The pH dependency of protoporphyrin IX formation in cells incubated with 5-aminolevulinic acid

Cancer Letters

Volumn 113, Issue 1-2, 1997, Pages 25-29

  Bech, O ^a   Berg, K ^a   Moan, J ^a  

^a INSTITUTE OF CANCER RESEARCH   (Norway)

Author keywords

5 aminolevulinic acid; Cell survival; pH; Protoporphyrin IX

Indexed keywords

AMINOLEVULINIC ACID; PORPHOBILINOGEN DEAMINASE; PROTOPORPHYRIN;

ADENOCARCINOMA; ANIMAL CELL; ARTICLE; CHO CELL; CONTROLLED STUDY; HUMAN; HUMAN CELL; NONHUMAN; PH; PORPHYRIN METABOLISM; PRIORITY JOURNAL;

ADENOCARCINOMA; AMINOLEVULINIC ACID; ANIMALS; CELL SURVIVAL; COLONIC NEOPLASMS; CRICETINAE; FIBROBLASTS; HUMANS; HYDROGEN-ION CONCENTRATION; LUNG; PROTEINS; PROTOPORPHYRINS; TUMOR CELLS, CULTURED;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS;

EID: 0031586745     PISSN: 03043835     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0304-3835(96)04558-2     Document Type: Article

References (30)

