[3H]Rilmenidine-labelled imidazoline-receptor binding sites co-localize with [3H]2-(benzofuranyl)-2-imidazoline-labelled imidazoline-receptor binding sites and monoamine oxidase-B in rabbit, but not rat, kidney

Journal of the Autonomic Nervous System

Volumn 72, Issue 2-3, 1998, Pages 118-128

  King, Paul R ^c   Suzuki, Satoshi ^a,c   Hosseini, Ali R ^b,c   Iakovidis, Dimitri ^c   Nero, Tracy L ^c   Jackman, Graham P ^c   Louis, William J ^c   Gundlach, Andrew L ^c  

^a Owariasahi Clinic   (Japan)

^b Austin and Repatriation Med Centre ^*  (Iran)

^c UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

3H 19 6327; 3H 2 BFI; 3H Rilmenidine; 3H RO41 1049; Autoradiography; Imidazoline receptor binding site; Kidney; Monoamine oxidase; Rabbit; Rat

Indexed keywords

AMINE OXIDASE (FLAVIN CONTAINING); BENZOFURAN DERIVATIVE; IMIDAZOLINE RECEPTOR; ISOENZYME; RILMENIDINE; TRITIUM; UNINDEXED DRUG; 2 (2 BENZOFURANYL) 2 IMIDAZOLINE; 2-(2-BENZOFURANYL)-2-IMIDAZOLINE; ALPHA ADRENERGIC RECEPTOR STIMULATING AGENT; DRUG RECEPTOR; IMIDAZOLE DERIVATIVE; IMIDAZOLINE RECEPTORS; LAZABEMIDE; MONOAMINE OXIDASE INHIBITOR; N (2 AMINOETHYL) 5 (3 FLUOROPHENYL) 4 THIAZOLECARBOXAMIDE; OXAZOLE DERIVATIVE; PICOLINIC ACID DERIVATIVE; RO 41-1049; THIAZOLE DERIVATIVE;

ANIMAL TISSUE; AUTORADIOGRAPHY; COMPARATIVE STUDY; CONFERENCE PAPER; CORRELATION FUNCTION; DRUG BINDING SITE; ENZYME ACTIVE SITE; KIDNEY; KIDNEY CORTEX; KIDNEY MEDULLA; NONHUMAN; PRIORITY JOURNAL; RABBIT; RAT; RECEPTOR DENSITY; ANIMAL; ARTICLE; ENZYMOLOGY; IN VITRO STUDY; MALE; METABOLISM; SPECIES DIFFERENCE; WISTAR KYOTO RAT;

ADRENERGIC ALPHA-AGONISTS; ANIMALS; AUTORADIOGRAPHY; BENZOFURANS; IMIDAZOLES; ISOENZYMES; KIDNEY; MALE; MONOAMINE OXIDASE; MONOAMINE OXIDASE INHIBITORS; OXAZOLES; PICOLINIC ACIDS; RABBITS; RATS; RATS, INBRED WKY; RECEPTORS, DRUG; SPECIES SPECIFICITY; THIAZOLES;

EID: 0031593629     PISSN: 01651838     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1838(98)00096-4     Document Type: Conference Paper

References (30)

