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Volumn 104, Issue 1-2, 1997, Pages 209-213

Convergent control of serotonin transporter expression by glucocorticoids and cocaine in fetal and neonatal rat brain

Author keywords

Brain development; Cocaine; Dexamethasone; Glucocorticoid; Paroxetine; Serotonin; Transpo rter

Indexed keywords

COCAINE; DEXAMETHASONE; GLUCOCORTICOID; PAROXETINE; SEROTONIN; SEROTONIN TRANSPORTER;

EID: 0031578872     PISSN: 01653806     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-3806(97)00144-2     Document Type: Article
Times cited : (11)

References (50)
  • 2
    • 0025611152 scopus 로고
    • Cocaine acutely inhibits DNA synthesis in developing rat brain regions: Evidence for direct actions
    • [2] T. Anderson-Brown, T.A. Slotkin, F.J. Seidler, Cocaine acutely inhibits DNA synthesis in developing rat brain regions: evidence for direct actions, Brain Res. 537 (1990) 197-202.
    • (1990) Brain Res. , vol.537 , pp. 197-202
    • Anderson-Brown, T.1    Slotkin, T.A.2    Seidler, F.J.3
  • 3
    • 0001913633 scopus 로고
    • Glucocorticoid induced teratologies of the nervous system
    • J. Yanai (Eds.), Elsevier, Amsterdam
    • [3] M.C. Bohn, Glucocorticoid induced teratologies of the nervous system, in: J. Yanai (Eds.), Neurobehavioral Teratology, Elsevier, Amsterdam, 1984, pp. 365-387.
    • (1984) Neurobehavioral Teratology , pp. 365-387
    • Bohn, M.C.1
  • 4
    • 0016794293 scopus 로고
    • Adrenal, plasma and urinary corticosteroids during single or repeated administration of morphine in cats
    • [4] J. Borrell, I. Lloréns, S. Borrell, Adrenal, plasma and urinary corticosteroids during single or repeated administration of morphine in cats, Eur. J. Pharmacol. 31 (1975) 237-242.
    • (1975) Eur. J. Pharmacol. , vol.31 , pp. 237-242
    • Borrell, J.1    Lloréns, I.2    Borrell, S.3
  • 6
    • 0023604663 scopus 로고
    • Perinatal neurotoxicology of psychotropic drugs
    • [6] V. Cuomo, Perinatal neurotoxicology of psychotropic drugs, Trends Pharmacol. Sci. 8 (1987) 346-350.
    • (1987) Trends Pharmacol. Sci. , vol.8 , pp. 346-350
    • Cuomo, V.1
  • 7
    • 0024348239 scopus 로고
    • Long-term neurochemical and neurobehavioral consequences of cocaine use during pregnancy
    • [7] D.L. Dow-Edwards, Long-term neurochemical and neurobehavioral consequences of cocaine use during pregnancy, Ann. NY Acad. Sci. 562 (1989) 280-289.
    • (1989) Ann. NY Acad. Sci. , vol.562 , pp. 280-289
    • Dow-Edwards, D.L.1
  • 8
    • 0029951489 scopus 로고    scopus 로고
    • Modification of acoustic startle reactivity by cocaine administration during the postnatal period: Comparison with a specific serotonin reuptake inhibitor
    • [8] D.L. Dow-Edwards, Modification of acoustic startle reactivity by cocaine administration during the postnatal period: comparison with a specific serotonin reuptake inhibitor, Neurotoxicol. Teratol. 18 (1996) 289-296.
    • (1996) Neurotoxicol. Teratol. , vol.18 , pp. 289-296
    • Dow-Edwards, D.L.1
  • 9
    • 0027483588 scopus 로고
    • Neurochemical development of the raphe after continuous prenatal cocaine exposure
    • [9] E.M. Factor, R.P. Hart, G.M. Jonakait, Neurochemical development of the raphe after continuous prenatal cocaine exposure, Brain Res. Bull. 31 (1993) 49-56.
    • (1993) Brain Res. Bull. , vol.31 , pp. 49-56
    • Factor, E.M.1    Hart, R.P.2    Jonakait, G.M.3
  • 10
    • 0029666198 scopus 로고    scopus 로고
    • 3H]cyanoimipramine for quantitative measurement of serotonin transporter sites in human brain
    • 3H]cyanoimipramine for quantitative measurement of serotonin transporter sites in human brain, Neuropsychopharmacology 14 (1996) 309-323.
