메뉴 건너뛰기




Volumn 113, Issue 1-2, 1997, Pages 9-16

Absence of p53 gene mutations in rat colon carcinomas induced through the synergistic interaction between methylazoxymethanol and X-irradiation

Author keywords

Methylazoxymethanol; Rat; X radiation

Indexed keywords

METHYLAZOXYMETHANOL; PROTEIN P53;

EID: 0031586758     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(96)04551-X     Document Type: Article
Times cited : (5)

References (47)
  • 1
    • 0011434547 scopus 로고
    • American Cancer Society, New York.
    • [1] American Cancer Society (1995) 1994 Cancer Facts and Figures. American Cancer Society, New York.
    • (1995) 1994 Cancer Facts and Figures
  • 2
    • 0025312728 scopus 로고
    • A genetic model for colorectal tumorigenesis
    • [2] Fearon, E. and Vogelstein, B. (1990) A genetic model for colorectal tumorigenesis, Cell, 61, 759-767.
    • (1990) Cell , vol.61 , pp. 759-767
    • Fearon, E.1    Vogelstein, B.2
  • 3
    • 0026744752 scopus 로고
    • Molecular genetics of colorectal carcinoma
    • [3] Hamilton, S.R. (1992) Molecular genetics of colorectal carcinoma, Cancer, 70, 1216-1221.
    • (1992) Cancer , vol.70 , pp. 1216-1221
    • Hamilton, S.R.1
  • 4
    • 0026781103 scopus 로고
    • Progression towards a molecular description of colorectal cancer development
    • [4] Fearon, E.R. and Jones, P.A. (1992) Progression towards a molecular description of colorectal cancer development, FASEB J., 6, 2783-2790.
    • (1992) FASEB J. , vol.6 , pp. 2783-2790
    • Fearon, E.R.1    Jones, P.A.2
  • 5
    • 0017695328 scopus 로고
    • Colon cancer: Its epidemiology and experimental production
    • [5] Weisburger, J.H., Reddy, B.S. and Wynder, E.L. (1977) Colon cancer: its epidemiology and experimental production, Cancer, 40, 2414-2420.
    • (1977) Cancer , vol.40 , pp. 2414-2420
    • Weisburger, J.H.1    Reddy, B.S.2    Wynder, E.L.3
  • 6
    • 0020045477 scopus 로고
    • Morphologic analogy of intestinal tract carcinogenesis in adenomatous polyposis and the azoxymethane-treated rat model
    • [6] Hamilton, S.R., Stephens, R.B., Natuzzi, E., Boitnott, J.K. and Yardley, J.H. (1982) Morphologic analogy of intestinal tract carcinogenesis in adenomatous polyposis and the azoxymethane-treated rat model, Lab. Invest., 46, 33A-34A.
    • (1982) Lab. Invest. , vol.46
    • Hamilton, S.R.1    Stephens, R.B.2    Natuzzi, E.3    Boitnott, J.K.4    Yardley, J.H.5
  • 7
    • 0022371726 scopus 로고
    • Rodents models for carcinoma of the colon
    • [7] Rogers, A.E. and Nauss, K.M. (1985) Rodents models for carcinoma of the colon, Dig. Dis. Sci., 30, 87S-102S.
    • (1985) Dig. Dis. Sci. , vol.30
    • Rogers, A.E.1    Nauss, K.M.2
  • 8
    • 0022620203 scopus 로고
    • Different autochthonous models of colorectal cancer in the rat
    • [8] Amberger, H. (1986) Different autochthonous models of colorectal cancer in the rat, J. Cancer Res. Clin. Oncol., 111, 157-159.
    • (1986) J. Cancer Res. Clin. Oncol. , vol.111 , pp. 157-159
    • Amberger, H.1
  • 9
    • 0018185248 scopus 로고
    • Induction of colonic adenocarcinoma in the rat by X-irradiation
    • [9] Deman, D.L., Kirchner, F.R. and Osborne, J.W. (1978) Induction of colonic adenocarcinoma in the rat by X-irradiation, Cancer Res., 38, 1899-1905.
