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Volumn 91, Issue 2, 1997, Pages 91-97

Cadmium perturbs calcium homeostasis in rat osteosarcoma (ROS 17/2.8) cells; a possible role for protein kinase C

Author keywords

Cadmium; Calcium; Calphostin C; Kinetics; Protein kinase C; ROS 17 2.8 cells

Indexed keywords

CADMIUM; CALPHOSTIN C; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR;

EID: 0031589167     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(97)03880-0     Document Type: Article
Times cited : (18)

References (38)
  • 1
    • 0024267198 scopus 로고
    • Cadmium accelerates bone loss in ovariectomized mice and fetal rat limb bones in culture
    • [1] Bhattacharyya, M.H., Whelton, B.D., Stern, P.H. and Peterson, D.P. (1988) Cadmium accelerates bone loss in ovariectomized mice and fetal rat limb bones in culture. Proc. Natl. Acad. Sci. USA 85, 8761-8765.
    • (1988) Proc. Natl. Acad. Sci. USA , vol.85 , pp. 8761-8765
    • Bhattacharyya, M.H.1    Whelton, B.D.2    Stern, P.H.3    Peterson, D.P.4
  • 2
    • 0023878775 scopus 로고
    • The effects of cadmium, copper or zinc on formation of embryonic chick bone in tissue culture
    • [2] Kaji, T., Kawatani, R., Takata, M., Hoshino, T., Miyahara, T., Kozuka, H. and Koizumi, F. (1988) The effects of cadmium, copper or zinc on formation of embryonic chick bone in tissue culture. Toxicology 50, 303-316.
    • (1988) Toxicology , vol.50 , pp. 303-316
    • Kaji, T.1    Kawatani, R.2    Takata, M.3    Hoshino, T.4    Miyahara, T.5    Kozuka, H.6    Koizumi, F.7
  • 3
    • 0018971891 scopus 로고
    • Influence of poisonous metals on bone metabolism. III. The effect of cadmium on bone resorption in tissue culture
    • [3] Miyahara, T., Miyakoshi, M., Saito, Y. and Kozuka, H. (1980) Influence of poisonous metals on bone metabolism. III. The effect of cadmium on bone resorption in tissue culture. Toxicol. Appl. Pharmacol. 55, 477-483.
    • (1980) Toxicol. Appl. Pharmacol. , vol.55 , pp. 477-483
    • Miyahara, T.1    Miyakoshi, M.2    Saito, Y.3    Kozuka, H.4
  • 4
    • 0026323464 scopus 로고
    • Cadmium block of squid calcium currents
    • [4] Chow, R.H. (1991) Cadmium block of squid calcium currents. J. Gen. Physiol. 98, 751-770.
    • (1991) J. Gen. Physiol. , vol.98 , pp. 751-770
    • Chow, R.H.1
  • 5
    • 0026716965 scopus 로고
    • Cadmium block of calcium current in frog sympathetic neurons
    • [5] Thevenod, F. and Jones, S.W. (1992) Cadmium block of calcium current in frog sympathetic neurons. Biophys. J. 63, 162-168.
    • (1992) Biophys. J. , vol.63 , pp. 162-168
    • Thevenod, F.1    Jones, S.W.2
  • 6
    • 0026048172 scopus 로고
    • Differences in cadmium and mercury uptakes by hepatocytes: Role of calcium channels
    • [6] Blazka, M.E. and Shaikh, Z.A. (1991) Differences in cadmium and mercury uptakes by hepatocytes: role of calcium channels. Toxicol. Appl. Pharmacol. 110, 355-363.
    • (1991) Toxicol. Appl. Pharmacol. , vol.110 , pp. 355-363
    • Blazka, M.E.1    Shaikh, Z.A.2
  • 8
    • 0026073423 scopus 로고
    • Replacement of calcium by cadmium ions from Caaffinity sites localized in different cytoplasmic compartments of Acanthamoeba cells
