RNA editing and alternative splicing generate mRNA transcript diversity from the Drosophila 4f-rnp locus

Gene

Volumn 204, Issue 1-2, 1997, Pages 267-276

  Petschek, Jane P ^a   Scheckelhoff, Mark R ^a   Mermer, Matthew J ^b   Vaughn, Jack C ^a  

^a MIAMI UNIVERSITY   (United States)

^b MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

4f rnp; Alternative splicing; Drosophila; RNA editing; RNA binding protein

Indexed keywords

ADENOSINE DEAMINASE; COMPLEMENTARY DNA; MESSENGER RNA;

ALTERNATIVE RNA SPLICING; AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONSENSUS SEQUENCE; CONTROLLED STUDY; DROSOPHILA MELANOGASTER; FEMALE; GENE EXPRESSION REGULATION; GENE LOCUS; INTRON; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN RNA BINDING; RNA EDITING; STOP CODON;

ALTERNATIVE SPLICING; AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; BINDING SITES; CONSENSUS SEQUENCE; DNA, COMPLEMENTARY; DROSOPHILA; DROSOPHILA PROTEINS; GENES, INSECT; MOLECULAR SEQUENCE DATA; RESTRICTION MAPPING; RIBONUCLEOPROTEINS; RNA EDITING; RNA, MESSENGER; RNA-BINDING PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; VARIATION (GENETICS);

ANIMALIA; ARACHNIDA; DROSOPHILA MELANOGASTER; HEXAPODA; MELANOGASTER;

EID: 0031578712     PISSN: 03781119     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-1119(97)00465-4     Document Type: Article

References (42)

