Synthesis of C-C biaryl segment of complestatin and chloropeptin: Approach to the right band CEF-ring system of complestatin

Tetrahedron Letters

Volumn 38, Issue 12, 1997, Pages 2163-2166

  Gurjar, M K ^a   Tripathy, N K ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC AGENT; CHLOROPEPTIN; COMPLESTATIN; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CHEMICAL REACTION; CONFORMATION; DRUG STRUCTURE; DRUG SYNTHESIS; REACTION ANALYSIS;

LATEOLABRAX JAPONICUS;

EID: 0031585078     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00272-4     Document Type: Article

References (14)

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9. 7. Compound 17 was prepared in an overall yield of 70% as follows: (equation presented)
10. 3) : δ 1.43 (s, 9H), 1.92 (s, 3H), 2.25 (s, 3H), 3.06 (m, 2H), 3.44 (s, 3H), 3.65 (s, 3H), 3.86 (s, 3H), 4.24 (ABq, 2H), 4.88 (m, 2H), 5.23 (d, 1H, J = 6.6 Hz), 6.3 (m, 1H), 6.76 (s, 1H), 6.78 (s, 1H), 7.0 - 7.4 (m, 7H), 7.66 (d, 2H, J = 8.6 Hz), 8.05 (s, 1H). FABMS: 897 (M++1).
11. 9. 7-10% racemisation was observed during this step.
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