New chiral solvating agents for carboxylic acids: Discrimination of enantiotopic nuclei and binding properties

Tetrahedron Asymmetry

Volumn 8, Issue 24, 1997, Pages 3999-4002

  Bilz, Alexander ^a   Stork, Thomas ^a   Helmchen, Günter ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMIDE; CARBOXYLIC ACID; HYDRATROPIC ACID;

ARTICLE; BACTERIUM CULTURE; CALCULATION; DRUG PURIFICATION; DRUG SYNTHESIS; ENANTIOMER; METHODOLOGY; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRIORITY JOURNAL;

EID: 0031584589     PISSN: 09574166     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0957-4166(97)00586-7     Document Type: Article

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15. Association constants were determined by non-linear regression analysis of the chemical shift of the amide protons of (S)-1 and (S)-2 upon addition of acid according to C. S. Wilcox in Frontiers in Supramolecular Organic Chemistry and Photochemistry, H. J. Schneider, H. Dürr, Eds.; VCH, Weinheim, 1991, p. 123. Errors were estimated to be ±25% for all complexes.