Simvastatin reduces monocyte-tissue-factor expression type IIa hypercholesterolaemia

Lancet

Volumn 350, Issue 9086, 1997, Pages 1222-

  Ferro, Domenico ^a   Basili, Stefania ^a   Alessandri, Cesare ^a   Mantovani, Barbara ^a   Cordova, Corrado ^a   Violi, Francesco ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOCHOLESTEROLEMIC AGENT; SIMVASTATIN; THROMBOPLASTIN;

BIOSYNTHESIS; CLINICAL TRIAL; DIET THERAPY; DRUG ANTAGONISM; FEMALE; HUMAN; HYPERCHOLESTEROLEMIA; LETTER; MALE; METABOLISM; MIDDLE AGED; MONOCYTE; RANDOMIZED CONTROLLED TRIAL;

ANTICHOLESTEREMIC AGENTS; FEMALE; HUMANS; HYPERCHOLESTEROLEMIA; MALE; MIDDLE AGED; MONOCYTES; SIMVASTATIN; THROMBOPLASTIN;

EID: 0031586447     PISSN: 01406736     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0140-6736(05)63452-6     Document Type: Article

References (5)

1. Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 1994; 344: 1383-89.
2. Sacks FM, Pfeffer MA, Moye LA, et al. The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. N Engl J Med 1996; 335: 1001-09.
3. Vaughan CJ, Murphy MB, Buckley BM. Statins do more than just lower cholesterol. Lancet 1996; 348: 1079-82.
4. Kornberg A, Blank M, Kaufman S, Shoenfeld Y. Induction of tissue factor-like activity in monocytes by anti-cardiolipin antibodies. J Immunol 1994; 153: 1328-32.
5. Semeraro N, Biondi A, Lorenzet R, Locati D, Mantovani A, Donati MB. Direct induction of tissue factor synthesis by endotoxin in human macrophages from diverse anatomical sites. Immunology 1983; 50: 529-35.