Regression of experimental brain tumors with 6-thioxanthine and Escherichia coli pgt gene therapy

Human Gene Therapy

Volumn 8, Issue 17, 1997, Pages 2043-2055

  Ono, Yasuhiro ^a   Ikeda, Keiro ^a   Wei, Ming X ^a   Harsh IV, Griffith R ^a   Tamiya, Takashi ^a   Chiocca, E Antonio ^a  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 THIOXANTHINE; GANCICLOVIR; PRODRUG; THYMIDINE KINASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BRAIN TUMOR; CELL PROLIFERATION; ESCHERICHIA COLI; EXPERIMENTAL NEOPLASM; GENE THERAPY; GLIOMA CELL; MOUSE; NONHUMAN; RAT; RETROVIRUS; TRANSGENE; TUMOR REGRESSION; TUMOR VOLUME;

EID: 0031581178     PISSN: 10430342     EISSN: None     Source Type: Journal    
DOI: 10.1089/hum.1997.8.17-2043     Document Type: Article

References (8)

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7. CHASIN, L.A., and URLAUB, G. (1976). Mutant alleles for hypoxanthine phosphoribosyltransferase: Codominant expression, complementation, and segregation in hybrid Chinese hamster cells. Somat. Cell Genet. 2, 453-467.
8. CHEN, S.H., SHINE, H.D., GOODMAN, J.C., GROSSMAN, R.G., and WOO, S.L.C. (1994). Gene therapy for brain tumors: Regression of experimental gliomas by adenovirus-mediated gene transfer in vivo. Proc. Natl. Acad. Sci. USA 91, 3054-3057.