Inhibition of Na+,K+-ATPase by 1,2,3,4,6-Penta-O-galloyl-β-D-glucose, a major constituent of both Moutan Cortex and Paeoniae Radix

Biochemical Pharmacology

Volumn 53, Issue 4, 1997, Pages 611-614

  Satoh, Kanako ^a   Nagai, Fumiko ^a   Ushiyama, Keiko ^a   Yasuda, Ichiro ^a   Seto, Takako ^a   Kano, Itsu ^a  

^a TOKYO METROPOLITAN INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

1,2,3,4,6 penta O galloyl D glucose; K+ pNPPase; Moutan Cortex; Na+,K+ ATPase; Na+,K+ ATPase inhibitor; Paeoniae Radix

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ALBIFLORIN; BENZOIC ACID; CATECHIN; GALLOYLPAEONIFLORIN; GLUCOSE PENTAGALLATE; OXYPAENIFLORIN; PAEONIFLORIN; PEONOL; PHENOL; UNCLASSIFIED DRUG;

ARTICLE; ENZYME ACTIVITY; PHOTOCHEMISTRY; PRIORITY JOURNAL;

4-NITROPHENYLPHOSPHATASE; ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; ENZYME INHIBITORS; HORSES; HYDROLYZABLE TANNINS; NA(+)-K(+)-EXCHANGING ATPASE; TANNINS;

EID: 0031581859     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(96)00828-3     Document Type: Article

References (21)

1. 1. Nishizawa M, Hayashi T, Yamagishi T, Horikoshi T, Hatakeyama Y and Honma N, Chemical studies on Paeoniae Radix (Part 5). Glucosides and gallotannin contents in Paeoniae Radix prepared from various strains of peonies. Shoyakugaku Zasshi 40: 413-433, 1986.
2. 2. Yoshikawa M and Kitagawa I, Chemical constituents of Moutan Cortex. J Tradit Sino-Jpn Med 15: 95-103, 1994.
3. 3. Yamagishi T, HPLC analysis of the constituents of Paeoniae Radix. (In Japanese). Pharm Tech Jpn 2: 269-277, 1986.
4. 4. Morita N, Shimizu M and Hayashi T, Chemical evaluation of Paeoniae Radix. J Tradit Sino-Jpn Med 12: 86-92, 1991.
5. 5. Shibutani S, Nagasawa T, Oura H, Nonaka G and Nishioka I, Effect of extract from Paeoniae Radix on urea-nitrogen concentration in rat serum. Chem Pharm Bull (Tokyo) 29: 874-878, 1981.
6. 6. Mineo S, Metori K, Renard J, Satoh T and Matsumoto H, Effects of medicinal plant extracts on sialidase activity. Yakugaku Zasshi 105: 562-568, 1985.
7. 7. Sakai Y, Ose Y, Nagase H, Kito H, Sato T, Kawai M and Mizuno M, Effects of constituents of Paeony Root on the mutagenicity of benzo[a]pyrene. Eisei Kagaku 35: 433-443, 1989.
8. 8. Yoshikawa M, Uchida E, Kawaguchi A, Kitagawa I and Yamahara J, Galloyl-oxypaeoniflorin, suffruticosides A, B, C, and D, five new antioxidative glycosides, and suffruticoside E, a paeonol glycoside, from Chinese Moutan Cortex. Chem Pharm Bull (Tokyo) 40: 2248-2250, 1992.
9. 9. Harada M and Yamashita A, Pharmacological studies on the root bark of Paeonia Moutan. I. Central effects of paeonol. Yakugaku Zasshi 89: 1205-1211, 1969.
10. 10. Harada M, Yamashita A and Aburada M, Pharmacological studies on the root bark of Paeonia Moutan. II. Anti-inflammatory effect, preventive effect on stress-induced gastric erosion, inhibitory effect on gastric juice secretion and other effects of paeonol. Yakugaku Zasshi 92: 750-756, 1972.
11. 11. Arichi S, Kubo M, Matsuda H, Tani T, Tsunaga K, Yoshikawa M and Kitagawa I, Studies on Moutan Cortex. (III). On anti-inflammatory activities (Part 1). Shoyakugaku Zasshi 33: 178-184, 1979.
12. 12. Satoh K, Nagai F, Ushiyama K and Kano I, The effects of Juzen-taiho-to and its constituent crude drugs on Na,K-ATPase and H,K-ATPase activities. J Tradit Med 12: 358-359, 1995.
13. +-ATPase activity, from Moutan Cortex. (In Japanese.) In: Proceedings (Part 2) of the 116th Meeting of the Pharmaceutical Society of Japan, Kanazawa, Japan, 27-29 March 1996 (Eds. Pharmaceutical Society of Japan), p. 184. Pharmaceutical Society of Japan, Tokyo, 1996.
14. 14. Kitagawa I, Yoshikawa M, Tsunaga T and Tani T, Studies on Moutan Cortex. (II). On the chemical constituents. Shoyakugaku Zasshi 33: 171-177, 1979.
15. 15. Yamasaki K, Kaneda M and Tanaka O, Carbon-13 NMR spectral assignments of paeoniflorm homologues with the aid of spin-lattice relaxation time. Tetrahedron Lett 44: 3965-3968, 1976.
16. 1 state. Biochem Pharmacol 44: 373-378, 1992.
17. +-pNPPase. Biochem Pharmacol 44: 993-995, 1992.
18. 18. Okuda T, Tannins, a new family of bio-active natural organic compounds. Yakugaku Zasshi 115: 81-100, 1995.
19. 19. Post RL, Kume S, Tobin T, Orcutt B and Sen AK, Flexibility of an active center in sodium-plus-potassium adenosine triphosphatase. J Gen Physiol 54: 306s-326s, 1969.
20. 20. Taniguchi K and Post RL, Synthesis of adenosine triphosphate and exchange between inorganic phosphate and adenosine triphosphate in sodium and potassium ion transport adenosine triphosphatase. J Biol Chem 250: 3010-3018, 1975.
21. 21. Nagai K and Yoshida H, Biphasic effects of nucleotides on potassium-dependent phosphatase. Biochim Biophys Acta 128: 410-412, 1966.