    • (1978) Cancer Res. , vol.38 , pp. 1899-1905
    • Deman, D.L.1    Kirchner, F.R.2    Osborne, J.W.3
  • 10
    • 0024523902 scopus 로고
    • Apparent synergism between radiation and the carcinogen 1,2-dimethylhydrazine in the induction of colonic tumors in rats
    • [10] Sharp, J.G. and Crouse, D.A. (1989) Apparent synergism between radiation and the carcinogen 1,2-dimethylhydrazine in the induction of colonic tumors in rats, Radiat. Res., 117, 304-317.
    • (1989) Radiat. Res. , vol.117 , pp. 304-317
    • Sharp, J.G.1    Crouse, D.A.2
  • 11
    • 0027373157 scopus 로고
    • Synergistic effect of radiation on colon carcinogenesis induced by methylazoxymethanol in ACI/N rats
    • [11] Tanaka, T., Morishita, Y., Kawamori, T., Suzui, M., Sugie, S. and Mori, H. (1993) Synergistic effect of radiation on colon carcinogenesis induced by methylazoxymethanol in ACI/N rats, Jpn. J. Cancer, 84, 1031-1036.
    • (1993) Jpn. J. Cancer , vol.84 , pp. 1031-1036
    • Tanaka, T.1    Morishita, Y.2    Kawamori, T.3    Suzui, M.4    Sugie, S.5    Mori, H.6
  • 12
    • 0026080705 scopus 로고
    • Mutations in the K-ras oncogene induced by 1,2-dimethylhydrazine in preneoplastic and neoplastic rat colonic rat colonic mucosa
    • [12] Jacoby, R.F., Llor, X., Teng, B.B., Davidson, N.O. and Brasitus, T.A. (1991) Mutations in the K-ras oncogene induced by 1,2-dimethylhydrazine in preneoplastic and neoplastic rat colonic rat colonic mucosa, J. Clin. Invest., 87, 624-630.
    • (1991) J. Clin. Invest. , vol.87 , pp. 624-630
    • Jacoby, R.F.1    Llor, X.2    Teng, B.B.3    Davidson, N.O.4    Brasitus, T.A.5
  • 13
    • 0026048311 scopus 로고
    • K-ras mutations in 1,2-dimethylhydrazine-induced colonic tumors, effects of supplementary dietary calcium and vitamin D deficiency
    • [13] Llor, X., Jacoby, R.F., Teng, B.B., Davidson, N.O., Sitrin, M.D. and Brasitus, T.A. (1991) K-ras mutations in 1,2-dimethylhydrazine-induced colonic tumors, effects of supplementary dietary calcium and vitamin D deficiency, Cancer Res., 51, 4305-4309.
    • (1991) Cancer Res. , vol.51 , pp. 4305-4309
    • Llor, X.1    Jacoby, R.F.2    Teng, B.B.3    Davidson, N.O.4    Sitrin, M.D.5    Brasitus, T.A.6
  • 14
    • 0026480765 scopus 로고
    • Evidence of a ras gene mutation in azoxymethane-induced colonic aberrant crypts in Sprague-Dawley rats. Earliest recognizable precursor lesion of experimental colon cancer
    • [14] Stopera, S.A., Murphy, L.C. and Bird, R.P. (1992) Evidence of a ras gene mutation in azoxymethane-induced colonic aberrant crypts in Sprague-Dawley rats. Earliest recognizable precursor lesion of experimental colon cancer, Carcinogenesis, 13, 2081-2085.
    • (1992) Carcinogenesis , vol.13 , pp. 2081-2085
    • Stopera, S.A.1    Murphy, L.C.2    Bird, R.P.3
  • 15
    • 0028299177 scopus 로고
    • Sequential analysis of K-ras mutations in aberrant crypt foci and colonic tumors induced by azoxymethane
    • [15] Shivapurkar, N., Tang, Z.C., Andrea, F., Nasim, S., Garett, C. and Alabaster, O. (1994) Sequential analysis of K-ras mutations in aberrant crypt foci and colonic tumors induced by azoxymethane, Carcinogenesis, 15, 775-778.