    • [8] Przelecka, A., Kluska, A.M. and Zwierzyk, M. (1991) Replacement of calcium by cadmium ions from Caaffinity sites localized in different cytoplasmic compartments of Acanthamoeba cells. Histochemistry 95, 391-395.
    • (1991) Histochemistry , vol.95 , pp. 391-395
    • Przelecka, A.1    Kluska, A.M.2    Zwierzyk, M.3
  • 9
    • 0018872612 scopus 로고
    • Calmodulin plays a pivotal role in cellular regulation
    • [9] Cheung, W.Y. (1980) Calmodulin plays a pivotal role in cellular regulation. Science 207, 19-27.
    • (1980) Science , vol.207 , pp. 19-27
    • Cheung, W.Y.1
  • 11
    • 0031105928 scopus 로고    scopus 로고
    • The effect of cadmium on cytosolic free calcium, protein kinase C (PKC) and collagen synthesis in rat osteosarcoma (ROS 17/2.8) cells
    • In Press
    • [11] Long, G.J. (1997) The effect of cadmium on cytosolic free calcium, protein kinase C (PKC) and collagen synthesis in rat osteosarcoma (ROS 17/2.8) cells. Toxicol. Appl. Pharmacol. In Press.
    • (1997) Toxicol. Appl. Pharmacol
    • Long, G.J.1
  • 12
    • 0017745032 scopus 로고
    • Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. I. Purification and characterization of an active enzyme from bovine cerebellum
    • [12] Takai, Y., Kishimoto, A., Inoue, M. and Nishizuka, Y. (1977) Studies on a cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. I. Purification and characterization of an active enzyme from bovine cerebellum. J. Biol. Chem. 252, 7603-7609.
    • (1977) J. Biol. Chem. , vol.252 , pp. 7603-7609
    • Takai, Y.1    Kishimoto, A.2    Inoue, M.3    Nishizuka, Y.4
  • 13
    • 0017716047 scopus 로고
    • Studies on the cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues
    • [13] Inoue, M., Kishimoto, A., Takai, Y. and Nishizuka, Y. (1977) Studies on the cyclic nucleotide-independent protein kinase and its proenzyme in mammalian tissues. J. Biol. Chem. 252, 7610-7616.
    • (1977) J. Biol. Chem. , vol.252 , pp. 7610-7616
    • Inoue, M.1    Kishimoto, A.2    Takai, Y.3    Nishizuka, Y.4
  • 14
    • 0023109718 scopus 로고
    • Association of protein kinase C with phospholipid vesicles
    • [14] Bazzi, M.D. and Nelsestuen, G.L. (1987) Association of protein kinase C with phospholipid vesicles. Biochemistry 26, 115-122.
    • (1987) Biochemistry , vol.26 , pp. 115-122
    • Bazzi, M.D.1    Nelsestuen, G.L.2
  • 16
    • 0023807525 scopus 로고
    • Biochemical characterization of rat brain protein kinase C isozymes
    • [16] Huang, K., Huang, F.L., Nakabayashi, H. and Yoshida, Y. (1988) Biochemical characterization of rat brain protein kinase C isozymes. J. Bsol. Chem. 263, 14839-14845.
    • (1988) J. Bsol. Chem. , vol.263 , pp. 14839-14845
    • Huang, K.1    Huang, F.L.2    Nakabayashi, H.3    Yoshida, Y.4
  • 17
    • 0018800888 scopus 로고
    • Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids
    • [17] Takai, Y., Kishimoto, A., Iwasa, Y., Kawahara, Y., Mori, T. and Nishizuka, Y. (1979) Calcium-dependent activation of a multifunctional protein kinase by membrane phospholipids. J. Biol. Chem. 254, 3692-3695.
