A pivotal role of nitric oxide in migraine pain

Annals of the New York Academy of Sciences

Volumn 835, Issue , 1997, Pages 363-372

  Thomsen, Lars Lykke ^a,b   Olesen, Jes ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b GLOSTRUP UNIVERSITY HOSPITAL   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; ARGININE; GLYCERYL TRINITRATE; GUANYLATE CYCLASE; HISTAMINE; ISOSORBIDE 5 NITRATE; MEPYRAMINE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; RESERPINE;

BLOOD BRAIN BARRIER; CLINICAL TRIAL; CONFERENCE PAPER; ENZYME ACTIVATION; HEADACHE; HUMAN; MIDDLE CEREBRAL ARTERY; MIGRAINE; NERVE ENDING; NONHUMAN; SENSORY NERVE; THROMBOCYTE AGGREGATION; VASCULAR ENDOTHELIUM; VASODILATATION;

EID: 0031578870     PISSN: 00778923     EISSN: None     Source Type: Book Series    
DOI: 10.1111/j.1749-6632.1997.tb48642.x     Document Type: Conference Paper

References (19)

1. FURCHGOTT R. F. & J. V. ZAWADZKI. 1980. The obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature 288: 373-376.
2. PALMER, R. M. J., A. G. FERRIGE & S. MONCADA. 1987. Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor. Nature 327: 524-526.
3. OLESEN, J., L. L. THOMSEN & H. K. IVERSEN. 1994. Nitric oxide is a key molecule in migraine and other vascular headaches. Trends Pharmacol. Sci. 15: 149-153.
4. THOMSEN, L. L., H. K. IVERSEN, L. H. LASSEN & J. OLESEN. 1994. The role of nitric oxide in migraine pain: Therapeutic implications. CNS Drugs 2: 417-422.
5. OLESEN, J., L. L. THOMSEN, L. H. LASSEN & I. JANSEN-OLESEN. 1995. The nitric oxide hypothesis of migraine and other vascular headaches. Cephalalgia 15: 94-100.
6. KIECHLE, F. L. & T. MALINSKI. 1993. Nitric oxide biochemistry, pathophysiology and detection. Am. J. Clin. Pathol. 100: 567-575.
7. WENNMALM, Å. & A PETERSON. 1991. Analysis of nitrite as a marker for endotheliumderived relaxing factor in bilogical fluids using electron paramagnetic resonance spectrometry. J. Cardiovasc. Pharmacol. 17: s34-s40.
8. KNOWLES, R. G. & S. MONCADA. 1994. Nitric oxide synthases in mammals. Biochem. J. 298: 249-258.
9. LÜSCHER, T. F. & P. M. VANHOUTTE. 1990. The endothelium: Modulator of cardiovascular functions. CRC Press. Boca Raton, FL.
10. GARTHWAITE, J. 1993. Nitric oxide signalling in the nervous system. The Neurosciences 5: 171-180.
11. GRAY, D. W. & I. MARSHALL. 1992. Human alpha-calcitonin gene-related peptide stimulates adenylate cyclase and guanylate cyclase and relaxes rat thoracic aorta by releasing nitric oxide. Br. J. Pharmacol. 107: 691-696.
12. TODA, N. 1990. Mechanism underlying responses to histamine of isolated monkey and human cerebral arteries. Am. J. Physiol. 258: H311-H317.
13. AYAJIKI, K., T. OKAMURA & N. TODA. 1992. Involvement of nitric oxide in endotheliumdependent, phasic relaxation caused by histamine in monkey cerebral arteries. Jpn. J. Pharmacol. 60: 357-362.
14. 1c-like receptors. Naunyn-Schmiedeberg's Arch. Pharmakol. 347: 471-477.
15. DE NUCCI, G., R. THOMAS, P. D'ORLEANS-JUSTE, E. ANTUNES, C. WALDER, T. D. WARNER & J. R. VANE. 1988. Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium derived relaxing factor. Proc. Natl. Acad. Sci. USA 85: 9797-9800.
16. STUEHR, D. J., H. J. CHO, N. S. KWON, M. F. WEISE & C. F. NATHAN. 1991. Purification and characterization of the cytokine-induced macrophage nitric oxide synthase: An FAD- and FMN-containing flavoprotein. Proc. Natl. Acad. Sci. USA 88: 7773-7777.
17. BUSSE, R. & A. MÜLSCH. 1990. Induction of nitric oxide synthase by cytokines in vascular smooth muscle cells. FEES Lett. 275: 87-90.
18. WALLACE, M. N. & S. K. BISLAND. 1994. NADPH-diaphorase activity in activated astrocytes represents inducible nitric oxide synthase. Neuroscience 59: 905-919.
19. MONCADA, S., R. M. J. PALMER & E. A. HIGGS. 1991. Nitric oxide: Physiology, pathophysiology and pharmacology. Pharmacol. Rev. 43: 109-142.