GN, Nagel JS (1992) Technetium-99m-HMPAO cerebral perfusion scintigraphy: considerations for timely brain death declaration. J Nucl Med 33: 2209-2213