Exposure of tilapian fish to the pesticide lindane results in hypocellularity of the primary hematopoietic organ (pronephros) and the spleen without altering activity of phagocytic cells in these organs

Toxicology

Volumn 118, Issue 2-3, 1997, Pages 211-221

  Hart, L J ^a   Smith, S A ^a   Smith, B J ^a   Robertson, J ^a   Holladay, S D ^a  

^a VIRGINIA MARYLAND REGIONAL COLLEGE OF VETERINARY MEDICINE   (United States)

Author keywords

Fish; Hexachlorocyclohexane; Immunotoxicity; Lindane; Pronephros

Indexed keywords

LINDANE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CELL ULTRASTRUCTURE; CHEMOLUMINESCENCE; CONTROLLED STUDY; DOSE RESPONSE; FISH; FLOW CYTOMETRY; HEMATOPOIETIC CELL; IMMUNOTOXICITY; INTRAPERITONEAL DRUG ADMINISTRATION; LEUKOCYTE COUNT; MORPHOLOGY; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; SPLEEN;

ANIMALS; CARCINOGENS; CHEMILUMINESCENT MEASUREMENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; HEMATOPOIETIC STEM CELLS; INSECTICIDES; LEUKOCYTE COUNT; LINDANE; MICROSCOPY, FLUORESCENCE; MICROSPHERES; PHAGOCYTES; PHAGOCYTOSIS; SPLEEN; TETRADECANOYLPHORBOL ACETATE; TILAPIA;

ANIMALIA; TILAPIA;

EID: 0031588933     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(97)03619-6     Document Type: Article

References (29)