1. [1] Moan, J. and Berg, K. (1992) Photochemotherapy of cancer: experimental research, Photochem. Photobiol., 55, 931-948.
2. [2] Eden, M., Haines, B. and Kahler, H. (1995) The pH of rat tumors measured in vivo, J. Natl. Cancer Inst., 16, 541-556.
3. [3] Gullino, P.M., Smith, S.H. and Haggerty, A.C. (1965) Modification of the acid-base status of the internal milieu of tumors, J. Natl. Cancer Inst., 34, 857-869.
4. [4] Moan, J., Smedshammer, L. and Christensen, T. (1980) Photodynamic effects on human cells exposed to light in the presence of hematoporphyrin: pH effects, Cancer Lett., 9, 327-332.
5. [5] Moan, J., Peng, Q., Evensen, J.F., Berg, K., Western, A. and Rimington, C. (1987) Photosensitizing efficiencies, tumor-and cellular uptake of different photosensitising drugs relevant for photodynamic therapy of cancer, Photochem. Photobiol., 46, 713-721.
6. [6] Calder wood, S.K. and Dickson, J.A. (1982) Inhibition of tumor blood flow at higher blood sugar levels: effects on tumor pH and hyperthermia, Natl. Cancer Inst. Monogr., 61, 713-721.
7. [7] Jain, R.K., Shah, S.A. and Finney, P.L. (1984) Continuous noninvasive monitoring of pH and temperature in rat Walker 256 carcinoma during normoglycemia and hyperglycemia, J. Natl. Cancer Inst., 73, 429-436.
8. [8] Thistletwaite, A.J., Alexander, G.A., Moylan, D.J. and Leeper, D.B. (1987) Modification of human tumor pH by elevation of blood glucose, Int. J. Radiat. Oncol. Biol. Phys., 13, 603-610.
9. [9] Thomas, J.P. and Girotti, A.W. (1989) Glucose administration augments in vivo uptake and phototoxicity of the tumor-localizing fraction of hematoporphyrin derivative, Photochem. Photobiol., 49, 241-247.
10. [10] Peng, Q., Moan, J. and Cheng, L.-S. (1991) The effect of glucose administration on the uptake of Photofrin in a human tumor xenograft, Cancer Lett., 58, 29-35.
11. [11] Kennedy, J.C., Pottier, R.H. and Pross, D.C. (1990) Photodynamic therapy with endogenous protoporphyrin IX: basic principles and present clinical experience, J. Photochem. Photobiol. B Biol., 6, 143-148.
12. [12] Wolf, P., Rieger, E. and Kerl, H. (1993) Topical photodynamic therapy with endogenous porphyrins after application of 5-aminolevulinic acid, J. Am. Acad. Dermatol., 28, 17-21.
13. [13] Grossner, L., Sroka, R., Hahn, E.G. and Ell, C. (1995) Photodynamic therapy: successful destruction of gastrointestinal cancer after oral administration of aminolevulinic acid, Gastrointest. Endosc., 41, 55-57.
14. [14] Warloe, T., Peng, Q., Heyerdahl, H., Wahre, H., Moan, J., Steen, H.B. and Giercksky, K.E. (1995) Photodynamic therapy of human tubulo-villous adenomas, Proc. SPIE, 2325, 425-436.
15. [15] Kennedy, J.C. and Pottier, R.H. (1992) Endogenous protoporphyrin IX, a clinically useful photosensitizer for photodynamic therapy, J. Photochem. Photobiol. B Biol., 14, 275-292.
16. [16] Schoenfeld, N., Epstein, O., Lahav, M., Mamet, R., Rakowski, E., Shindel, A. and Atsmon, A. (1988) Biosynthetic pathway in lymphocytes of patients with malignant lymphoproliferative disorders, Cancer Lett., 43, 43-48.
17. [17] Kondo, M., Hirota, N., Takaoka, T. and Kajiwara, M. (1993) Hemebiosynthetic activities and porphyrin accumulation in normal liver and hepatoma cell lines and rats, Cell Biol. Toxicol., 9, 95-105.
18. [18] El-Sharabasy, M.M.H., El-Wassel, A.M., Hafez, M.M. and Satin, S.A. (1992) Porphyrin metabolism in some malignant diseases, Br. J. Cancer, 65, 409-412.
19. [19] Kriegmair, M., Baumgartner, R., Kneuchel, R., Steinback, P., Ehsan, A., Lumpher, W., Hofstadter, F. and Hofstetter, A. (1994) Fluorescence detection of neoplastic urothelial lesions following intravesical installation of 5-aminolevulinic acid, Urology, 44, 836-841.
20. [20] Svanberg, K., Clemete, L.P., Clemete, M.P., Wang, I., Warloe, T., Anderson-Engels, S., Berg, R., Moan, J., Peng, Q. and Svanberg, S. (1995) Pharmacokinetic study of δ-aminolevulinic acid-induced protoporphyrin IX build-up in some malignant tumors, Proc. SPIE, 2387, 30-42.
21. [21] Noguchi, P., Wallace, R., Johnson, J., Earley, E.M., Milstien, J., Needy, C., Browne, W. and Petricciani, J. (1979) Characterization of the WiDr: a human colon carcinoma cell line, In vitro, 15, 401-408.
22. [22] Gomer, C.J., Jester, J.V., Razum, N.J., Szirth, B.C. and Murphree, L. (1985) Photodynamic therapy of intraocular tumors. Examination of hematoporphyrin derivative distribution and long-term damage in rabbit ocular tissue, Cancer Res., 45, 3718-3725.
23. [23] Bradford, M.M. (1976) A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding, Anal. Biochem., 72, 248-254.
24. [24] He, X.Z., Jaques, S.L. and Thomsen, S. (1994) In vitro cellular effects of δ-aminolevulinic acid-sensitized photodynamic therapy, Proc. SPIE, 2133, 18-27.
25. [25] Berg, K., Anholt, H., Bech, Ø. and Moan, J. (1996) The influence of iron chelators on the accumulation of protoporphyrin IX in 5-aminolevulinic acid-treated cells, Br. J. Cancer, 74, 688-697.
26. [26] Butter, A.R. and George, S. (1992) The nonenzymatic cyclic dimerisation of 5-aminolevulinic acid, Tetrahedron, 48, 7879-7886.
27. [27] Schlösser, M. and Beyersman, D. (1987) Zinc and cadmium 5-aminolevulinate dehydratase, Metal-dependent pH-profiles. Biol. Chem. Hoppe Seyler, 368, 1469-1477.
28. [28] Bottomley, S.S. and Muller-Eberhard, U. (1988) Pathophysiology of heme synthesis, Semin. Hematol., 25, 282-302.
29. [29] Anderson, P.M. and Desnick, R.J. (1980) Purification and properties of uroporphyrinogen I synthase from human erythrocytes, J. Biol. Chem., 255, 1993-1999.
30. [30] Sassa, S. (1982) Delta-aminolevulinic acid dehydratase assay, Enzyme, 28, 133-145.