    • (1994) Carcinogenesis , vol.15 , pp. 775-778
    • Shivapurkar, N.1    Tang, Z.C.2    Andrea, F.3    Nasim, S.4    Garett, C.5    Alabaster, O.6
  • 16
    • 0029121601 scopus 로고
    • Absence of p53 gene mutations in rat colon carcinomas induced by azoxymethane
    • [16] Shivapurkar, N., Belinsky, S.A., Wolf, D.C., Tang, Z.C. and Alabaster, O. (1995) Absence of p53 gene mutations in rat colon carcinomas induced by azoxymethane, Cancer Lett., 96, 63-70.
    • (1995) Cancer Lett. , vol.96 , pp. 63-70
    • Shivapurkar, N.1    Belinsky, S.A.2    Wolf, D.C.3    Tang, Z.C.4    Alabaster, O.5
  • 18
    • 0028229167 scopus 로고
    • Absence of p53 mutations in rat colon tumors induced by 2-amino-6-methyldipyridol(1,2-a:3′,2′-d) imidazole, 2-amino-3-methylimidazo-(4,5-f)quinoline, or 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine
    • [18] Makino, H., Ushijima, T., Kakiuchi, H., Onada, M., Ito, N., Sugimura, T. and Nagao, M. (1994) Absence of p53 mutations in rat colon tumors induced by 2-amino-6-methyldipyridol(1,2-a:3′,2′-d) imidazole, 2-amino-3-methylimidazo-(4,5-f)quinoline, or 2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine. Jpn. J. Cancer Res., 85, 510-514.
    • (1994) Jpn. J. Cancer Res. , vol.85 , pp. 510-514
    • Makino, H.1    Ushijima, T.2    Kakiuchi, H.3    Onada, M.4    Ito, N.5    Sugimura, T.6    Nagao, M.7
  • 19
    • 0026334385 scopus 로고
    • p53 gene mutations and abnormal retinoblastoma protein in radiation induced human sarcomas
    • [19] Brachman, D.G., Hallahan, D.E., Beckelt, M.A., Yandell, D.W. and Weichselbaum, R.R. (1991) p53 gene mutations and abnormal retinoblastoma protein in radiation induced human sarcomas, Cancer Res., 51, 6393-6396.
    • (1991) Cancer Res. , vol.51 , pp. 6393-6396
    • Brachman, D.G.1    Hallahan, D.E.2    Beckelt, M.A.3    Yandell, D.W.4    Weichselbaum, R.R.5
  • 20
    • 0026603663 scopus 로고
    • Mutations of p53 and ras genes in radon-associated lung cancer from uranium miners
    • [20] Vahakangas, K.H., Samet, J.M., Metcalf, R.A., Bennett, W.P., Lane, D.P. and Harris, C.C. (1992) Mutations of p53 and ras genes in radon-associated lung cancer from uranium miners, Lancet, 339, 576-580.
    • (1992) Lancet , vol.339 , pp. 576-580
    • Vahakangas, K.H.1    Samet, J.M.2    Metcalf, R.A.3    Bennett, W.P.4    Lane, D.P.5    Harris, C.C.6
  • 21
    • 0028177683 scopus 로고
    • p53 mutation hot spots in radon-associated lung cancer
    • [21] Taylor, J.A., Watson, M.A. and Devereux, T.R. (1994) p53 mutation hot spots in radon-associated lung cancer, Lancet, 343, 86-87.
    • (1994) Lancet , vol.343 , pp. 86-87
    • Taylor, J.A.1    Watson, M.A.2    Devereux, T.R.3
  • 22
    • 0029133175 scopus 로고
    • Latent expression of p53 mutations and radiation-induced mammary cancer
    • [22] Selvanayagam, C.S., Davis, C.M., Cornforth, M.N. and Ullrich, R.L. (1995) Latent expression of p53 mutations and radiation-induced mammary cancer, Cancer Res., 55, 3310-3317.
