On the regiochemistry of cyclialkylation of regiodefined 4-halo-1-alkenylmetals producing cyclobutenes

Tetrahedron Letters

Volumn 38, Issue 7, 1997, Pages 1149-1152

  Liu, Fang ^a   Negishi, Ei ichi ^a  

^a PURDUE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOBUTANE DERIVATIVE; CYCLOBUTENE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CYCLIZATION; DRUG SYNTHESIS; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0031575599     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00011-7     Document Type: Article

References (9)

1. 1. Negishi, E.; Boardman, L. D.; Tour, J. M.; Sawada, H.; Rand, C. L. J. Am. Chem. Soc. 1983, 105, 6344.
2. 2. Boardman, L. D.; Bagheri, V.; Sawada, H.; Negishi, E. J. Am. Chem. Soc. 1984, 106, 6105.
3. 3. Negishi, E.; Boardman, L. D.; Sawada, H.; Bagheri, V.; Stoll, A. T.; Tour, J. M.; Rand, C. L. J. Am. Chem. Soc. 1988, 110, 5383.
4. 4. Negishi, E.; Holmes, S. J.; Tour, J. M.; Miller, J, A.; Cederbaum, F. E.; Swanson, D. R.; Takahashi, T. J. Am. Chem. Soc. 1989, 111, 3336.
5. 5. Gibbs, R. A.; Okamura, W. H. J. Am. Chem. Soc. 1988, 110, 4062.
6. 6. Negishi, E.; Liu, F.; Choueiry, D.; Mohamud, M. M.; Silveira, A., Jr.; Reeves, M. J. Org. Chem. 1996, 61, 8325.
7. 7. For references on other syntheses of cyclobutenes, see Ref. 6.
8. 8. Negishi, E.; Ma, S. J. Org. Chem. 1997, 62, 0000.
9. 9. Günther, H. "NMR Spectroscopy," 2nd Ed., John Wiley & Sons, New York, 1992, p. 477.