    • (1996) Neuropsychopharmacology , vol.14 , pp. 309-323
    • Gurevich, E.V.1    Joyce, J.H.2
  • 12
    • 0010749650 scopus 로고
    • Do serotonin and other neurotransmitters exert a trophic influence on the immature brain?
    • [12] M. Hamon, S. Bourgoin, C. Chanez, F. De Vitry, Do serotonin and other neurotransmitters exert a trophic influence on the immature brain?, Dev. Neurobiol. 12 (1989) 171-183.
    • (1989) Dev. Neurobiol. , vol.12 , pp. 171-183
    • Hamon, M.1    Bourgoin, S.2    Chanez, C.3    De Vitry, F.4
  • 13
    • 0025811154 scopus 로고
    • Differential effects of prenatal and postnatal ACTH or nicotine exposure on 5-HT high affinity uptake in the neonatal rat brain
    • [13] J.A. King, M. Davila-Garcia, E.C. Azmitia, F.L. Strand, Differential effects of prenatal and postnatal ACTH or nicotine exposure on 5-HT high affinity uptake in the neonatal rat brain, Int. J. Dev. Neurosci. 9 (1991) 281-286.
    • (1991) Int. J. Dev. Neurosci. , vol.9 , pp. 281-286
    • King, J.A.1    Davila-Garcia, M.2    Azmitia, E.C.3    Strand, F.L.4
  • 14
    • 0026330832 scopus 로고
    • Ischemia contributes to adverse effects of cocaine on brain development: Suppression of ornithine decarboxylase activity in neonatal rat
    • [14] S.M. Koegler, F.J. Seidler, J.R. Spencer, T.A. Slotkin, Ischemia contributes to adverse effects of cocaine on brain development: suppression of ornithine decarboxylase activity in neonatal rat, Brain Res. Bull. 27 (1991) 829-834.
    • (1991) Brain Res. Bull. , vol.27 , pp. 829-834
    • Koegler, S.M.1    Seidler, F.J.2    Spencer, J.R.3    Slotkin, T.A.4
  • 15
    • 0021903260 scopus 로고
    • Roles for neurotransmitters in development: Possible interaction with drugs during the fetal and neonatal periods
    • M. Marois (Eds.), Alan R. Liss, New York
    • [15] J.M. Lauder, Roles for neurotransmitters in development: possible interaction with drugs during the fetal and neonatal periods, in: M. Marois (Eds.), Prevention of Physical and Mental Congenital Defects, Alan R. Liss, New York, 1985, pp. 375-380.
    • (1985) Prevention of Physical and Mental Congenital Defects , pp. 375-380
    • Lauder, J.M.1
  • 16
    • 0018233676 scopus 로고
    • Serotonin as a differentiation signal in early neurogenesis
    • [16] J.M. Lauder, H. Krebs, Serotonin as a differentiation signal in early neurogenesis, Dev. Neurosci. 1 (1978) 15-30.
    • (1978) Dev. Neurosci. , vol.1 , pp. 15-30
    • Lauder, J.M.1    Krebs, H.2
  • 19
    • 0030460121 scopus 로고    scopus 로고
    • Monoamine transporters and the neurobehavioral teratology of cocaine
    • [19] J.S. Meyer, L.P. Shearman, L.M. Collins, Monoamine transporters and the neurobehavioral teratology of cocaine, Pharmacol. Biochem. Behav. 55 (1996) 585-593.
    • (1996) Pharmacol. Biochem. Behav. , vol.55 , pp. 585-593
    • Meyer, J.S.1    Shearman, L.P.2    Collins, L.M.3
  • 20
    • 0027436119 scopus 로고
    • Cocaine binding sites in fetal rat brain: Implications for prenatal cocaine action
    • [20] J.S. Meyer, L.P. Shearman, L.M. Collins, R.L. Maguire, Cocaine binding sites in fetal rat brain: implications for prenatal cocaine action, Psychopharmacology 112 (1993) 445-451.
