Mechanism and stereoselectivity of indirect Wittig reaction via isolation of 1,2-hydroxyphosphonium salt

Tetrahedron Letters

Volumn 38, Issue 7, 1997, Pages 1215-1218

  Nishizawa, Mugio ^a   Komatsu, Yasuko ^a   García, Dulce M ^a   Noguchi, Yohko ^a   Imagawa, Hiroshi ^a   Yamada, Hidetoshi ^a  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ALDEHYDE; ALKENE;

ARTICLE; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; METHODOLOGY; REACTION ANALYSIS; STEREOCHEMISTRY;

EID: 0031575576     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00020-8     Document Type: Article

References (18)

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11. 11. Maryanoff, B. E.; Reitz, A. B.; Mutter, M. S.; Inners, R. R.; Almond, Jr. H. R.; Whittle, R. R.; Olofson, R. A. J. Am. Chem. Soc. 1986, 108, 7664.
12. 12. Volatron, F.; Eisenstein, O. J. Am. Chem. Soc. 1987, 109, 1.
13. 13. Nishizawa, M.; Garcia, D. M.; Minagawa, R.; Noguchi, Y.; Imagawa, H.; Yamada, H.; Watanabe, R.; Yoo, Y. C.; Azuma, I. Synlett, 1996, 452.
14. 13C NMR, IR, and FAB MS spectrum.
15. 15. Stereochemical assignments of 7a and 7b are difficult from nmr spectra of the mixture of 7ab.
16. 16. Gray, G. A.; Cremer, S. E.; Marsi, K. L. J. Am. Chem. Soc. 1976, 98, 2109.
17. 17. Salts 7ab are insoluble in toluene.
18. -3, and final R value was 0.045 for 2249 reflections.