1. Adam S.A., Nakagawa T., Swanson M.S., Woodruff T.K., Dreyfuss G. mRNA polyadenylate-binding protein: gene isolation and sequencing and identification of a ribonucleoprotein consensus sequence. Mol. Cell. Biol. 6:1986;2932-2943.
2. Bass, B.L., 1993. RNA editing: new uses for old players in the RNA world. In: Gesteland, R.F., Atkins, J.F. (Eds.), The RNA World. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY, pp. 383-418.
3. Bass B.L. RNA editing and hypermutation by adenosine deamination. Trends Biochem. Sci. 22:1997;157-162.
4. Bell L., Maine E., Schedl P., Cline T. Sex-lethal, a Drosophila sex determination switch gene, exhibits sex-specific RNA splicing and sequence similarity to RNA binding proteins. Cell. 55:1988;1037-1046.
5. Biggin M.D., Bickel S., Bensen M., Pirotta V., Tijian R. Zeste encodes a sequence-specific transcription factor that activates the Ultrabithorax promoter in vitro. Cell. 53:1988;713-722.
6. Blochlinger K., Bodmer R., Jack J., Jan J.Y., Jan Y.N. Primary structure and expression of a product from cut, a locus involved in specifying sensory organ identity in Drosophila. Nature. 333:1988;629-635.
7. Brown N., Kafatos F. Functional cDNA libraries from Drosophila embryos. J. Mol. Biol. 203:1988;425-437.
8. Burd C., Dreyfuss G. Conserved structures and diversity of functions of RNA binding proteins. Science. 265:1994;615-621.
9. Burns C.M., Chu H., Rueter S.M., Hutchinson L.K., Canton H., Sanders-Bush E., Emeson R.B. Regulation of serotonin-2C receptor G-protein coupling by RNA editing. Nature. 387:1997;303-308.
10. Cavener D.R. Comparison of the consensus sequence flanking translational start sites in Drosophila and vertebrates. Nucleic Acids Res. 15:1987;1353-1361.
11. Chabot, B., 1994. Synthesis and purification of RNA substrates. In: Higgins, S.J., Hames, B.D. (Eds.), RNA Processing: A Practical Approach. IRL Press, Oxford, pp. 1-29.
12. Herbert A. RNA editing, introns and evolution. Trends Genet. 12:1996;6-9.
13. Hess K.A., Simone A.A., Petschek J.P. Spatial and temporal expression of 4f-rnp gene in Drosophila melanogaster. Differentiation. 61:1996;103-111.
14. Itoh N., Slemmon J.R., Hawke D.H., Williamson R., Morita E., Itakura K., Roberts E., Shively J.E., Crawford G.D., Salvaterre P.M. Cloning of Drosophila choline acetyltransferase cDNA. Proc. Natl. Acad. Sci. USA. 83:1986;4081-4085.
15. Kelley R.L. Initial organization of the Drosophila dorsoventral axis depends on an RNA-binding protein encoded by squid. Genes Dev. 7:1993;948-960.
16. Kimelman D., Kirschner M.W. An antisense mRNA directs the covalent modification of the transcript encoding fibroblast growth factor in Xenopus oocytes. Cell. 59:1989;687-696.
17. Lantz V., Chang J.S., Horabin J.I., Bopp D., Schedl P. The Drosophila orb RNA-binding protein is required for the formation of the egg chamber and establishment of polarity. Genes Dev. 8:1994;598-613.
18. Lomeli H., Mosbacher J., Melcher T., Hoger T., Geiger J., Kuner T., Monyer H., Higuchi M., Bach A., Seeburg P.H. Control of kinetic properties of AMPA receptor channels by nuclear RNA editing. Science. 266:1994;1709-1713.
19. MacDougall C., Harbison D., Bownes M. The developmental consequences of alternate splicing in sex determination and differentiation in Drosophila. Dev. Biol. 172:1995;353-376.
20. Mount S.M., Burks C., Hertz G., Stormo G.D., White O., Fields C. Splicing signals in Drosophila: intron size, information content, and consensus sequences. Nucleic Acids Res. 20:1992;4255-4262.
21. Nagai K., Oubridge C., Jessen T.H., Li J., Evans P.R. Crystal structure of the RNA-binding domain of the U1 small nuclear ribonucleoprotein A. Nature. 348:1990;515-520.
22. Nagai K., Oubridge C., Ito N., Avis J., Evans P. The RNP domain: a sequence specific RNA-binding domain involved in processing and transport of RNA. Trends Biochem. Sci. 20:1995;235-240.
23. O'Hare K., Levis R., Rubin G.M. Transcription of the white locus in Drosophila melanogaster. Proc. Natl. Acad. Sci. USA. 80:1983;6917-6921.
24. Pavlus, J.E., 1996. Characterization of two lethal mutations induced by chromosomal rearrangements involving the 4f-rnp locus of Drosophila melanogaster. Thesis, Miami University.
25. Petschek J.P., Mermer M.J., Scheckelhoff M.R., Simone A.A., Vaughn J.C. RNA editing in Drosophila 4f-rnp gene nuclear transcripts by multiple A-to-G conversions. J. Mol. Biol. 259:1996;885-890.
26. Pirotta V., Manet E., Hardon E., Bickel S.E., Bensen M. Strucutre and sequence of the Drosophila zeste gene. EMBO J. 6:1987;791-799.
27. Polson A.G., Bass B.L. Preferential selection of adenosines for modification by double-stranded RNA adenosine deaminase. EMBO J. 13:1994;5701-5711.
28. Polson A.G., Bass B.L., Casey J.L. RNA editing of hepatitis delta virus antigenome by dsRNA-adenosine deaminase. Nature. 380:1996;454-456.
29. Poole S.J., Kauvar L.M., Drees B., Kornberg T. The engrailed locus of Drosophila: structural analysis of an embryonic transcript. Cell. 40:1985;37-43.
30. Rave N., Crkvenjakov R., Boedtker H. Identification of procollagen mRNAs transferred to diazobenzyloxymethyl paper from formaldehyde agarose gels. Nucleic Acids Res. 6:1979;3559-3567.
31. Robinow S., Campos A.R., Yao K.M., White K. The elav gene product of Drosophila, required in neurons, has three RNP consensus motifs. Science. 242:1988;1570-1572.
32. Saccomanno L., Bass B.L. The cytoplasm of Xenopus oocytes contains a factor that protects double-stranded RNA from adenosine-to-inosine modification. Mol. Cell. Biol. 14:1994;5425-5432.
33. Sambrook, J., Fritsch, E.F., Maniatis, T., 1989. Molecular Cloning: A Laboratory Manual. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY.
34. Sanger F., Nicklen S., Coulson A.R. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA. 74:1977;5463-5467.
35. Scott J. A place in the world for RNA editing. Cell. 81:1995;833-836.
36. Slegers H., Mettrie R., Kondo M. Evidence for a cytoplasmic translational inhibitor RNA in Artemia salina gastrula embryos. FEBS Lett. 80:1977;390-394.
37. Sollner-Webb B., Reeder R. The nucleotide sequence of the initiation and termination sites for ribosomal RNA transcription in X. laevis. Cell. 18:1979;485-499.
38. Sommer B., Kohler M., Sprengel R., Seeburg P.H. RNA editing in brain controls a determinant of ion flow in glutamate-gated channels. Cell. 67:1991;11-19.
39. Southern E.M. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98:1975;503-517.
40. Smith H.C., Sowden M.P. Base-modification mRNA editing through deamination - the good, the bad and the unregulated. Trends Genet. 12:1996;418-424.
41. Schneuwly S., Kuroiwa A., Baumgartner P., Gehring W.J. Structural organization and sequence of the homeotic gene Antennapedia of Drosophila melanogaster. EMBO J. 5:1986;733-739.
42. Yao K.-M., Samson M.-L., Reeves R., White K. Gene elav of Drosophila melanogaster: a prototype for neuronal-specific RNA-binding protein gene families that is conserved in flies and humans. J. Neurobiol. 24:1993;723-739.