Entry of Semliki forest virus into cells: Effects of concanamycin A and nigericin on viral membrane fusion and infection

Virology

Volumn 227, Issue 2, 1997, Pages 488-492

  Irurzun, Alicia ^a   Nieva, José Luis ^a,b   Carrasco, Luis ^a  

^a UNIVERSIDAD AUTÓNOMA DE MADRID   (Spain)

^b UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CONCANAMYCIN A; NIGERICIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL INVASION; CONTROLLED STUDY; ENDOSOME; MEMBRANE FUSION; NONHUMAN; PH; PRIORITY JOURNAL; SEMLIKI FOREST ALPHAVIRUS; VIRUS CELL INTERACTION;

ALPHAVIRUS; ANIMALIA; RABBIT FIBROMA VIRUS; SEMLIKI FOREST VIRUS;

EID: 0031579218     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.8340     Document Type: Article

References (43)

1. Bron, R., Wahlberg, J. M., Garoff, H., and Wilschut, J. (1993). Membrane fusion of Semliki Forest virus in a model system: Correlation between fusion kinetics and structural changes in the envelope glycoprotein. EMBO J. 12, 693-701.
2. Carrasco, L. (1994). Entry of animal viruses and macromolecules into cells. FEBS Lett. 350, 152-154.
3. Carrasco, L. (1995). Modification of membrane permeability by animal viruses. Adv. Virus Res. 45, 61-112.
4. Dröse, S., Bindseil, K. U., Bowman, E. J., Siebers, A., Zeeck, A., and Altendorf, K. (1993). Inhibitory effect of modified bafilomycins and concanamycins on P- and V-type adenosinetriphosphatases. Biochemistry 32, 3902-3906.
5. Fuller, S. D., Berriman, J. A., Butcher, S. J., and Gowen, B. E. (1995). Low pH induces swiveling of the glycoprotein heterodimers in the Semliki Forest virus spike complex. Cell 81, 715-725.
6. Galla, H. J., and Hartmann, W. (1980). Excimer-forming lipids in membrane research. Chem. Phys. Lipids 27, 199-219.
7. Gaudin, Y., Ruigrok, R. W. H., and Brunner, J. (1995). Low-pH induced conformational changes in viral fusion proteins: Implications for the fusion mechanism. J. Gen. Virol. 76, 1541-1556.
8. +-ATPases: Versatile proton pumps participating in constitutive and specialized functions of eukaryotic cells. Int. Rev. Cytol. 137, 105-137.
9. Guinea, R., and Carrasco, L. (1994a). Concanamycin A: A powerful inhibitor of enveloped animal-virus entry into cells. Biochem. Biophys. Res. Commun. 201, 1270-1278.
10. Guinea, R., and Carrasco, L. (1994b). Concanamycin A blocks influenza virus entry into cells under acidic conditions. FEBS Lett. 149, 327-330.
11. Guinea, R., and Carrasco, L. (1995). Requirement for vacuolar proton-ATPase activity during entry of influenza virus into cells. J. Virol. 69, 2306-2312.
12. Helenius, A., Kartenbeck, J., Simons, K., and Fries, E. (1980). On the entry of Semliki forest virus into BHK-21 cells. J. Cell Biol. 84, 404-420.
13. Helenius, A., Marsh, M., and White, J. (1982). Inhibition of Semliki forest virus penetration by lysosomotropic weak bases. J. Gen. Virol. 58, 47-61.
14. Helenius, A., Kielian, M., Wellsteed, J., Mellman, I., and Rudnick, G. (1985). Effects of monovalent cations on Semliki Forest virus entry into BHK-21 cells. J. Biol. Chem. 260, 5691-5697.
15. Helenius, A. (1995). Alphavirus and flavivirus glycoproteins: Structures and functions. Cell 81, 651-653.
16. Hughson, F. M. (1995). Molecular mechanisms of protein-mediated membrane fusion. Curr. Opin. Struct. Biol. 5, 507-513.
17. Irurzun, A., Sánchez-Palomino, S., Novoa, I., and Carrasco, L. (1995). Monensin and nigericin prevent the inhibition of host translation by poliovirus, without affecting p220 cleavage. J. Virol. 69, 7453-7460.
18. Kielian, M. (1995). Membrane fusion and alphavirus life cycle. Adv. Virus Res. 45, 113-151.
19. Kielian, M. C., Marsh, M., and Helenius, A. (1986). Kinetics of endosome acidification detected by mutant and wild-type Semliki Forest virus. EMBO J. 5, 3103-3109.