    • (1995) Cancer Res. , vol.55 , pp. 3310-3317
    • Selvanayagam, C.S.1    Davis, C.M.2    Cornforth, M.N.3    Ullrich, R.L.4
  • 23
    • 0023093872 scopus 로고
    • Distinctive transforming genes in X-ray-transformed mammalian cells
    • [23] Borek, C., Ong, A. and Mason, H. (1987) Distinctive transforming genes in X-ray-transformed mammalian cells Proc, Natl. Acad. Sci. USA, 84, 794-798.
    • (1987) Proc, Natl. Acad. Sci. USA , vol.84 , pp. 794-798
    • Borek, C.1    Ong, A.2    Mason, H.3
  • 24
    • 0024358108 scopus 로고
    • Detection of distinct transforming genes in X-ray induced tumors
    • [24] Jaffe, D.R. and Bowden, G.T. (1989) Detection of distinct transforming genes in X-ray induced tumors, Carcinogenesis, 10, 2243-2247.
    • (1989) Carcinogenesis , vol.10 , pp. 2243-2247
    • Jaffe, D.R.1    Bowden, G.T.2
  • 25
    • 0027096329 scopus 로고
    • Rat embryo cells immortalized with transfected oncogenes are transformed by gamma radiation
    • [25] Endlich, B., Salavati, R., Sullivan, T. and Clifton, L. (1992) Rat embryo cells immortalized with transfected oncogenes are transformed by gamma radiation, Radiat. Res., 132, 301-311.
    • (1992) Radiat. Res. , vol.132 , pp. 301-311
    • Endlich, B.1    Salavati, R.2    Sullivan, T.3    Clifton, L.4
  • 26
    • 0028324254 scopus 로고
    • Induction of stable p53 oncoprotein and c-myc overexpression in cultured normal human urothelium by radiation and N-nitrosodiethanolamine
    • [26] Mothersill, C., Harney, J. and Seymour, C.B. (1994) Induction of stable p53 oncoprotein and c-myc overexpression in cultured normal human urothelium by radiation and N-nitrosodiethanolamine, Radiat. Res., 138, 93-98.
    • (1994) Radiat. Res. , vol.138 , pp. 93-98
    • Mothersill, C.1    Harney, J.2    Seymour, C.B.3
  • 27
    • 0016374178 scopus 로고
    • Morphogenesis of chemically induced neoplasms of the colon and small intestine in rats
    • [27] Ward, J.M. (1974) Morphogenesis of chemically induced neoplasms of the colon and small intestine in rats, Lab. Invest., 30, 505-513.
    • (1974) Lab. Invest. , vol.30 , pp. 505-513
    • Ward, J.M.1
  • 28
    • 0029061363 scopus 로고
    • Low frequency of alterations in p53, K-ras and mdm2 in rat lung neoplasms induced by diesel exhaust or carbon black
    • [28] Swafford, D.S., Nikula, K.J., Mitchell, C.E. and Belinsky, S.A. (1995) Low frequency of alterations in p53, K-ras and mdm2 in rat lung neoplasms induced by diesel exhaust or carbon black, Carcinogenesis, 16, 1215-1221.
    • (1995) Carcinogenesis , vol.16 , pp. 1215-1221
    • Swafford, D.S.1    Nikula, K.J.2    Mitchell, C.E.3    Belinsky, S.A.4
  • 29
    • 0028256138 scopus 로고
    • Analysis of K-ras, p53 and c-raf-1 mutations in beryllium-induced rat lung tumors
    • [29] Nickell, C., Han, F., Finch, G. and Belinsky, S.A. (1994) Analysis of K-ras, p53 and c-raf-1 mutations in beryllium-induced rat lung tumors, Carcinogenesis, 15, 257-262.