    • (1993) Psychopharmacology , vol.112 , pp. 445-451
    • Meyer, J.S.1    Shearman, L.P.2    Collins, L.M.3    Maguire, R.L.4
  • 21
    • 0023402610 scopus 로고
    • Cocaine induced secretion of ACTH, β-endorphin and corticosterone
    • [21] R.L. Moldow, A.J. Fischman, Cocaine induced secretion of ACTH, β-endorphin and corticosterone, Peptides 8 (1987) 819-822.
    • (1987) Peptides , vol.8 , pp. 819-822
    • Moldow, R.L.1    Fischman, A.J.2
  • 22
    • 0025917799 scopus 로고
    • 3H-paroxetine binding to the serotonin transporter is insensitive to changes in central serotonergic innervation in the rat
    • 3H-paroxetine binding to the serotonin transporter is insensitive to changes in central serotonergic innervation in the rat, Psychiat. Res. 38 (1991) 97-104.
    • (1991) Psychiat. Res. , vol.38 , pp. 97-104
    • Moret, C.1    Briley, M.2
  • 23
    • 0024404923 scopus 로고
    • Prenatal dexamethasone administration disrupts the pattern of cellular development in rat lung
    • [23] H.A. Navarro, E.M. Kudlacz, J.P. Eylers, T.A. Slotkin, Prenatal dexamethasone administration disrupts the pattern of cellular development in rat lung, Teratology 40 (1989) 433-438.
    • (1989) Teratology , vol.40 , pp. 433-438
    • Navarro, H.A.1    Kudlacz, E.M.2    Eylers, J.P.3    Slotkin, T.A.4
  • 24
    • 0023711915 scopus 로고
    • Effects of prenatal dexamethasone on development of ornithine decarboxylase activity in brain and peripheral tissues of rats
    • [24] H.A. Navarro, J. Lachowicz, J. Bartolome, W.L. Whitmore, T.A. Slotkin, Effects of prenatal dexamethasone on development of ornithine decarboxylase activity in brain and peripheral tissues of rats, Pediatr. Res. 24 (1988) 465-469.
    • (1988) Pediatr. Res. , vol.24 , pp. 465-469
    • Navarro, H.A.1    Lachowicz, J.2    Bartolome, J.3    Whitmore, W.L.4    Slotkin, T.A.5
  • 25
    • 0028986978 scopus 로고
    • Potential mechanisms of cocaine-induced developmental neurotoxicity: A minireview
    • [25] G.D. Olsen, Potential mechanisms of cocaine-induced developmental neurotoxicity: a minireview, Neurotoxicology 16 (1995) 159-167.
    • (1995) Neurotoxicology , vol.16 , pp. 159-167
    • Olsen, G.D.1
  • 26
    • 0026013428 scopus 로고
    • Cocaine in pregnancy: The effect of maternal administration of cocaine on the maternal and fetal pituitary-adrenal axis
    • [26] J.R. Owiny, M.T. Jones, D. Sadowsky, T. Myers, A. Massmann, P.W. Nathanielsz, Cocaine in pregnancy: the effect of maternal administration of cocaine on the maternal and fetal pituitary-adrenal axis, Am. J. Obstet. Gynecol. 164 (1991) 658-663.
    • (1991) Am. J. Obstet. Gynecol. , vol.164 , pp. 658-663
    • Owiny, J.R.1    Jones, M.T.2    Sadowsky, D.3    Myers, T.4    Massmann, A.5    Nathanielsz, P.W.6
  • 27
    • 0029779834 scopus 로고    scopus 로고
    • Exposure to threshold doses of nicotine in utero: 3. Augmentation of the prolactin and ACTH response to 8-OH DPAT by desipramine treatment is compromised in adult male offspring
    • [27] R.E. Poland, P. Lutchman-Singh, D. Au, S. McGeoy, M. Que, S. Acosta, J.T. McCracken, Exposure to threshold doses of nicotine in utero: 3. Augmentation of the prolactin and ACTH response to 8-OH DPAT by desipramine treatment is compromised in adult male offspring, Neurotoxicology 17 (1996) 351-358.