1. Anderson, D.P. (1990) Immunological indicators: effects of environmental stress on immune protection and disease outbreaks. Am. Fish. Soc. Symp. 8, 38-50.
2. Anderson, D.P., van Muiswinkel, W.B. and Roberson, B.S. (1984) Effects of chemically induced immune modulation on infectious diseases of fish. In: M. Kende, J. Gainer and M. Chirigos (Eds), Chemical Regulation of Immunity in Veterinary Medicine, Alan R. Liss, Inc., New York, pp. 197-211.
3. Barnett, J.B. and Rodgers, K.E. (1994) Pesticides. In: J.H. Dean, M.I. Luster, A.E. Munson and I. Kimber (Eds), Immunotoxicology and Immunopharmacology. 2nd edition, Raven Press, New York, pp. 191-208.
4. Bass, D.A., Parce, J.W., Dechatelet, L.R., Szejda, P., Seeds, M.C. and Thomas, M. (1983) Flow cytometric studies of oxidative product formation by neutrophils: A graded response to membrane stimulation. J. Immunol. 130, 1910-1917.
5. Caseda, J.E. (1993) Insecticide action at the GABA-gated chloride channel: Recognition, progress, and prospects. Arch. Insect Biochem. Physiol. 22, 13-23.
6. Cornacoff, J.B., Lauer, L.D., House, R.V., Tucker, A.N., Thurmond, L.M., Vos, J.G., Working, R.K. and Dean, J.H. (1988) Evaluation of the immunotoxicity of beta-hexachlorocyclohexane. Fundam. Appl. Toxicol. 11, 293-299.
7. Cossarini-Dunier, M. (1987) Effects of the pesticides atrazine and lindane and of manganese ions on cellular immunity of carp, Cyprinus carpio. J. Fish Biol. 31, 67-73.
8. Cossarini-Dunier, M., Monod, G., Demael, A. and Lepot, D. (1987) Effects of gamma-hexachlorocyclohexane (lindane) on carp (Cyprinus carpio). I. Effect of chronic intoxication on humoral immunity in relation with tissue pollutant levels. Ecotoxicol. Environ. Saf. 13, 339-345.
9. Das, S.N., Paul, B.N., Saxena, A.K. and Ray, P.K. (1990) Effects of in utero exposure to hexachlorocyclohexane on the developing immune system of mice. Immunopharmacol. Immunotoxicol. 12, 293-210.
10. Dean, J.H. and Murray, M.J. (1991) Toxic responses of the immune system. In: M.O. Amdur, J. Doull and C.D. Klaassen (Eds), Casarett and Doull's Toxicology, 4th edition, Pergamon Press, New York, pp. 208-333.
11. Forgue, M.F., Pinelli, E., Beraud, M., Souqual, M.C. and Pipy, B. (1990) Chemiluminescence response and arachidonic acid metabolism of macrophages induced by gamma-hexachlorocyclohexane (lindane). Food Add. Contam. 7 (Suppl. 1), S97-S99.
12. Holladay, S.D., Smith, S.A., El-Habback, H. and Caceci, T. (1996) The influence of chlorpyrifos, an organophosphate insecticide, on the immune system of tilapia (Oreochromis niloticus). J. Aquat. Anim. Health 8, 104-110.
13. Huggett, R.J., Bender, M.E. and Unger, M.A. (1987) Polynuclear aromatic hydrocarbons in the Elizabeth River, Virginia. In: K.L. Dickenson, A.W. Maki and W. Brugs (Eds), Fate and Effect of Sediment Bound Chemicals in Aquatic Systems, Pergamon Press, New York, pp. 327-341.
14. Luster, M.I., Munson, A.E., Thomas, P.T., Holsapple, M.P., Fenters, J.D., White, K.L., Lauer, L.D., Germolec, D.R., Rosenthal, G.J. and Dean, J.H. (1988) Methods evaluation: Development of a testing battery to assess chemical-induced immunotoxicity: National Toxicology Program's guidelines for immunotoxicity assessment in mice. Fundam. Appl. Toxicol. 10, 2-19.
15. Luster, M.I., Portier, C., Pair, D.G., White, K.L., Gennings, C., Munson, A.E. and Rosenthal, G.J. (1992) Risk assessment in immunotoxicology: I. Sensitivity and predictability of immune tests. Fundam. Appl. Toxicol. 18, 200-210.
16. Meera, P., Rao, P.R., Shanker, R. and Tripathi, O. (1992) Immunomodulating effects of gamma-HCH (lindane) in mice. Immunopharmacol. Immunotoxicol. 14, 261-282.
17. Padmaker, G.D., Karanth, N.G. and Karanth, N.G. (1994) Biodegradation of hexachlorocyclohexane isomers in soil and food environment. Crit. Rev. Microbiol. 20, 57-78.
18. Roux, F., Puiseux-Dao, S., Treich, I. and Fournier, E. (1978) Effect of lindane on mouse peritoneal macrophages. Toxicology 11, 259-269.
19. Saxena, M.P., Gopal, K., Jones, W. and Ray, P.K. (1992) Immune responses to Aeromonas hydrophila in catfish (Heteropneustis fossilis) exposed to cadmium and hexachlorocyclohexane. Bull. Environ. Contam. Toxicol. 48, 194-201.
20. Secombes, C.J., Fletcher, T.C., O'Flynn, J.A., Costello, M.J., Stagg, R. and Houlihan, D.F. (1991) Immunocompetence as a measure of the biological effects of sewage sludge pollution in fish. Comp. Biochem. Physiol. 100C (No. 1/2), 133-136.
21. Seeley, K.R. and Weeks-Perkins, B.A. (1991) Altered phagocytic activity of macrophages in Oyster Toadfish from a highly polluted subestuary. J. Aquat. Anim. Health 3, 224-227.
22. Warinner, J.E., Mathews, E.S. and Weeks, B.A. (1988) Preliminary investigations of the chemiluminescent response in normal and pollutant-exposed fish. Mar. Environ. Res. 24, 281-284.
23. Weeks, B.A., Warinner, J.E., Mathews, E.S. and Wishkovsky, A. (1990) Effects of toxicants on certain functions of the lymphoreticular system of fish. Pathol. Mar. Sci, 16, 369-374.
24. Weeks, B.A. and Warinner, J.E. (1986) Functional evaluation of macrophages in fish from a polluted estuary. Vet. Immunol. Immunopathol. 12, 313-320.
25. Weeks, B.A. and Warinner, J.E. (1984) Effects of toxic chemicals on macrophage phagocytosis in two estuarine fishes. Mar. Environ. Res. 14, 327-335.
26. Wester, P.W., Vethaak, A.D. and van Muiswinkel, W.B. (1994) Fish as biomarkers in immunotoxicology. Toxicology 86, 213-232.
27. Wolf, K. (1988) Fish Viruses and Viral Diseases. Cornell University Press, Ithaca, New York.
28. Zeeman, M.G. (1986) Modulation of the immune response in fish. Vet. Immunol. Immunopathol. 12, 235-241.
29. Zelikoff, J.D. (1994) Fish immunotoxicology. In: J.H. Dean, M.I. Luster, A.E. Munson and I. Kimber (Eds), Immunotoxicology and Immunopharmacology, 2nd edition, Raven Press, New York, pp. 71-96.