    • (1979) J. Biol. Chem. , vol.254 , pp. 3692-3695
    • Takai, Y.1    Kishimoto, A.2    Iwasa, Y.3    Kawahara, Y.4    Mori, T.5    Nishizuka, Y.6
  • 18
    • 0001242712 scopus 로고
    • Expression of the osteoblastic phenotype
    • [18] Rodan, G.A. and Rodan, S.B. (1983) Expression of the osteoblastic phenotype. Bone Miner. Res. Annual 2, 244-285.
    • (1983) Bone Miner. Res. Annual , vol.2 , pp. 244-285
    • Rodan, G.A.1    Rodan, S.B.2
  • 21
    • 0015579498 scopus 로고
    • A simplified method for the quantitative assay of small amounts of protein in biological material
    • [21] Schacterle, G.R. and Pollack, R.L. (1973) A simplified method for the quantitative assay of small amounts of protein in biological material. Anal. Biochem. 51, 654-655.
    • (1973) Anal. Biochem. , vol.51 , pp. 654-655
    • Schacterle, G.R.1    Pollack, R.L.2
  • 22
    • 0025102674 scopus 로고
    • An overview of techniques for the measurement of calcium distribution, calcium fluxes, and cytosolic free calcium in mammaliam cells
    • [22] Borle, A.B. (1990) An overview of techniques for the measurement of calcium distribution, calcium fluxes, and cytosolic free calcium in mammaliam cells. Environ. Health Perspect. 84, 45-56.
    • (1990) Environ. Health Perspect. , vol.84 , pp. 45-56
    • Borle, A.B.1
  • 23
    • 0018091195 scopus 로고
    • Application of Akaike's information criterion in the evaluation of linear pharmacokinetic equations
    • [23] Yamaoka, K., Nakagawa, T. and Uno, J. (1978) Application of Akaike's information criterion in the evaluation of linear pharmacokinetic equations. J. Pharmacokin. Biopharm. 6, 165-175.
    • (1978) J. Pharmacokin. Biopharm. , vol.6 , pp. 165-175
    • Yamaoka, K.1    Nakagawa, T.2    Uno, J.3
  • 24
    • 0026651019 scopus 로고
    • Lead intoxication alters basal and parathyroid hormone regulated cellular calcium homeostasis in rat osteosarcoma (ROS 17/2.8) cells
    • [24] Long, G.J., Pounds, J.G. and Rosen, J.F. (1991) Lead intoxication alters basal and parathyroid hormone regulated cellular calcium homeostasis in rat osteosarcoma (ROS 17/2.8) cells. Calcif. Tissue Int. 50, 451-458.
    • (1991) Calcif. Tissue Int. , vol.50 , pp. 451-458
    • Long, G.J.1    Pounds, J.G.2    Rosen, J.F.3
  • 25
    • 0026736615 scopus 로고
    • Lead perturbs epidermal growth factor (EGF) modulation of intracellular calcium metabolism and collagen synthesis in donal rat osteoblastic (ROS 17/2.8) cells
    • [25] Long, G.J. and Rosen, J.F. (1992) Lead perturbs epidermal growth factor (EGF) modulation of intracellular calcium metabolism and collagen synthesis in donal rat osteoblastic (ROS 17/2.8) cells. Toxicol. Appl. Pharmacol. 114, 63-70.
    • (1992) Toxicol. Appl. Pharmacol. , vol.114 , pp. 63-70
    • Long, G.J.1    Rosen, J.F.2
  • 26
    • 0028588560 scopus 로고
    • Inhibitors of protein kinase C
    • [26] Gordge, P.C. and Ryves, W.J. (1994) Inhibitors of protein kinase C. Cell Signal 6, 871-882.
    • (1994) Cell Signal , vol.6 , pp. 871-882
    • Gordge, P.C.1    Ryves, W.J.2
  • 27
    • 0027416136 scopus 로고    scopus 로고
    • Staurosporin-induced morphological changes in the rat osteoblasts
