Diels-Alder reactions of 5,6-Dihydro-2(1H)-pyridones. Preparation of partially reduced cis-isoqninolones and cis-3,4-disubstituted piperidines

Tetrahedron Letters

Volumn 38, Issue 13, 1997, Pages 2295-2298

  Casamitjana, Núria ^a   Jorge, Angela ^a   Pérez, Carles G ^a   Bosch, Joan ^a   Espinosa, Enric ^b   Molins, Elies ^b  

^a UNIVERSITY OF BARCELONA   (Spain)

^b INSTITUT DE CIÈNCIA DE MATERIALS DE BARCELONA ICMAB CSIC   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ISOQUINOLINE DERIVATIVE; PIPERIDINE DERIVATIVE;

ARTICLE; DRUG SYNTHESIS; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0031592581     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00280-3     Document Type: Article

References (10)

1. 1. For related Diels-Alder reactions, see: a) Imbroisi, D. O.; Simpkins, N. S. J. Chem . Soc., Perkin Trans. I 1991, 1851.
2. b) Gómez-Pardo, D.; d'Angelo, J. Tetrahedron Lett. 1992, 33, 6637.
3. c) Torisawa, Y.; Nakagawa, M.; Takami, H.; Nagata, T.; Ayman Ali, M.; Hino, T. Heterocycles 1994, 39, 277.
4. d) Torisawa, Y.; Hosaka, T.; Tanabe, K.; Suzuki, N.; Motohashi, Y.; Hino, T.; Nakagawa, M. Tetrahedron 1996, 52, 10597.
5. 2. a) Grob, C. A.; Fischer, H. P.; Raundenbusch, W.; Zergeny, J. Helv. Chim. Acta 1964, 47, 1003.
6. b) Tanner, D.; Somfai, P. Tetrahedron 1988, 44, 613.
7. 3. Meyers, A. I.; Snyder, L. J. Org. Chem. 1993, 58, 36.
8. 2.
9. 5. Santelli, M.; Pons, J.-M. Lewis Acids and Selectivity in Organic Synthesis, CRC Press: Boca Raton. 1996; pp. 257-328.
10. 2Ph), 5.83-5.89 (m, 1H, 6-H), 5.90-5.97 (m, 1H, 7-H), 5.98 (d, J = 4.5 Hz, 1H, 8-H), 7.26 (s, 5H, PhH).