Mouse mammary tumor virus superantigens require N-linked glycosylation for effective presentation to T cells

Virology

Volumn 228, Issue 2, 1997, Pages 161-170

  McMahon, Christopher W ^a   Bogatzki, Lisa Y ^a   Pullen, Ann M ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

SUPERANTIGEN;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CONTROLLED STUDY; GLYCOSYLATION; IMMUNOBLOTTING; MOUSE; MOUSE MAMMARY TUMOR ONCOVIRUS; NONHUMAN; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; VIRUS TRANSMISSION;

ANIMALIA; MAMMARY TUMOR ONCOVIRUS; MAMMARY TUMOR VIRUS; MOUSE MAMMARY TUMOR VIRUS; ONCOVIRINAE; TUMOR VIRUS;

EID: 0031575516     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1996.8388     Document Type: Article

References (57)

1. Acha-Orbea A., Held W., Waanders G., Shakhov A., Scarpellino L., Lees R., MacDonald H. Exogenous and endogenous mouse mammary tumor virus superantigens. Immunol. Rev. 131:1993;5.
2. Acha-Orbea H., MacDonald H. R. Superantigens of mouse mammary tumor virus. Annu. Rev. Immunol. 13:1995;459-486.
3. Bazin A., Darveau A., Martel F., Pelletier A., Piche L., St.Laurent M., Thibault L., Demers A., Boyer L., Lemieux G., Lemieux R. Increased avidity of mutant IgM antibodies caused by the absence of COOH-terminal glycosylation of the μ H chain. J. Immunol. 149:1992;3889-3893.
4. Beutner U., Frankel W. N., Cote M., Coffin J., Huber B. Mls-1 is encoded by the long terminal repeat open reading frame of the mouse mammary tumor provirusMtv-7. Proc. Natl. Acad. Sci. USA. 89:1992;5432-5436.
5. Brandt-Carlson C., Butel J., Wheeler D. Phylogenetic and structural analyses of MMTV LTR ORF sequences of exogenous and endogenous origins. Virology. 193:1993;171-185.
6. Brandt-Carlson C., Butel J. Detection and characterization of a glycoprotein encoded by the mouse mammary tumor virus long terminal repeat gene. J. Virol. 65:1991;6051-6060.
7. Cazenave P. A., Marche P., Jouvin-Marche E., Voegtle D., Bonhomme F., Bandeira A., Coutinho A. Vβ17-gene polymorphism in wild-derived mouse strains: Two amino acid substitutions in the Vβ17 region alter drastically T cell receptor specificity. Cell. 63:1990;717-728.
8. Chervonsky A., Xu J., Barlow A., Kherry M., Flavell R., Janeway C. Direct physical interaction involving CD40 ligand on T cells and CD40 on B cells is required to propogate MMTV. Immunity. 3:1995;139-146.
9. Choi Y., Kappler J., Marrack P. A superantigen encoded in the open reading frame of the 3′ long terminal repeat of mouse mammary tumour virus. Nature. 350:1991;203-207.
10. Choi Y., Marrack P., Kappler J. Structural analysis of a mouse mammary tumor virus superantigen. J. Exp. Med. 175:1992;847-852.
11. Dellabona P., Peccoud J., Kappler J., Marrack P., Benoist C., Mathis D. Superantigens interact with MHC class II molecules outside of the antigen groove. Cell. 62:1990;1115-1121.
12. Dickson C., Eisenmann R., Fan H., Hunter E., Teich N., Varmus H. Protein biosynthesis and assembly. RNA Tumor Virus. 1982;Cold Spring Harbor Laboratory Press, Cold Spring Harbor. p. 513-648.
13. Dyson P. J., Knight A. M., Fairchild S., Simpson E., Tomonari K. Genes encoding ligands for detection of Vβ11 T cells cosegregate with mammary tumour virus genomes. Nature. 349:1991;531-532.
14. Frankel W. N., Rudy C., Coffin J. M., Huber B. T. Linkage of Mls genes to endogenous mouse mammary tumour viruses of inbred mice. Nature. 349:1991;526-528.
15. Golovkina T., Chervonsky A., Dudley J., Ross J. Transgenic mouse mammary tumor virus superantigen expression prevents viral infection. Cell. 69:1992;637-645.
16. Gunning P., Leavitt J., Muscat G., Ng S., Kedes L. A human b-actin expression vector system directs high-level accumulation of antisense transcripts. Proc. Natl. Acad. Sci. USA. 84:1987;4831-4835.