    • [27] Yang, R.S., Lu, K.S., Fu, W.M., Liu, T.K. and Lin-Shiau, S.Y. (1996) Staurosporin-induced morphological changes in the rat osteoblasts. Cell. Biol. Int. 17, 75-82.
    • (1996) Cell. Biol. Int. , vol.17 , pp. 75-82
    • Yang, R.S.1    Lu, K.S.2    Fu, W.M.3    Liu, T.K.4    Lin-Shiau, S.Y.5
  • 28
    • 0028875376 scopus 로고
    • Regulation of cellular calcium through signaling cross-talk involves an intricate interplay between the actions of receptors. G-proteins, and second messengers
    • [28] Bygrave, F.L. and Roberts, H.R. (1995) Regulation of cellular calcium through signaling cross-talk involves an intricate interplay between the actions of receptors. G-proteins, and second messengers. FASEB J. 9, 1297-1303.
    • (1995) FASEB J. , vol.9 , pp. 1297-1303
    • Bygrave, F.L.1    Roberts, H.R.2
  • 31
    • 0026454587 scopus 로고
    • Measurement of intracellular cadmium with fluorescent dyes - Further evidence for the role of calcium channels in cadmium uptake
    • [31] Hinkle, P.M., Shanshala, E.D. and Nelson, E.J. (1992) Measurement of intracellular cadmium with fluorescent dyes - further evidence for the role of calcium channels in cadmium uptake. J. Biol. Chem. 267, 25553-25559.
    • (1992) J. Biol. Chem. , vol.267 , pp. 25553-25559
    • Hinkle, P.M.1    Shanshala, E.D.2    Nelson, E.J.3
  • 32
    • 0024459231 scopus 로고
    • Osteoblastic cells have L-type calcium channels
    • [32] Grygorczyk, C., Grygorczyk, R. and Ferrier, J. (1989) Osteoblastic cells have L-type calcium channels. Bone Miner. 7, 137-148.
    • (1989) Bone Miner. , vol.7 , pp. 137-148
    • Grygorczyk, C.1    Grygorczyk, R.2    Ferrier, J.3
  • 33
    • 0027102023 scopus 로고
    • Verapamil decreases cyclic load-induced calcium incorporation in ROS-17/2.8 osteosarcoma cell cultures
    • [33] Vadiakas, G.P. and Banes, A.J. (1992) Verapamil decreases cyclic load-induced calcium incorporation in ROS-17/2.8 osteosarcoma cell cultures. Matrix 12, 439-447.
    • (1992) Matrix , vol.12 , pp. 439-447
    • Vadiakas, G.P.1    Banes, A.J.2
  • 35
    • 0023822675 scopus 로고
    • 2+)-ATPase system in the osteoblast plasma membrane
    • 2+)-ATPase system in the osteoblast plasma membrane. Bone 9, 325-329.
    • (1988) Bone , vol.9 , pp. 325-329
    • Shen, V.1    Hruska, K.2    Avioli, L.V.3
  • 36
    • 0023645802 scopus 로고
    • Protein kinase C-activated calcium channel in the osteoblast-like clonal osteosarcoma cell line UMR-106
    • [36] Yamaguchi, D.T., Kleeman, C.R. and Muallem, S. (1987) Protein kinase C-activated calcium channel in the osteoblast-like clonal osteosarcoma cell line UMR-106. J. Biol. Chem. 262, 14967-14973.
    • (1987) J. Biol. Chem. , vol.262 , pp. 14967-14973
    • Yamaguchi, D.T.1    Kleeman, C.R.2    Muallem, S.3
  • 38
    • 0023944284 scopus 로고
    • Picomolar concentrations of lead stimulate brain protein kinase C
    • [38] Markovac, J. and Goldstein, G.W. (1988) Picomolar concentrations of lead stimulate brain protein kinase C. Nature 334, 71-73.
    • (1988) Nature , vol.334 , pp. 71-73
    • Markovac, J.1    Goldstein, G.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.