The key of oxidative stress in acquired immune deficiency syndrome apoptosis

Medical Hypotheses

Volumn 51, Issue 2, 1998, Pages 169-173

  Romero Alvira, D ^a   Roche, E ^b  

^a HOSPITAL UNIVERSITARIO MIGUEL SERVET   (Spain)

^b UNIVERSITY OF ALICANTE   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIOXIDANT; GLYCOPROTEIN GP 120; ZIDOVUDINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; HELPER CELL; HUMAN; IMMUNOMODULATION; IMMUNOPATHOGENESIS; LYMPHOCYTE DEPLETION; OXIDATIVE STRESS; PRIORITY JOURNAL; ANIMAL; BIOLOGICAL MODEL; CD4+ T LYMPHOCYTE; IMMUNOLOGY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; REVIEW;

HUMAN IMMUNODEFICIENCY VIRUS;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ANIMALS; ANTIOXIDANTS; APOPTOSIS; CD4-POSITIVE T-LYMPHOCYTES; HUMANS; MODELS, BIOLOGICAL; OXIDATIVE STRESS;

EID: 0031593543     PISSN: 03069877     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0306-9877(98)90113-X     Document Type: Article

References (62)

1. Coffin J M. HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy. Science 1995; 267: 483-489.
2. Daar E S, Moudgil T, Meyer R D, Ho D D. Transient high levels of viremia in patients with primary human immunodeficiency virus type 1 infection. N Engl J Med 1991; 324: 961-964.
3. Gougeon M L, Montagnier L. Apoptosis in AIDS. Science 1993; 260: 1269-1270.
4. Steller H. Mechanisms and genes of cellular suicide. Science 1995; 267: 1445-1449.
5. Wertz I E, Hanley M R. Diverse molecular provocation of programmed cell death. Trends Biochem Sci 1996; 21: 359-364.
6. Hengartner M O, Horvitz H R. C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene Bcl-2. Cell 1994; 76: 665-676.
7. Kumar S. ICE-like proteases in apoptosis. Trends Biochem Sci 1995; 20: 198-202.
8. Vaux D L, Weissman I L, Kim S K. Prevention of programmed cell death in Caenorhabditis elegans by human Bcl-2. Science 1992; 258: 1955-1957.
9. Sugimoto A, Friesen P D, Rothman J H. Baculovirus p35 prevents developmentally programmed cell death and rescues a ced-9 mutant in the nematode Caenorhabditis elegans. EMBO J 1994; 13: 2023-2028.
10. Bursch W, Kleine L, Tenniswood M. The biochemistry of cell death by apoptosis. Biochem Cell Biol 1990; 68: 1071-1074.
11. Kroemer G, Petit P, Zamzami N, Vayssière J-L, Mignotte B. The biochemistry of programmed cell death. FASEB J 1995; 9: 1277-1287.
12. Thompson C B. Apoptosis in the pathogenesis and treatment of disease. Science 1995, 267: 1456-1462.
13. Weiss R A. How does HIV cause AIDS? Science 1993; 260: 1273-1277.
14. Muller W E, Schroder H C, Ushijima H, Dapper J, Bormann J. gp120 of HIV-1 induces apoptosis in rat cortical cell cultures: prevention by memantine. Eur J Pharmacol 1992; 226: 209-214.
15. Banda N K, Bernier J, Kurahara D K et al. Crosslinking CD4 by human immunodeficiency virus gp120 primes T cells for activation-induced apoptosis. J Exp Med 1992; 176: 1099-1106.
16. Li C J, Friedman D J, Wang C, Metelev V, Pardee A B. Induction of apoptosis in uninfected lymphocytes by HIV-1 Tat protein. Science 1995; 268: 429-431.
17. Laurent-Crawford A G, Krust B, Riviere Y et al. Membrane expression of HIV envelope glycoproteins triggers apoptosis in CD4 cells. AIDS Res Hum Retroviruses 1993; 9: 761-773.
18. Mastino A, Grelli S, Piacentini M et al. Correlation between induction of lymphocyte apoptosis and prostaglandin E2 production by macrophages infected with HIV. Cell Immunol 1993; 152: 120-130.