    • (1996) Neurotoxicology , vol.17 , pp. 351-358
    • Poland, R.E.1    Lutchman-Singh, P.2    Au, D.3    McGeoy, S.4    Que, M.5    Acosta, S.6    McCracken, J.T.7
  • 28
    • 0028871375 scopus 로고
    • Stress-induced sensitization and glucocorticoids: 2. Sensitization of the increase in extracellular dopamine induced by cocaine depends on stress-induced corticosterone secretion
    • [28] F. Rougepont, M. Marinelli, M. LeMoal, H. Simon, P.V. Piazza, Stress-induced sensitization and glucocorticoids: 2. sensitization of the increase in extracellular dopamine induced by cocaine depends on stress-induced corticosterone secretion, J. Neurosci. 15 (1995) 7189-7195.
    • (1995) J. Neurosci. , vol.15 , pp. 7189-7195
    • Rougepont, F.1    Marinelli, M.2    LeMoal, M.3    Simon, H.4    Piazza, P.V.5
  • 29
    • 0016609460 scopus 로고
    • Nicotine-induced stimulation of steroidogenesis in adrenocortical cells of the cat
    • [29] R.P. Rubin, W. Warner, Nicotine-induced stimulation of steroidogenesis in adrenocortical cells of the cat, Br. J. Pharmacol. 53 (1975) 357-362.
    • (1975) Br. J. Pharmacol. , vol.53 , pp. 357-362
    • Rubin, R.P.1    Warner, W.2
  • 30
    • 0027390639 scopus 로고
    • Prenatal cocaine and cell development in rat brain regions: Effects on ornithine decarboxylase and macro-molecules
    • [30] F.J. Seidler, T.A. Slotkin, Prenatal cocaine and cell development in rat brain regions: effects on ornithine decarboxylase and macro-molecules, Brain Res. Bull. 30 (1993) 91-99.
    • (1993) Brain Res. Bull. , vol.30 , pp. 91-99
    • Seidler, F.J.1    Slotkin, T.A.2
  • 31
    • 0030302506 scopus 로고    scopus 로고
    • Characterization and localization of [I-125]RTI-55-labeled cocaine binding sites in fetal and adult rat brain
    • [31] L.P. Shearman, L.M. Collins, J.S. Meyer, Characterization and localization of [I-125]RTI-55-labeled cocaine binding sites in fetal and adult rat brain, J. Pharmacol. Exp. Ther. 277 (1996) 1770-1783.
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 1770-1783
    • Shearman, L.P.1    Collins, L.M.2    Meyer, J.S.3
  • 33
    • 0021988259 scopus 로고
    • Effects of prenatal exposure to tricyclic antidepressants on adrenergic responses in progeny
    • [33] J.W. Simpkins, F.P. Field, G. Torosian, E.E. Soltis, Effects of prenatal exposure to tricyclic antidepressants on adrenergic responses in progeny, Dev. Pharmacol. Ther. 8 (1985) 17-33.
    • (1985) Dev. Pharmacol. Ther. , vol.8 , pp. 17-33
    • Simpkins, J.W.1    Field, F.P.2    Torosian, G.3    Soltis, E.E.4
  • 34
    • 0019957739 scopus 로고
    • Development of polyamine and biogenic amine systems in brains and hearts of neonatal rats given dexamethasone: Role of biochemical alterations in cellular maturation for producing deficits in ontogeny of neurotransmitter levels, uptake, storage and turnover
    • [34] T.A. Slotkin, G. Barnes, C. Lau, F.J. Seidler, P. Trepanier, S.J. Weigel, W.L. Whitmore, Development of polyamine and biogenic amine systems in brains and hearts of neonatal rats given dexamethasone: role of biochemical alterations in cellular maturation for producing deficits in ontogeny of neurotransmitter levels, uptake, storage and turnover, J. Pharmacol. Exp. Ther. 221 (1982) 686-693.
    • (1982) J. Pharmacol. Exp. Ther. , vol.221 , pp. 686-693
    • Slotkin, T.A.1    Barnes, G.2    Lau, C.3    Seidler, F.J.4    Trepanier, P.5    Weigel, S.J.6    Whitmore, W.L.7
  • 35
    • 0029996834 scopus 로고    scopus 로고
    • Programming of brainstem serotonin transporter development by prenatal glucocorticoids
    • [35] T.A. Slotkin, G.A. Barnes, E.C. McCook, F.J. Seidler, Programming of brainstem serotonin transporter development by prenatal glucocorticoids, Dev. Brain Res. 93 (1996) 155-161.
