The 5-HT4 receptor antagonist ML10375 inhibits the constitutive activity of human 5-HT(4(c)) receptor

British Journal of Pharmacology

Volumn 125, Issue 4, 1998, Pages 595-597

  Blondel, Olivier ^a,b,d   Gastineau, Monique ^a,b   Langlois, Michel ^a,c   Fischmeister, Rodolphe ^a,b  

^a Inst Signalisation Innov T   (France)

^b INSERM   (France)

^c UNIVERSITÉ PARIS SUD   (France)

^d NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

Author keywords

Human; Inverse agonist; ML10375; Serotonin 5 HT4 receptors

Indexed keywords

4 AMINO 5 CHLORO 2 METHOXYBENZOIC ACID 2 (3,5 DIMETHYLPIPERIDINO)ETHYL ESTER; ADENYLATE CYCLASE; CYCLIC AMP; PERTUSSIS TOXIN; SEROTONIN 4 ANTAGONIST; SEROTONIN 4 RECEPTOR; UNCLASSIFIED DRUG; 2-(3,5-DIMETHYLPIPERIDINO)ETHYL 4-AMINO-5-CHLORO-2-METHOXYBENZOATE; ADENYLATE CYCLASE TOXIN; AMINOBENZOIC ACID DERIVATIVE; BORDETELLA VIRULENCE FACTOR; PIPERIDINE DERIVATIVE; RECOMBINANT PROTEIN; SEROTONIN; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ANIMAL CELL; ARTICLE; ENZYME INHIBITION; NONHUMAN; PRIORITY JOURNAL; ANIMAL; CELL STRAIN COS1; DRUG EFFECT; GENETIC TRANSFECTION; HUMAN; METABOLISM;

ADENYLATE CYCLASE; ADENYLATE CYCLASE TOXIN; AMINOBENZOIC ACIDS; ANIMALS; COS CELLS; CYCLIC AMP; HUMANS; PERTUSSIS TOXIN; PIPERIDINES; RECEPTORS, SEROTONIN; RECOMBINANT PROTEINS; SEROTONIN; SEROTONIN ANTAGONISTS; TRANSFECTION; VIRULENCE FACTORS, BORDETELLA;

EID: 0031593398     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0702163     Document Type: Article

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