The immune response to tetanus in elderly people: Shortened immunological memory affects the duration of protection;Die Immunreaktion gegenuber Tetanus im Alter: Wie lange halt der Impfschutz?

Wiener Klinische Wochenschrift

Volumn 109, Issue 19, 1997, Pages 767-770

  Steger, Maria Magdalena ^a   Maczek, Christian ^a   Berger, Peter ^a   Grubeck Loebenstein, Beatrix ^a  

^a ERICH SCHMID INSTITUTE OF MATERIALS SCIENCE   (Austria)

Author keywords

aging; antibodies; lymphocytes; tetanus; vaccination

Indexed keywords

TETANUS TOXOID; BACTERIUM ANTIBODY;

ADULT; AGED; AGING; ARTICLE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; IMMUNE RESPONSE; MALE; TETANUS; VACCINATION; BLOOD; CLOSTRIDIUM TETANI; IMMUNOLOGICAL MEMORY; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MONOCYTE; REFERENCE VALUE;

ADULT; AGED; AGING; ANTIBODIES, BACTERIAL; CLOSTRIDIUM TETANI; FEMALE; HUMANS; IMMUNE TOLERANCE; IMMUNOLOGIC MEMORY; LYMPHOCYTE ACTIVATION; MALE; MONOCYTES; REFERENCE VALUES; TETANUS TOXOID;

EID: 0031576204     PISSN: 00435325     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (20)

1. Aronson M (1993) Involution of the thymus revisited: immunological trade-offs as an adaption to aging. Mech Ageing Dev 72: 49-55
2. Ben-Yehuda A, Weksler ME (1992) Host resistance and the immune system. Clin Geriatr Med 8: 701-711
3. Berger P, Panmoung W, Khaschabi D, Mayregger B, Wick G (1988) Antigenic features of human follicle stimulating hormone delineated by monoclonal antibodies and construction of an immunoradiometric assay. Endocrinology 123: 2351-2359
4. George AJT, Ritter G (1996) Thymic involution with ageing: obsolence or good housekeeping? Immunol Today 17: 267-272
5. Gergen PJ, McQuillan GM, Kiely M, Ezzati-Rize TM, Sutter RW, Viralla G (1995) A population-based serologic survey of immunity to tetanus in the United States. N Engl J Med 32: 761-766
6. German A, Fattal-German M, Bizzini B (1987) Immunological protection against tetanus. Bull Acad Natl Med 171: 735-741
7. Giachino C, Granziero L, Modena V, Maiocco V, Lomater C, Fantini F, et al (1994) Clonal expansions of V delta 1 + and V delta 2+ cells increase with age and limit the repertoire of human g/d T cells. Eur J Immunol 24: 1914-1918
8. Globerson A (1995) T lymphocytes and aging. Int Arch Allergy Immunol 67: 491-497
9. + and specifically recognize autologous fibroblasts. J Clin Invest 93: 2738-2743
10. Hallen J (1963) Frequency of abnormal serum globulin (M-components) in the aged. Acta Mod Scand 173: 737-745
11. Hodes RJ (1995) Molecular alterations in the aging immune system. J Exp Med 182: 1-3
12. Hu A, Ehleiter D, Ben-Yehuda A, Schwab R, Russo C, Szabo P (1993) Effect of age on the expressed B cell repertoire: role of B cell subsets. Int Immunol 5: 1035-1039
13. Huber LA, Xu Q, Jürgens G, Bock G, Buhler E, Gey KF, et al (1991) Correlation of lymphocyte lipid composition membrane microviscosity and mitogen response in the aged. Eur J Immunology 21: 2761-2765
14. Lighthart GJ, Corberand JX, Fournier C, Galanaud P, Hijmans W, Kennes B, et al (1984) Admission criteria for immunogerontological studies in man: The Senieur protocol. Mech Ageing Dev 28: 47-55
15. Matzinger P (1994) Immunologhy: memories are made of this? Nature 369: 605-606
16. Pawelec G (1995) Immunosenescence: ageing of the immune system. Immunol Today 16: 420-422
17. Posnett DN, Sinha R, Kabak S, Russo C (1994) Clonal populations of T cells in normal elderly humans: the T cell equivalent to 'benign monoclonal gammapathy'. J Exp Med 179: 609-618
18. Reibnegger G, Huber LA, Jürgens G, Schönitzer D, Werner ER, Wachter H, Wick G (1988) Approach to define 'normal aging' in man: immune function, serum lipids, lipoproteins and neopterin levels. Mech Ageing Dev 46: 67-82
19. Sprent J, Tough DF (1994) Lymphocyte life span and memory. Science 265: 1395-1400
20. Trmal J, Jilek D (1986) Antibody response to tetanus in people in older age groups. Cesk Epidemiol Mikrobiol Imunol 35: 232-238