    • (1996) Dev. Brain Res. , vol.93 , pp. 155-161
    • Slotkin, T.A.1    Barnes, G.A.2    McCook, E.C.3    Seidler, F.J.4
  • 36
    • 0026663876 scopus 로고
    • Glucocorticoids and the development of neuronal function: Effects of prenatal dexamethasone exposure on central noradrenergic activity
    • [36] T.A. Slotkin, S.E. Lappi, E.C. McCook, M.I. Tayyeb, J.P. Eylers, F.J. Seidler, Glucocorticoids and the development of neuronal function: effects of prenatal dexamethasone exposure on central noradrenergic activity, Biol. Neonate 61 (1992) 326-336.
    • (1992) Biol. Neonate , vol.61 , pp. 326-336
    • Slotkin, T.A.1    Lappi, S.E.2    McCook, E.C.3    Tayyeb, M.I.4    Eylers, J.P.5    Seidler, F.J.6
  • 38
    • 0031040838 scopus 로고    scopus 로고
    • Serotonin transporter expression in rat brain regions and blood platelets: Aging and glucocorticoid effects
    • [38] T.A. Slotkin, E.C. McCook, J.C. Ritchie, B.J. Carroll, F.J. Seidler, Serotonin transporter expression in rat brain regions and blood platelets: aging and glucocorticoid effects, Biol. Psychiatry 41 (1997) 172-183.
    • (1997) Biol. Psychiatry , vol.41 , pp. 172-183
    • Slotkin, T.A.1    McCook, E.C.2    Ritchie, J.C.3    Carroll, B.J.4    Seidler, F.J.5
  • 39
    • 0030273348 scopus 로고    scopus 로고
    • Do glucocorticoids contribute to the abnormalities in serotonin transporter expression and function seen in depression? an animal model
    • [39] T.A. Slotkin, E.C. McCook, J.C. Ritchie, F.J. Seidler, Do glucocorticoids contribute to the abnormalities in serotonin transporter expression and function seen in depression? An animal model, Biol. Psychiatry 40 (1996) 576-684.
    • (1996) Biol. Psychiatry , vol.40 , pp. 576-684
    • Slotkin, T.A.1    McCook, E.C.2    Ritchie, J.C.3    Seidler, F.J.4
  • 40
    • 0027180085 scopus 로고
    • Glucocorticoids regulate the development of intracellular signaling: Enhanced forebrain adenylate cyclase catalytic subunit activity after fetal dexamethasone exposure
    • [40] T.A. Slotkin, E.C. McCook, F.J. Seidler, Glucocorticoids regulate the development of intracellular signaling: enhanced forebrain adenylate cyclase catalytic subunit activity after fetal dexamethasone exposure, Brain Res. Bull. 32 (1993) 359-364.
    • (1993) Brain Res. Bull. , vol.32 , pp. 359-364
    • Slotkin, T.A.1    McCook, E.C.2    Seidler, F.J.3
  • 41
    • 0025884139 scopus 로고
    • Fetal dexamethasone exposure impairs cellular development in neonatal rat heart and kidney: Effects on DNA and protein in whole tissues
    • [41] T.A. Slotkin, F.J. Seidler, RJ.. Kavlock, J.V. Bartolome, Fetal dexamethasone exposure impairs cellular development in neonatal rat heart and kidney: effects on DNA and protein in whole tissues, Teratology 43 (1991) 301-306.
    • (1991) Teratology , vol.43 , pp. 301-306
    • Slotkin, T.A.1    Seidler, F.J.2    Kavlock, R.J.3    Bartolome, J.V.4
  • 42
    • 0018761628 scopus 로고
    • Perinatal methadone addiction affects brain synaptic development of biogenic amine systems in the rat
    • [42] T.A. Slotkin, W.L. Whitmore, M. Salvaggio, F.J. Seidler, Perinatal methadone addiction affects brain synaptic development of biogenic amine systems in the rat, Life Sci. 24 (1979) 1223-1230.
    • (1979) Life Sci. , vol.24 , pp. 1223-1230
    • Slotkin, T.A.1    Whitmore, W.L.2    Salvaggio, M.3    Seidler, F.J.4
  • 43
    • 0027248086 scopus 로고
    • Prenatal cocaine increases striatal serotonin innervation without altering the patch/matrix organization of intrinsic cell types
    • [43] A.M. Snyder-Keller, R.W. Keller, Prenatal cocaine increases striatal serotonin innervation without altering the patch/matrix organization of intrinsic cell types, Dev. Brain Res. 74 (1993) 261-267.
