Evaluation of the Eμ-pim-1 transgenic mouse model for short-term carcinogenicity testing

Toxicologic Pathology

Volumn 26, Issue 6, 1998, Pages 750-756

  Van Kreijl, Coen F ^a   Van Der Houven Van Oordt, C Willemien ^b,e   Kroese, E Dinant ^a   Sørensen, Ilona Kryspin ^c   Breuer, Marco L ^b   Storer, Richard D ^d  

^a NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^b LEIDEN UNIVERSITY   (Netherlands)

^c DANISH VETERINARY AND FOOD ADMINISTRATION   (Denmark)

^d MERCK RESEARCH LABORATORIES   (United States)

^e WESTERN GENERAL HOSPITAL   (United Kingdom)

Author keywords

Cancer bioassay; Carcinogen; Genotoxic; Lymphoma; Oncogenes; Tumor suppressor genes; X irradiation

Indexed keywords

MITOMYCIN C; MITOMYCIN; ONCOPROTEIN; PIM1 PROTEIN, MOUSE; PROTEIN KINASE PIM 1; PROTEIN SERINE THREONINE KINASE;

ANIMAL MODEL; ARTICLE; CANCER; CANCER RISK; CARCINOGEN TESTING; CARCINOGENICITY; CONTROLLED STUDY; DIAGNOSTIC VALUE; LYMPHOMA; MOUSE; NONHUMAN; PRIORITY JOURNAL; TRANSGENIC MOUSE; ANIMAL; C57BL MOUSE; CHEMICALLY INDUCED DISORDER; DISEASE MODEL; EVALUATION; EXPERIMENTAL NEOPLASM; GENETICS; PATHOLOGY; RADIATION INJURY; T CELL LYMPHOMA; WHOLE BODY RADIATION;

ANIMALIA; DROMAIUS NOVAEHOLLANDIAE; MUS MUSCULUS; RODENTIA;

ANIMALS; CARCINOGENICITY TESTS; DISEASE MODELS, ANIMAL; EVALUATION STUDIES; LYMPHOMA, T-CELL; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOMYCIN; NEOPLASMS, EXPERIMENTAL; NEOPLASMS, RADIATION-INDUCED; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-PIM-1; WHOLE-BODY IRRADIATION;

EID: 0031593814     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/019262339802600606     Document Type: Article

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