Tetraazaacenaphthene, tetraazaphenalene and 1,3,4-thiadiazole derivatives as potential leishmanicides

Bioorganic and Medicinal Chemistry Letters

Volumn 7, Issue 6, 1997, Pages 651-656

  Ram, V J ^a   Goel, A ^a   Kandpal, M ^a   Mittal, N ^a   Goyal, N ^a   Tekwani, B L ^a   Guru, P Y ^a   Rastogi, A K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

1,3,4 THIADIAZOLE DERIVATIVE; ANTILEISHMANIAL AGENT; STIBOGLUCONATE SODIUM;

AMASTIGOTE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG ACTIVITY; DRUG SCREENING; DRUG SYNTHESIS; HAMSTER; INTRAPERITONEAL DRUG ADMINISTRATION; LEISHMANIASIS; NONHUMAN;

EID: 0031576888     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-894X(97)00086-3     Document Type: Article

References (13)

1. 1. Ram, V.J.; J. Prakt. Chem., 1989, 331, 893.
2. 2. Ram, V.J.; Indian J. Chem., 1988, 270, 825.
3. 3. Ram, V.J.; Kapil, A.; Guru, P.Y.; Indian J. Chem., 1990, 29B, 1129.
4. 4. Steck, A.E.; Prog. Drug Res., 1974, 18, 290.
5. 5. Ram, V.J.; J. Prakt. Chem., 1989, 331, 957.
6. 6. Renoux, G.; Renoux, M.; J. Immunology, 1972, 109, 761.
7. 7. Chauhan, P.M.S.; Iyer, R.N.; Dutta, G.P.; Indian J. Chem., 1983, 228, 894.
8. 8. Gosh, B.K.; Ray, D.H.; Chatterjee, A.N.; J. Trop. Med. Hyg., 1989, 92, 383.
9. 9. Ram, V.J.; Haque, N.; Singh, S.K.; Nath, M. and Shoeb, A.; Phosphorus Sulfur and Silicon, 1994, 88, 155.
10. 10. Ram, V.J.; Nath, M.; Phosphorus Sulfur and Silicon, 1955, 105, 11.
11. 11. Grogl, M.A.; Oduola, A.M.J.; Cordero, L.D.C. and Kyle, D.E.; Exp. Parasitol., 1989, 69, 78.
12. 12. Bhatnagar, S.; Guru, P.Y.; Katiyar, J.C.; Srivastava, R.; Mukherjee, A.; Akhtar, M.J.; Bhaduri, A.P.; Indian J. Med. Res., 1989, 89, 439.
13. 13. Formula used for calculating percent inhibition = (An × 100)/(Ti × In) An = Actual number of parasites in treated animals Ti = Times increased of parasites in control In = Initial number of parasties in treated animals