    • (1993) Dev. Brain Res. , vol.74 , pp. 261-267
    • Snyder-Keller, A.M.1    Keller, R.W.2
  • 44
    • 0024563168 scopus 로고
    • Fetal and maternal brain and plasma levels of cocaine and benzoylecgonine following chronic subcutaneous administration of cocaine during gestation in rats
    • [44] L.P. Spear, N.A. Frambes, C.L. Kirstein, Fetal and maternal brain and plasma levels of cocaine and benzoylecgonine following chronic subcutaneous administration of cocaine during gestation in rats, Psychopharmacology 97 (1989) 427-431.
    • (1989) Psychopharmacology , vol.97 , pp. 427-431
    • Spear, L.P.1    Frambes, N.A.2    Kirstein, C.L.3
  • 45
    • 0024334215 scopus 로고
    • Cocaine effects on the developing nervous system: Behavioral, psychopharmacological and neurochemical studies
    • [45] L.P. Spear, C.L. Kirstein, N.A. Frambes, Cocaine effects on the developing nervous system: behavioral, psychopharmacological and neurochemical studies, Ann. NY Acad. Sci. 562 (1989) 290-307.
    • (1989) Ann. NY Acad. Sci. , vol.562 , pp. 290-307
    • Spear, L.P.1    Kirstein, C.L.2    Frambes, N.A.3
  • 46
    • 0015576568 scopus 로고
    • Catecholamine concentrations in discrete areas of the rat brain after the pre- and neonatal administration of phencyclidine and imipramine
    • [46] S.R. Tonge, Catecholamine concentrations in discrete areas of the rat brain after the pre- and neonatal administration of phencyclidine and imipramine, J. Pharm. Pharmacol. 25 (1973) 164-166.
    • (1973) J. Pharm. Pharmacol. , vol.25 , pp. 164-166
    • Tonge, S.R.1
  • 47
    • 0029893639 scopus 로고    scopus 로고
    • Evolutionary ancient roles of serotonin: Long-lasting regulation of activity and development
    • [47] K. Turlejski, Evolutionary ancient roles of serotonin: long-lasting regulation of activity and development, Acta Neurobiol. Exp. 56 (1996) 619-636.
    • (1996) Acta Neurobiol. Exp. , vol.56 , pp. 619-636
    • Turlejski, K.1
  • 48
    • 0016679511 scopus 로고
    • The role of adrenal catecholamines in the release of corticosterone and fatty acids by nicotine in the rat
    • [48] D.M. Turner, The role of adrenal catecholamines in the release of corticosterone and fatty acids by nicotine in the rat, Res. Comm. Chem. Pathol. Pharmacol. 12 (1975) 645-655.
    • (1975) Res. Comm. Chem. Pathol. Pharmacol. , vol.12 , pp. 645-655
    • Turner, D.M.1
  • 49
    • 0029988022 scopus 로고    scopus 로고
    • Normal development of tyrosine hydroxylase and serotonin immunoreactive fibers innervating anterior cingulate cortex and visual cortex in rabbits exposed prenatally to cocaine
    • [49] X.H. Wang, P. Levitt, A.O. Jenkins, E.H. Murphy, Normal development of tyrosine hydroxylase and serotonin immunoreactive fibers innervating anterior cingulate cortex and visual cortex in rabbits exposed prenatally to cocaine, Brain Res. 715 (1996) 221-224.
    • (1996) Brain Res. , vol.715 , pp. 221-224
    • Wang, X.H.1    Levitt, P.2    Jenkins, A.O.3    Murphy, E.H.4
  • 50
    • 0026357342 scopus 로고
    • Role of serotonin and other neurotransmitter receptors in brain development: Basis for developmental pharmacology
    • [50] P.M. Whitaker-Azmitia, Role of serotonin and other neurotransmitter receptors in brain development: basis for developmental pharmacology, Pharmacol. Rev. 43 (1991) 553-561.
    • (1991) Pharmacol. Rev. , vol.43 , pp. 553-561
    • Whitaker-Azmitia, P.M.1


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