1. 2 imidazoline-preferring receptors. Br. J. Pharmacol. 114, 837-845.
2. 3H]2-(2-benzofuranyl)-2-imidazoline (2-BFI) in rat brain and liver: characterization, regulation and relation to monoamine oxidase enzymes. Naunyn-Schmiedeberg's Arch. Pharmacol. 356, 39-47.
3. 2 sites. J. Pharmacol. Exp. Ther. 272, 681-688.
4. Ernsberger, P., Feinland, G., Meeley, M.P., Reis, D.J., 1990. Characterization and visualization of clonidine-sensitive imidazole sites in rat kidney which recognize clonidine-displacing substance. Am. J. Hypertens. 3, 90-97.
5. Fernandes, M.H., Soares-da-Silva, P., 1992. Type A and B monoamine oxidase activities in the human and rat kidney. Acta Physiol. Scand. 145, 363-367.
6. 1-imidazoline-binding sites in rabbit proximal tubules cells. J. Cardiovasc. Pharmacol. 26 (Suppl. 2), S59-S62.
7. Harfenist, M., Soroko, F.E., McKenzie, G.M., 1978. 2-(Alkoxyaryl)-2-imidazoline monoamine oxidase inhibitors with antidepressant activity. J. Med. Chem. 21, 405-409.
8. 3H]rilmenidine binding sites in rat brain. J. Auton. Nerv. Syst. 72, 129-136.
9. 2-imidazoline receptor binding sites: studies in rabbit kidney membranes. Naunyn-Schmiedeberg's Arch. Pharmacol. 355, 131-138.
10. 3H]rilmenidine in membranes from rat cerebral cortex. Eur. J. Pharmacol. 218, 101-108.
11. 3H]rilmenidine. Brain Res. 675, 264-278.
12. 3H]imidazoline binding sites in rat kidney. Eur. J. Pharmacol. 281, 341-346.
13. Kriz, W., Bankir, L., 1988. A standard nomenclature for structures of the kidney. The Renal Commission of the International Union of Physiological Sciences (IUPS). Kidney Int. 33, 1-7.
14. 2-adrenergic binding sites in basolateral membranes from human kidney. Eur. J. Pharmacol. 206, 23-31.
15. Lanier, B., Raddatz, R., Bakthavachalam, V., Coupry, I., Neumeyer, J.L., Lanier, S.M., 1995. Structural and ligand recognition properties of imidazoline binding proteins in tissues of rat and rabbit. Mol. Pharmacol. 48, 703-710.
16. 2 receptors. Eur. J. Pharmacol. 304, 221-229.
17. Luque, J.M., Kwan, S.-W., Abell, C.W., Da Prada, M., Richards, J.G., 1995. Cellular expression of mRNAs encoding monoamine oxidases A and B in the rat central nervous system. J. Comp. Neurol. 363, 665-680.
18. Mallard, N.J., Hudson, A.L., Nutt, D.J., 1992. Characterization and autoradiographical localization of non-adrenoceptor idazoxan binding sites in the rat brain. Br. J. Pharmacol. 106, 1019-1027.
19. Michel, M.C., Insel, P.A., 1989. Are there multiple imidazoline binding sites? Trends Pharmacol. Sci. 10, 342-344.
20. 2-imidazoline receptor subtypes. Naunyn-Schmiedeberg's Arch. Pharmacol. 354, 709-716.
21. 3H]-idazoxan binding sites in the rat brain. Br. J. Pharmacol. 108, 597-603.
22. Pigini, M., Bousquet, P., Carotti, A., Dontenwill, M., Giannella, M., Moriconi, R., Piergentili, A., Quaglia, W., Tayebati, S.K., Brasili, L., 1997. Imidazoline receptors: Qualitative structure-activity relationships and discovery of tracizoline and benazoline. Two ligands with high affinity and unprecedented selectivity. Bioorg. Med. Chem. 5, 833-841.
23. Reis, D.J., Regunathan, S., Wang, H., Feinstein, D.L., Meeley, M.P., 1992. Imidazoline receptors in the nervous system. Fund. Clin. Pharmacol. 6 (Suppl. 1), 23s-29s.
24. 2-imidazoline sites) are increased in postmortem brain from patients with Alzheimer's disease. Neurosci. Lett. 160, 109-112.
25. 2 with monoamine oxidase-B sites. J. Neurochem. 61, 881-889.
26. 3H-RO19-6327 in vitro: localization and abundance of MAO-A and MAO-B in rat CNS, peripheral organs, and human brain. J. Neurosci. 12, 1977-1999.
27. Saura, J., Luque, J.M., Cesura, A.M., Da Prada, M., Chan-Palay, V., Huber, G., Löffler, J., Richards, J.G., 1994. Increased monoamine oxidase B activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography. Neuroscience 62, 15-30.
28. 2-imidazoline binding sites on monoamine oxidases. J. Biol. Chem. 270, 9856-9861.
29. Tesson, F., Prip-Buus, C., Lemoine, A., Pegorier, J.-P., Parini, A., 1991. Subcellular distribution of imidazoline-guanidinium-receptive sites in human and rabbit liver. Major localization to the mitochondrial outer membrane. J. Biol. Chem. 266, 155-160.
30. Willoughby, J., Glover, U., Sandler, M., 1988. Histochemical localisation of monoamine oxidase A and B in rat brain. J. Neural Transm. 74, 29-42.