17. Harding C. V., Unanue E. Quantitation of antigen-presenting cell MHC class II/peptide complexes necessary for T-cell stimulation. Nature. 346:1990;574-576.
18. +. Immunol. Rev. 93:1986;35-51.
19. +. J. Exp. Med. 177:1993a;359-366.
20. Held W., Waanders G., Shakhov A., Scarpellino L., Acha-Orbea A., MacDonald H. R. Superantigen-induced immune stimulation amplifies mouse mammary tumor virus infection and allows virus transmission. Cell. 74:1993b;529-540.
21. Held W., Waanders G., Acha-Orbea H., MacDonald H. R. Reverse transcriptase-dependent and -independent phases of infection with mouse mammary tumor virus: Implications for superantigen function. J. Exp. Med. 180:1994;2347-2351.
22. Herman A., Kappler J., Marrack P., Pullen A. M. Superantigens: mechanism of T-cell stimulation and role in immune responses. Annu. Rev. Immunol. 9:1991;745-772.
23. Ho S., Hunt H., Horton R., Pullen J., Pease L. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene. 77:1989;51-59.
24. Hoe M., Hunt R. Loss of one asparagine-linked oligosaccharide from human transferrin receptors results in specific cleavage and association with the endoplasmic reticulum. J. Biol. Chem. 267:1992;4916-4923.
25. Kappler J., Skidmore B., White J., Marrack P. Antigen-inducible, H-2-restricted, interleukin-2 producing T cell hybridomas. Lack of independent antigen and H-2 recognition. J. Exp. Med. 153:1981;1198-1214.
26. Karapetian O., Shakhov A., Kraehenbuhl J. P., Acha-Orbea H. Retroviral infection of neonatal peyer's patch lymphocytes: The mouse mammary tumor virus model. J. Exp. Med. 180:1994;1511-1516.
27. Knight A. M., Harrison G. B., Pease R. J., Robinson P. J., Dyson P. J. Biochemical analysis of the mouse mammary tumor virus long terminal repeat product. Evidence for the molecular structure of an endogenous superantigen. Eur. J. Immunol. 22:1992;879-882.
28. Koch N., Koch S., Hammerling G. Ia invariant chain detected on lymphocyte surfaces by monoclonal antibody. Nature. 299:1982;644-645.
29. Korman A., Bourgarel P., Meo T., Rieckhof G. The mouse mammary tumour virus long terminal repeat encodes a type II transmembrane glycoprotein. EMBO J. 11:1992;1901-1905.
30. Kozak C., Peters G., Pauley R., Morris V., Michalides R., Dudley J., Greene M., Davisson M., Prakash O., Vaidya A., Hilgers J., Verstraten A., Hynes N., Diggelmann H., Peterson D., Cohen J. C., Dickson C., Sarkar N., Nusse R., Varmus H., Callahan R. A standardized nomenclature for endogenous mouse mammary tumor viruses. J. Virol. 61:1987;1651-1654.
31. Krummenacher C., Diggelmann H. The mouse mammary tumor virus long terminal repeat encodes a 47 kDa glycoprotein with a short half-life in mamnmalian cells. Mol. Immunol. 30:1993;1151-1157.
32. Lukacher A., Ma Y., Carroll J., Abromson-Leeman S., Laning J., Dorf M. E., Benjamin T. Susceptibility to tumors induced by polyoma virus is conferred by an endogenous mouse mammary tumor virus superantigen. J. Exp. Med. 181:1995;1683-1692.
33. Morishima C., Norby-Slycord C., McConnell K., Finch R., Nelson A., Farr A., Pullen A. M. Expression of two structurally identical viral superantigens results in thymic elimination at distinct developmental stages. J. Immunol. 153:1994;5091-5103.
34. Mottershead D., Hse P., Urban R., Strominger J., Huber B. T. Direct binding of theMtv. Immunity. 2:1995;149-154.
35. Olivares L., Aragon C., Gimenez C., Zafra F. The role ofN. J. Biol. Chem. 270:1995;9437-9442.
36. Olson T., Lane M. Post-translational acquisition of insulin binding activity by the insulin proreceptor. Correlation to recognition by autoimmune antibody. J. Biol. Chem. 262:1987;6816-6822.