19. Malomi W, Rivabene R, Santini M T, Paradisi S, Iosi F, Donelli G. Down-modulation of CD4 antigen during programmed cell death in U937 cells. FEBS Lett 1993; 336: 335-339.
20. Merrill J E, Chen I S. HIV-1, macrophages, glial cells, and cytokines in AIDS nervous system disease. FASEB J 1991; 5: 2391-2397.
21. Makonkawkeyoon S, Limson-Pobre R N, Moreira A L, Schauf V, Kaplan G. Thalidomide inhibits the replication of human immunodeficiency virus type 1. Proc Natl Acad Sci USA 1993; 90: 5974-5978.
22. Nagata S, Golstein P. The Fas death factor. Science 1995; 267: 1449-1456.
23. Gougeon M L, Garcia S, Heeney J et al. Programmed cell death in AIDS-related HIV and SIV infections. AIDS Res Hum Retroviruses 1993; 9: 553-563.
24. Blanchard A, Montagnier L. AIDS-associated mycoplasmas. Annu Rev Microbiol 1994; 48: 687-712.
25. Harakeh S, Lirawalla R J, Pauling L. Suppression of immunodeficiency virus replication by chronically and acutely infected cells. Proc Natl Acad Sci USA 1990; 87: 7245-7249.
26. Baruchel S, Wainberg M A. The role of oxidative stress in disease progression in individuals infected by the human immunodeficiency virus. J Leukocyte Biol 1992; 52: 111-114.
27. Favier A, Sappey C, Leclerc P, Faure P, Micoud M. Antioxidant status and lipid peroxidation in patients infected with HIV. Chem-Biol Interact 1994; 91: 165-180.
28. Buhl R, Jaffe H A, Holroyd K J et al. Systemic glutathione deficiency in symptom-free HIV-seropositive individuals. Lancet 1989; 2: 1294-1296.
29. Jacobsen D W, Green R, Herbert V, Longworth D L, Rehm S. Decreased serum glutathione with normal cysteine and homocysteine levels in patients with AIDS. Clin Res 1990; 38: 556 (Abstract).
30. Javier J J, Fodyce-Baum M K, Beach R S, Gavancho M, Cabrejos C, Montero-Atienza E. Antioxidant micronutrients and immune function in HIV-1 infection. FASEB Proc 1990; 4: A940.
31. Sworkin B M, Rosenthal W S, Wormser G P, Weiss L. Selenium deficiency in the acquired immune deficiency syndrome. J Parent Ent Nutr 1986; 10: 405-407.
32. Miesel R, Zuber M. Elevated levels of xanthine oxidase in serum of patients with inflammatory and autoimmune rheumatic diseases. Inflammation 1993; 17: 551-561.
33. Gilman A G, Rall T W, Nies A S, Taylor P. The Pharmacological Basis of Therapeutics, 8th edn. New York: Pergamon Press, 1990.
34. Roederer M, Staal F J T, Raju P A, Ela W S, Herzenberg L A, Herzenberg L A. Cytokine-stimulated human immunodeficiency virus replication is inhibited by N-acetyl-L-cysteine. Proc Natl Acad Sci USA 1990; 87: 4884-4888.
35. Roederer M, Staal F J, Ela S W, Herzenberg L A, Herzenberg L A. N-acetylcysteine: potential for AIDS therapy. Pharmacology 1993; 46: 121-129.
36. Roederer M, Ela S W, Staal F J, Herzenberg L A, Herzenberg L A. N-acetylcysteine: a new approach to anti-HIV therapy. AIDS Res Hum Retroviruses 1992; 8: 209-217.
37. Resinger E C, Kern P, Ernst M et al. Inhibition of HIV progression by dithiocarbamate. Lancet 1990; 1: 679-682.
38. Brewton G W, Herst E M, Rios A, Mansell P W A, Hollinger B, Reuben J M. A pilot study of diethyldithiocarbamate in patients with acquired immune deficiency syndrome (AIDS) and AIDS-related complex. Life Sci 1989; 45: 2509-2520.
39. Hersch E M, Brewton G, Abrams D. DithioCarb sodium (Diethyl-dithio-carbamate). Therapy in patients with symptomatic HIV infection and AIDS. JAMA 1991; 265: 1538-1544.
40. Arnaudo E, Dalakas M, Shanske S, Moraes C T, DiMauro S, Schon E A. Depletion of muscle mitochondrial DNA in AIDS patients with zidovudine-induced myopathy. Lancet 1991; 337: 508-510.
