Localization of 16 exons to a 450-kb region involved in the autoimmune polyglandular disease type I (APECED) on human chromosome 21q22.3

DNA Research

Volumn 4, Issue 1, 1997, Pages 45-52

  Kudoh, Jun ^a   Nagamine, Kentaro ^a,b   Asakawa, Shuichi ^a   Abe, Izumi ^a   Kawasaki, Kazuhiko ^a   Maeda, Hideto ^a   Tsujimoto, Susumu ^a,c   Minoshima, Shinsei ^a   Ito, Fumiaki ^b   Shimizu, Nobuyoshi ^a  

^a KEIO UNIVERSITY   (Japan)

^b SETSUNAN UNIVERSITY   (Japan)

^c ASTELLAS PHARMA INC   (Japan)

Author keywords

APECED; BAC; Cosmid; Exon trapping

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; AUTOIMMUNE POLYENDOCRINOPATHY; BACTERIAL CHROMOSOME; CHROMOSOME 21; CHROMOSOME MAP; COSMID; EXON; GENETIC MARKER; GENETIC TRANSCRIPTION; GENETICS; HUMAN; METHODOLOGY; MOLECULAR CLONING; MOLECULAR GENETICS; NORTHERN BLOTTING; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; SEQUENCE TAGGED SITE; TISSUE DISTRIBUTION;

AMINO ACID SEQUENCE; BLOTTING, NORTHERN; CHROMOSOME MAPPING; CHROMOSOMES, BACTERIAL; CHROMOSOMES, HUMAN, PAIR 21; CLONING, MOLECULAR; COSMIDS; EXONS; GENETIC MARKERS; HUMANS; MOLECULAR SEQUENCE DATA; POLYENDOCRINOPATHIES, AUTOIMMUNE; POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY, AMINO ACID; SEQUENCE HOMOLOGY, NUCLEIC ACID; SEQUENCE TAGGED SITES; TISSUE DISTRIBUTION; TRANSCRIPTION, GENETIC;

EID: 0031588567     PISSN: 13402838     EISSN: None     Source Type: Journal    
DOI: 10.1093/dnares/4.1.45     Document Type: Article

References (7)

1. Ichikawa, H., Hosoda, F., Aral, Y., Shimizu, K., Ohira, M., and Ohki, M. 1993, A Not I restriction map of the entire long arm of human chromosome 21, Nature Genet., 4, 361-366.
2. Lindsay, S. and Bird, A. P. 1987, Use of restriction enzymes to detect potential gene sequences in mammalian DNA, Nature, 327, 336-338.
3. Lehesjoki, A.-E., Koskiniemi, M., Pandolfo, M. et al. 1992, Linkage studies in progresive myoclonus epilepsy: Unverricht-Lundborg and Lafora's diseases, Neurology, 42, 1545-1550.
4. Lehesjoki, A.-E., Koskiniemi, M., Norio, R. et al. 1993, Localization of the EPM1 gene for progresive myoclonus epilepsy on chromosome 21: Linkage disequilibrium allows high resolution mapping, Hum. Mol. Genet., 2, 1229-1234.
5. Aaltonen, J., Björses, P., Sandkuijl, L., Perheentupa, J., and Peltonen, L. 1994, An autosomal locus causing autoimmune disease: Autoimmune polyglandular disease type I assigned to chromosome 21, Nature Genet., 8, 83-87.
6. Straub, R. E., Lehner, T., Luo, Y. et al. 1994, A possible vulnerability locus for bipolar affective disorder on chromosome 21q22.3, Nature Genet., 8, 291-296.
7. Veske, A., Oehlmann, R., Younus, F. et al. 1996, Autosomal recessive non-syndromic deafness locus (DFNB8) maps on chromosome 21q22 in a large consanguineous kindred from Pakistan, Hum. Mol. Genet., 5, 165-168.