Design, synthesis and biological evaluation of 1,3-diaminopropanes: A new class of polyamine analogs as leishmanicidal agents

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 6, 1997, Pages 675-680

  Kumar, Versha Vinay ^a   Singh, Sudhir K ^a   Sharma, S ^a   Bhaduri, A P ^a   Gupta, Suman ^a   Zaidi, Alima ^a   Tiwari, Suman ^a   Katiyar, J C ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 PROPANEDIAMINE; ANTILEISHMANIAL AGENT; POLYAMINE DERIVATIVE; STIBOGLUCONATE SODIUM;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG ACTIVITY; DRUG DESIGN; DRUG SCREENING; DRUG SYNTHESIS; HAMSTER; INTRAPERITONEAL DRUG ADMINISTRATION; LEISHMANIA DONOVANI; LEISHMANIASIS; NONHUMAN; ORAL DRUG ADMINISTRATION;

EID: 0031576894     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)00087-5     Document Type: Article

References (10)

1. 1. CDRI, Communication No. 5611.
2. 2. Bachrach, U; Abu-Elheiga. Med. Biol. 1981, 59(5-6), 441.
3. 3. Schnur, L.F.; Bachrach, U. FEBS Lett. 1979, 106(1), 202.
4. 4. Baumann, R.J.; Hanson, L.W.; McCann, P.P.; Sjoerdsma, A.; Bitonti, J.A. Antimicrob Agents and Chemother, 1990, 34(5), 722.
5. 5. Baumann, R.J., McCann, P.P.; Bitonti, J.A. Antimicrob. Agents and Chemother, 1991, 35(7), 1403.
6. 6. Raufos, I.; Hay, S.; Schwarz, D.R. J. Med. Chem. 1996, 39, 1514.
7. 4: C, 68.91, H, 9.45, N, 21.30%).
8. 4O: C, 67.54, H, 8.60, N, 18.54%).
9. 9. Bhatnagar, S.; Guru, P.Y.; Katiyar, J.C.; Srivastava, R.; Mukherjee, A.; Akhtar, M.Z.; Seth, M.; Bhaduri, A.P. Ind. J. Med. Res., 1989, 89, 439.
10. 10. Kandpal, M.; Tekwani, B.L.; Chauhan, P.M.S.; Bhaduri, A.P. Life Sciences, 1996, 59(7), PL 75.