41. Gogu S R, Beckman B S, Rangan S R S, Agrawal K C. Increased therapeutic efficiency of zidovudine in combination with vitamin E. Biochem Biophys Res Commun 1989; 165: 401-407.
42. Chen L H, Huang C Y, Osio Y, Fitzpatrick E A, Cohen D A. Effects of chronic alcohol feeding and murine AIDS virus infection on liver antioxidant defense system in mice. Alcoholism, Clin Exp Res 1993; 17: 1022-1028.
43. Wang Y, Watson R R. Ethanol, immune responses, and murine AIDS: the role of vitamin E as an immunostimulant and antioxidant. Alcohol 1994; 11: 75-84.
44. Resler S S. Nutrition care of AIDS patients. J Am Diet Assoc 1988; 88: 828-832.
45. Keusch G T, Farthing MJG. Nutritional aspects of AIDS. Annu Rev Nutr 1990; 10: 475-501.
46. Borellini F, He Y F, Aquino A, Yu G, Josephs S F, Glazer R I. Increased DNA binding and transcriptional activity associated with transcription factor Sp1 in K562 cells transfected with the myeloid-specific c-fes tyrosine kinase gene. J Biol Chem 1991; 266: 15850-15854.
47. Thanos D, Maniatis T. NFκB: A lesson in family values. Cell 1995; 80: 529-532.
48. Suzuki Y J, Aggarwal B B, Packer L. Alpha-lipoic acid is a potent inhibitor of NF-kappa B activation in human T cells. Biochem Biophys Res Commun 1992; 189: 1709-1715.
49. Suzuki Y J, Packer L. Inhibition of NF-kappa B activation by vitamin E derivatives. Biochem Biophys Res Commun 1993; 193: 277-283.
50. Packer L, Suzuki Y J. Vitamin E and alpha-lipoate: role in antioxidant recycling and activation of the NF-kappa B transcription factor. Mol Aspects Med 1993; 14: 229-239.
51. Chandan K S, Packer L. Antioxidant and redox regulation of gene transcription. FASEB J 1996; 10: 709-720.
52. Reed J C. Bcl-2 and the regulation of programmed cell death. J Cell Biol 1994;124: 1-6.
53. De Rossi A, Ometto L, Roncella S et al. HIV-1 induces down-regulation of bcl-2 expression and death by apoptosis of EBV-immortalized B cells: a model for a persistent 'self-limiting' HIV-1 infection. Virology 1994; 198: 234-244.
54. Akbar A N, Borthwick N, Salmon M et al. The significance of low bcl-2 expression by CD45RO T cells in normal individuals and patients with acute viral infections. The role of apoptosis in T cell memory. J Exp Med 1993;178: 427-438.
55. Steinman H M. The Bcl-2 oncoprotein functions as a prooxidant. J Biol Chem 1995; 270: 3487-3490.
56. Jacobson M D, Burne J F, King M P, Miyashita T, Reed J C, Raff M C. Bcl-2 blocks apoptosis in cells lacking mitochondrial DNA. Nature 1993; 361: 365-369.
57. Shimizu S, Eguchi Y, Kosaka H, Kamiike W, Matsuda H, Tsujimoto Y. Prevention of hypoxia-induced cell death by Bcl-2 and Bcl-xL. Nature 1995; 374: 811-813.
58. Jacobson M D, Raff M C. Programmed cell death and Bcl-2 protection in very low oxygen. Nature 1995; 374: 814-816.
59. Ranjbar S, Hannigan B M. DNA damage in human T-lymphoblastoid cell line Molt-3 induced by reactive oxygen species. Mutat Res 1993; 285: 225-228.
60. Sandstrom P A, Roberts B, Folks T M, Buttke T M. HIV gene expression enhances T cell susceptibility to hydrogen peroxideinduced apoptosis. AIDS Res Hum Retroviruses 1993; 9: 1107-1113.
61. Malorni W, Rivabene R, Santini MT, Donelli G. N-acetylcysteine inhibits apoptosis and decreases viral particles in HIV-chronically infected U937 cells. FEBS Lett 1993; 327: 75-78.
62. James J S. NAC, bronchitis drug may slow virus AIDS. Treatment News 1989; 88: 1-2.