37. Park C., Jung M., Choi Y., Winslow G. Proteolytic processing is required for viral superantigen activity. J. Exp. Med. 181:1995;1899-1904.
38. Pullen A. M., Marrack P., Kappler J. W. The T cell repertoire is heavily influenced by tolerance to polymorphic self antigens. Nature. 335:1988;796-801.
39. Pullen A. M., Potts W., Wakeland E. K., Kappler J., Marrack P. Surprisingly uneven distribution of the T cell receptor Vβ repertoire in wild mice. J. Exp. Med. 171:1990a;49-62.
40. a. Cell. 61:1990b;1365-1374.
41. Pullen A. M., Bill J., Kubo R. T., Marrack P., Kappler J. W. Analysis of the interaction site for the self superantigen Mls-1(a) on T-cell receptor Vβ J. Exp. Med. 173:1991;1183-1192.
42. Pullen A. M., Choi Y., Kushnir E., Kappler J., Marrack P. The open reading frames in the 3′ long terminal repeats of several mouse mammary tumor virus integrants encode Vβ3-specific superantigens. J. Exp. Med. 175:1992;41-47.
43. Rechsteiner M. PEST sequences are signals for rapid intracellular proteolysis. Semin. Cell. Biol. 1:1990;433-440.
44. Reiner S., Zheng S., Corry D., Locksley R. Constructing polycompetitor cDNAs for quantitative PCR. J. Immunol. Methods. 165:1993;37-46.
45. Rogers S., Wells R., Rechsteiner M. Amino acid sequences common to rapidly degraded proteins: The PEST hypothesis. Science. 234:1986;364-369.
46. Slieker L. J., Martensen T. M., Lane M. D. Synthesis of epidermal growth factor receptor in human A431 cells. Glycosylation-dependent acquisition of ligand binding activity occurs post-translationally in the endoplasmic reticulum. J. Biol. Chem. 261:1986;15233-15241.
47. Stellwagen R. Involvement of sequences near both amino and carboxyl termini in the rapid intracellular degradation of tyrosine aminotransferase. J. Biol. Chem. 267:1992;23713-23721.
48. Ullrich A., Bell J. R., Chen E. Y., Herrera R., Petruzzelli L. M., Dull T. J., Gray A., Coussens L., Lioa Y., Tsubokawa M., Mason A., Seeburg P., Grunfeld C., Rosen O., Ramachandran J. Human insulin receptor and its relationship to the tyrosine kinases family of oncogenes. Nature. 313:1985;756-761.
49. Unkeless J. Characterization of a monoclonal antibody directed against mouse marcophage and lymphocyte Fc receptors. J. Exp. Med. 150:1979;580-596.
50. Ware F. E., Vassilakos A., Peterson P. A., Jackson M. R., Lehrman M. A., Williams D. B. The molecular chaperone calnexin binds Glc1Man9GlcNAc2 oligosaccharide as an initial step in recognizing unfolded glycoproteins. J. Biol. Chem. 270:1995;4697-4704.
51. West C. M. Current ideas on the significance of protein glycosylation. Mol. Cell. Biochem. 72:1986;3-20.
52. White J., Pullen A. M., Choi K., Marrack P., Kappler J. Antigen recognition properties of mutant Vβ3+ T cell receptors are consistent with an immunoglobulin-like structure for the receptor. J. Exp. Med. 177:1993;119-125.
53. Williams A., Enns C. A region of the C-terminal portion of the human transferrin receptor contains an asparagine-linked glycosylation site critical for receptor structure and function. J. Biol. Chem. 268:1993;12780-12786.
54. Winslow G., Scherer M., Kappler J., Marrack P. Detection and biochemical characterization of the mouse mammary tumor virus 7 superantigen (Mls-1a). Cell. 71:1992;719-730.
55. Winslow G., Marrack P., Kappler J. Processing and major histocompatibility complex binding of the MTV7 superantigen. Immunity. 1:1994;23-33.
56. Yagi J., Baron J., Buxser S., Janeway C. A. Bacterial proteins that mediate the association of a defined subset of T cell receptor: CD4 complexes with class II MHC. J. Immunol. 144:1990;892-901.
57. Yazdanbaksh K., Park C., Winslow G. M., Choi Y. Direct evidence for the role of COOH terminus of mouse mammary tumor virus superantigen in determining T cell receptor Vβ specificity. J. Exp. Med. 178:1993;737-741.