    • (1994) Carcinogenesis , vol.15 , pp. 257-262
    • Nickell, C.1    Han, F.2    Finch, G.3    Belinsky, S.A.4
  • 31
    • 0028207349 scopus 로고
    • An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms
    • [31] Baas, I.O., Mulder, J.W.R., Offerhaus, J.A., Vogelstein, B. and Hamilton, S.R. (1994) An evaluation of six antibodies for immunohistochemistry of mutant p53 gene product in archival colorectal neoplasms, J. Pathol., 172, 5-12.
    • (1994) J. Pathol. , vol.172 , pp. 5-12
    • Baas, I.O.1    Mulder, J.W.R.2    Offerhaus, J.A.3    Vogelstein, B.4    Hamilton, S.R.5
  • 32
    • 0028299342 scopus 로고
    • P53 in tumor pathology: Can we trust immunohistochemistry?
    • [32] Hall, P.A. and Lane, D.P. (1994) P53 in tumor pathology: can we trust immunohistochemistry?, Revisited! J. Pathol., 172, 1-4.
    • (1994) Revisited! J. Pathol. , vol.172 , pp. 1-4
    • Hall, P.A.1    Lane, D.P.2
  • 33
    • 0027166013 scopus 로고
    • No allelic loss at the p53 locus in 1,2-dimethylhydrazine induced mouse colon tumors: PCR-SSCP analysis with sequence-tagged microsatellite site primers
    • [33] Okamoto, M., Ohtsu, H., Miyaki, M. and Yonekawa, H. (1993) No allelic loss at the p53 locus in 1,2-dimethylhydrazine induced mouse colon tumors: PCR-SSCP analysis with sequence-tagged microsatellite site primers, Carcinogenesis, 14, 1483-1486.
    • (1993) Carcinogenesis , vol.14 , pp. 1483-1486
    • Okamoto, M.1    Ohtsu, H.2    Miyaki, M.3    Yonekawa, H.4
  • 34
    • 0024292722 scopus 로고
    • Most human carcinomas of the exocrine pancreas contain mutant c-K-ras gene
    • [34] Almoguera, C., Shibata, D., Forrester, K., Matin, J., Arnheim, N. and Perucho, M. (1988) Most human carcinomas of the exocrine pancreas contain mutant c-K-ras gene, Cell, 53, 549-554.
    • (1988) Cell , vol.53 , pp. 549-554
    • Almoguera, C.1    Shibata, D.2    Forrester, K.3    Matin, J.4    Arnheim, N.5    Perucho, M.6
  • 36
    • 0025315142 scopus 로고
    • Activation of c-K-ras not detectable in adenomas or adenocarcinomas arising in rat pancreas
    • [36] Schefter, B.K., Zurlo, J. and Longnecker, D.S. (1990) Activation of c-K-ras not detectable in adenomas or adenocarcinomas arising in rat pancreas, Mol. Carcinogenesis, 3, 165-170.
    • (1990) Mol. Carcinogenesis , vol.3 , pp. 165-170
    • Schefter, B.K.1    Zurlo, J.2    Longnecker, D.S.3
  • 37
    • 0028044794 scopus 로고
    • Low incidence of point mutations detected in the p53 tumor suppressor gene from chemically induced rat mesenchymal tumors
    • [37] Weghorst, C.M., Dragnev, K.H., Buzard, G.S., Thome, K.L., Vadeborne, G.F., Vincent, K.A. and Rice, J.M. (1994) Low incidence of point mutations detected in the p53 tumor suppressor gene from chemically induced rat mesenchymal tumors, Cancer Res., 54, 215-219.
    • (1994) Cancer Res. , vol.54 , pp. 215-219
    • Weghorst, C.M.1    Dragnev, K.H.2    Buzard, G.S.3    Thome, K.L.4    Vadeborne, G.F.5    Vincent, K.A.6    Rice, J.M.7
  • 38
    • 0025169837 scopus 로고
    • Simian virus 40 large T antigen induces or activates a protein kinase which phosphorylates the transformation-associated protein p53
    • [38] Scheidtmann, K.H. and Haber, A. (1990) Simian virus 40 large T antigen induces or activates a protein kinase which phosphorylates the transformation-associated protein p53, J. Virol., 64, 672-679.
