Potentiation of iron-induced lipid peroxidation by a series of bipyridyls in relation to their ability to reduce iron

Toxicology Letters

Volumn 93, Issue 1, 1997, Pages 65-71

  Fernandez, Y ^a   Anglade, F ^a   Mitjavila, S ^a  

^a CEMAGREF   (France)

Author keywords

Bipyridyls; Iron; Lipid peroxidation; Microsomes

Indexed keywords

BENZYLVIOLOGEN; BIPYRIDINE DERIVATIVE; DIQUAT; IRON; PARAQUAT;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; LIPID PEROXIDATION; LIVER MICROSOME; MALE; NONHUMAN; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; RAT; REDUCTION;

ANIMALS; BENZYL VIOLOGEN; DIQUAT; DRUG SYNERGISM; HERBICIDES; IRON; LIPID PEROXIDATION; MALE; MICROSOMES, LIVER; NADP; OXIDATION-REDUCTION; OXYGEN; PARAQUAT; RATS; RATS, WISTAR;

ANIMALIA;

EID: 0031578444     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(97)00073-8     Document Type: Article

References (25)

1. Bus, J.S., Aust, S.D., Gibson, J.E., 1974. Superoxide and singlet oxygen catalyzed lipid peroxidation as possible mechanisms for paraquat toxicity. Biochem. Biophys. Res. Commun. 58, 749-755.
2. Darmon, N., Fernandez, Y., Periquet, A., Mitjavila, S., 1992. Superoxide anion scavenging capacity measured by a polarographic method, comparison with a colourimetric method. Free Rad. Res. Commun. 17, 97-107.
3. Fernandez, Y., Mitjavila, S., Anglade, F., Rodriguez, C., Mitjavila, M.T., 1995. Paraquat potentiates iron-induced microsomal lipid peroxidation: modulation by the diet lipid composition. Redox Rep. 1, 213-218.
4. Ghoshal, A.K., Recknagel, R.O., 1965. Positive evidence of acceleration of lipoperoxidation in rat liver by carbon tetrachloride: in vitro experiments. Life Sci. 4, 1521-1530.
5. Griffin-Green, E., Zalaska, M.M., Erecinska, M., 1988. Adriamycin-induced Lipid peroxidation in mitochondria and microsomes. Biochem Pharmacol. 37, 3071-3077.
6. Hall, A.H., 1995. Paraquat usage. In: Ch. Bismuth, A.H. Hall (Eds.), Paraquat Poisoning-Mechanisms, Prevention, Treatment. Drug and Chemical Toxicology. Marcel Dekker, New York, pp. 17-35.
7. Kenel, M.F., Bestervelt, L.L., Kulkarni, A.P., 1987. Human placental lipid peroxidation. II. NADPH and iron dependent stimulation of microsomal lipid peroxidation by paraquat. Gen. Pharmacol, 18, 373-378.
8. Kohen, R., Chevion, M., 1985. Paraquat toxicity is enhanced by iron and reduced by desferrioxamine in laboratory mice. Biochem. Pharmacol. 34, 1841-1843.
9. Lowrey, K., Glende, E.A., Recknagel, R.O., 1981. Destruction of liver microsomal calcium pump activity by carbon tetrachloride and bromotrichloromethane. Biochem. Pharmacol. 30, 135-140.
10. Lowry, O.H., Rosebrough, N.J., Farr, A.L., Randall, R.J., 1951. Protein measurement with the Folin phenol reagent. J. Biol. Chem. 193, 265-275.
11. Miller, D.M., Buettner, G.R., Aust, S.D., 1990. Transition metals as catalysts of 'autoxidation' reactions. Free Rad. Biol. Med. 8, 95-108.
12. Misra, H.P., Gorsky, L.D., 1981. Paraquat and NADPH-dependent lipid peroxidation in lung microsomes. J. Biol. Chem. 256, 994-998.
13. Odom, A.L., Hating, C.A., Stanley, J.S., Benson, A.M., 1992. Biochemical determinants of adriamycin toxicity in mouse liver, heart and intestine. Biochem, Pharmacol. 43, 831-836.
14. Samokyszyn, V.M., Thomas, C.E., Reif, D.W., Saito, M., Aust, S.D., 1988. Release of iron from ferritin and its role in oxygen radical toxicities. Drug Metab. Rev. 19, 283-303.
15. Sandy, M.S., Moldeus, P., Ross, D., Smith, M.T., 1986. Role of redox cycling and lipid peroxidation in bipyridyl herbicide cytotoxicity - studies with a compromised isolated hepatocyte model system. Biochem. Pharmacol. 35, 3095-3101.
16. Steffen, C., Netter, K.J., 1979. On the mechanisms of paraquat action on microsomal oxygen reduction and its relation to lipid peroxidation. Toxicol. Appl. Pharmacol. 47, 593-602.
17. Talcott, R.E., Shi, H., Wei, E.T., 1979. Dissociation of microsomal oxygen reduction and lipid peroxidation with the electron acceptors, paraquat and menadione. Biochem. Pharmacol. 28, 665-671.
18. Thomas, C.E., Aust, S.D., 1986. Reductive release of iron from ferritin by cation free radicals of paraquat and other bipyridyls. J. Biol. Chem. 265, 13064-13070.
19. Tomita, M., Okuyama, T., 1994. Effect of paraquat on the malondialdehyde level in rat liver microsomes (in vitro). Arch. Toxicol. 68, 187-192.
20. Trush, M.A., Mimnaugh, E.G., Ginsbung, E., Gram, T.E., 1982. Studies on the in vitro interaction of mitomycin c, nitrofurantoin and paraquat with pulmonary microsomes - stimulation of reactive oxygen-dependent lipid peroxidation. Biochem. Pharmacol. 5, 805-814.
21. Trush, M.A., Mimnaugh, E.G., Ginsburg, E., Gram, T.E., 1981. In vitro stimulation by paraquat of reactive oxygen mediated lipid peroxidation in rat lung microsomes. Toxicol. Appl. Pharmacol. 60, 279-286.
22. Ursini, F., Maiorino, M., Hochstein, P., Ernster, L., 1989. Microsomal lipid peroxidation mechanisms of initiation -the role of iron and iron chelators. Free Rad. Biol. Med. 6, 31-36.
23. Vile, G.F., Winterbourn, C.C., 1988a. Adriamycin-dependent peroxidation in rat liver and heart microsomes catalysed by iron chelates and ferritin - maximum peroxidation at low oxygen partial pressures. Biochem. Pharmacol. 37, 2893-2897.
24. 3+ chelates and ferritin. Enhancement by adriamycin, paraquat, menadione and anthraquinone-2-sulfonate and inhibition by oxygen. Arch. Biochem. Biophys. 267, 606-613.
25. Winterbourn, C.C., Vile, G.F., Monteiro, H.P., 1991. Ferritin, lipid peroxidation and redox-cycling xenobiotics. Free Rad. Res. Commun. 12, 107-114.