20. Klimjack, M. R., Jeffrey, S., and Kielian, M. (1994). Membrane and protein interactions of a soluble form of the Semliki Forest virus fusion protein. J. Virol. 68, 6940-6946.
21. Lamb, R. A. (1993). Paramyxovirus fusion: A hypothesis for changes. Virology 197, 1-11.
22. Marsh, M., Wellsteed, J., Kern, H., Harms, E., and Helenius, A. (1982). Monensin inhibits Semliki Forest virus penetration into culture cells. Proc. Natl. Acad. Sci. USA 79, 5297-5301.
23. Marsh, M., Bolzau, E., and Helenius, A. (1983). Penetration of Semliki Forest virus from acidic prelysosomal vacuoles. Cell 32, 931-940.
24. Marsh, M., and Helenius, A. (1989). Virus entry into animal cells. Adv. Virus. Res. 36, 107-151.
25. Mellman, I., Fuchs, R., and Helenius, A. (1986). Acidification of the endocytic and exocytic pathways. Annu. Rev. Biochem. 55, 663-700.
26. +-ATPases. Trends Biochem. Sci. 14, 113-116.
27. Nieva, J. L., Bron, R., Corver, J., and Wilschut, J. (1994). Membrane fusion of Semliki Forest virus requires sphingolipids in the target membrane. EMBO J. 13, 2797-2804.
28. Ohkuma, S., and Poole, B. (1978). Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents. Proc. Natl. Acad. Sci. USA 75, 3327-3331.
29. Pal, R., Barenholz, Y., and Wagner, R. R. (1988). Pyrene phospholipid as a biological fluorescent probe for studying fusion of virus membrane with liposomes. Biochemistry 27, 30-36.
30. Perez, L., and Carrasco, L. (1994). Involvement of the vacuolar ATPase in animal virus entry. J. Gen. Virol. 75, 2595-2606.
31. Perez, L., Irurzun, A., and Carrasco, L. (1994). Action of BFA on translation in SFV-infected HeLa cells and doubly infected with poliovirus. J. Gen. Virol. 75, 2197-2203.
32. Pressman, B. C. (1976). Biological applications of ionophores. Annu. Rev. Biochem. 45, 501-530.
33. Schlegel, R., Willingham, M., and Pastan, I. (1981). Monensin blocks endocytosis of vesicular stomatitis virus. Biochem. Biophys. Res. Commun. 102, 992-998.
34. Schneider, D. L. (1987). The proton pump ATPase of lysosomes and related organelles of the vacuolar apparatus. Biochim. Biophys. Acta 895, 1-10.
35. Seglen, P. O. (1983). Inhibitors of lysosomal function. Methods Enzymol. 96, 737-764.
36. Stegman, T., Schoen, P., Bron, R., Wey, J., Bartoldus, I., Ortiz, A., Nieva, J. L., and Wilschut, J. (1993). Evaluation of viral membrane fusion assays: Comparison of the octadecylrhodamine dequenching assay with the pyrene excimer assay. Biochemistry 32, 11330-11337.
37. Vénien-Bryan, C., and Fuller, S. D. (1994). The organization of the spike complex of Semliki Forest virus. J. Mol. Bol. 236, 572-583.
38. Wahlberg, J. M., Bron, R., Wilschut, J., and Garoff, H. (1992). Membrane fusion of Semliki Forest virus involves homotrimers of the fusion protein. J. Virol. 66, 7309-7318.
39. Wahlberg, J. M., and Garoff, H. (1992). Membrane fusion process of Semliki Forest virus. I: Low pH-induced rearrangement in spike protein quaternary structure precedes virus penetration into cells. J. Cell Biol. 116, 339-348.
40. White, J., and Helenius, A. (1980). pH-dependent fusion between the Semliki Forest virus membrane and liposomes. Proc. Natl. Acad. Sci. USA 77, 3273-3277.
41. White, J., Kartenbeck, J., and Helenius, A. (1980). Fusion of Semliki forest virus with the plasma membrane can be induced by low pH. J. Cell Biol. 87, 264-272.
42. White, J. M. (1990). Viral and cellular membrane fusion proteins. Annu. Rev. Physiol. 52, 675-697.
43. Zeuzem, S., Feick, P., Zimmermann, P., Haase, W., Kahn, R. A., and Schulz, I. (1992). Intravesicular acidification correlates with binding of ADP-ribosylation factor to microsomal membranes. Proc. Natl. Acad. Sci. USA 89, 6619-6623.