    • (1990) J. Virol. , vol.64 , pp. 672-679
    • Scheidtmann, K.H.1    Haber, A.2
  • 39
    • 0011433330 scopus 로고
    • The p53 gene and gene products
    • Editor: P.A. Sharp. Academic Press, San Diego, CA
    • [39] Quartin, R.S., Finlay, C.A. and Levine, A.J. (1992) The p53 gene and gene products. In: Nuclear Processes and Oncogenes, pp. 87-104. Editor: P.A. Sharp. Academic Press, San Diego, CA.
    • (1992) Nuclear Processes and Oncogenes , pp. 87-104
    • Quartin, R.S.1    Finlay, C.A.2    Levine, A.J.3
  • 42
    • 0028229441 scopus 로고
    • Mutations and expression of the p53 gene in rat bladder carcinomas and cell lines
    • [42] Asamoto, M., Mann, A.M., Macatee, T.L. and Cohen, S.M. (1994) Mutations and expression of the p53 gene in rat bladder carcinomas and cell lines, Mol. Carcinogenesis, 9, 236-244.
    • (1994) Mol. Carcinogenesis , vol.9 , pp. 236-244
    • Asamoto, M.1    Mann, A.M.2    Macatee, T.L.3    Cohen, S.M.4
  • 43
    • 0028284926 scopus 로고
    • Mutations and altered expression of p53 genes in experimental rat bladder tumor cells
    • [43] Jones, R.F., Matuszyk, J., Debiec-Rychter, M. and Wang, C.Y, (1994) Mutations and altered expression of p53 genes in experimental rat bladder tumor cells, Mol. Carcinogenesis, 9, 95-104.
    • (1994) Mol. Carcinogenesis , vol.9 , pp. 95-104
    • Jones, R.F.1    Matuszyk, J.2    Debiec-Rychter, M.3    Wang, C.Y.4
  • 45
    • 0026763408 scopus 로고
    • Rat p53 gene mutations in primary zymbal gland tumors induced by 2-amino-3-methylimidazo(4,5,-f)quinolene, a food mutagen
    • [45] Ishizaka, Y., Tsjimoto, A.A., Nakamura, T., Onda, M., Sugimura, T. and Nagao, M. (1992) Rat p53 gene mutations in primary zymbal gland tumors induced by 2-amino-3-methylimidazo(4,5,-f)quinolene, a food mutagen, Proc. Natl. Acad. Sci. USA, 89, 4850-4854.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 4850-4854
    • Ishizaka, Y.1    Tsjimoto, A.A.2    Nakamura, T.3    Onda, M.4    Sugimura, T.5    Nagao, M.6
  • 46
    • 0025892877 scopus 로고
    • Expression of p53 mutant protein(s) in dimethylnitrosamine-induced enzyme altered hepatocytes in male Fischer-344 rats
    • [46] Smith, M.L., Yeleswarapu, L., Locker, J. and Lombardi, B. (1991) Expression of p53 mutant protein(s) in dimethylnitrosamine-induced enzyme altered hepatocytes in male Fischer-344 rats, Carcinogenesis, 12, 1137-1141.
    • (1991) Carcinogenesis , vol.12 , pp. 1137-1141
    • Smith, M.L.1    Yeleswarapu, L.2    Locker, J.3    Lombardi, B.4
  • 47
    • 0028915836 scopus 로고
    • Accumulation of p53 protein in chemically induced oval cells during early stages of rodent hepatocarcinogenesis
    • [47] Wirnitzer, U., Enzmann, H., Rosenbruch, M. and Bomhard, E.M. (1995) Accumulation of p53 protein in chemically induced oval cells during early stages of rodent hepatocarcinogenesis, Carcinogenesis, 16, 697-701.
    • (1995) Carcinogenesis , vol.16 , pp. 697-701
    • Wirnitzer, U.1    Enzmann, H.2    Rosenbruch, M.3    Bomhard, E.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.