Findings about the cholinergic basal forebrain using immunotoxin to the nerve growth factor receptor

Annals of the New York Academy of Sciences

Volumn 835, Issue , 1997, Pages 20-29

  Wiley, Ronald G ^a,b  

^a VANDERBILT UNIVERSITY   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLINE ACETYLTRANSFERASE; IMMUNOTOXIN; NERVE GROWTH FACTOR RECEPTOR; SAPORIN;

ANIMAL CELL; ANIMAL EXPERIMENT; BRAIN NERVE CELL; CHOLINERGIC NERVE CELL; CONFERENCE PAPER; CONTROLLED STUDY; FOREBRAIN; NEUROANATOMY; NEUROCHEMISTRY; NONHUMAN;

ANIMALIA;

EID: 0031578927     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1997.tb48615.x     Document Type: Conference Paper

References (15)

1. COYLE, J. T., D. L. PRICE & M. R. DELONG. 1983. Alzheimer's disease: A disorder of cortical cholinergic innervation. Science 219: 1184-1190.
2. SHIOSAKA, S. 1992. Attempts to make models for Alzheimer's disease. Neurosci. Res. 13: 237-255.
3. BALL, M. J. 1982. Alzheimer's disease: A challenging engima. Arch. Pathol. Lab. Med. 106: 157-162.
4. JARRARD, L. E., A. LEVY, J. L. MEYERHOFF & G. J. KANT. 1985. Intracerebral injections of AF64A: An animal model of Alzheimer's disease? Ann. N. Y. Acad. Sci. 444: 520-522.
5. SMITH, G. 1988. Animal models of Alzheimer's disease: Experimental cholinergic denervation. Brain Res. 472: 103-118.
6. THAL, L. J., R. J. MANDEL, R. D. TERRY, G. BUZSAKI & F. H. GAGE. 1990. Nucleus basalis lesions fail to induce senile plaques in the rat. Exp. Neurol. 108: 88-90.
7. WENK, G. L. 1990. Animal models of Alzheimer's disease: Are they valid and useful? Acta Neurobiol. Exp. (Warsz.) 50: 219-223.
8. FISHER, A. & I. HANIN. 1986. Potential animal models for senile dementia of Alzheimer's type, with emphasis on AF64A-induced cholinotoxicity. Annu. Rev. Pharmacol. Toxicol. 26: 161-181.
9. SARTER, M. 1987. Animal models of brain ageing and dementia. Compr. Gerontol. A 1: 4-15.
10. PEPEU, G., I. M. PEPEU & F. CASAMENTI. 1990. The validity of animal models in the search for drugs for the aging brain. Drug Des. Deliv. 7: 1-10.
11. WALSH, T. J. & J. J. CHROBAK. 1991. Animal models of Alzheimer's disease: Role of hippocampal cholinergic systems in working memory. In Brain, Emotion and Cognition. L. Dalhowski & C. F. Flaherty, Eds.: 347-378. Lawrence Erlbaum Associates. Hillsdale, NJ.
12. DUNNETT, S. B., I. G. WHISHAW, G. H. JONES & S. T. BUNCH. 1987. Behavioural, biochemical and histochemical effects of different neurotoxic amino acids injected into nucleus basalis magnocellularis of rats. Neuroscience 20: 653-669.
13. FIBIGER, H. C. 1991. Cholinergic mechanisms in learning, memory and dementia: A review of recent evidence. Trends Neurosci. 14: 220-223.
14. DUNNETT, S. B., B. J. EVERITT & T. W. ROBBINS. 1991. The basal forebrain-cortical cholinergic system: Interpreting the functional consequences of excitotoxic lesions. Trends Neurosci. 14: 494-501.
15. DUNNETT, S. B. & H. C. FIBIGER. 1993. Role of forebrain cholinergic systems in learning and memory: Relevance to the cognitive deficits of aging and Alzheimer's dementia. Prog. Brain Res. 98: 413-420.