Molecular analysis and characterization of a protein involved in the replication of intracellular Toxoplasma gondii

Molecular and Biochemical Parasitology

Volumn 90, Issue 2, 1997, Pages 403-413

  Matsuura, Tadashi ^a   Kasper, Lloyd H ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

Molecular analysis; Replication; Toxoplasma gondii

Indexed keywords

COMPLEMENTARY DNA; CYTOPLASM PROTEIN; DETERGENT; MEMBRANE ANTIGEN; MONOCLONAL ANTIBODY; MONOMER; POLYCLONAL ANTIBODY; PROTEIN ANTIBODY;

AMINO ACID SEQUENCE; APICOMPLEXA; ARTICLE; BIOTINYLATION; CELL DIVISION; CONTROLLED STUDY; DENSITY GRADIENT CENTRIFUGATION; GEL FILTRATION; GENE EXPRESSION; GENE SEQUENCE; IMMUNOBLOTTING; MOLECULAR BIOLOGY; MOLECULAR CLONING; NEOSPORA CANINUM; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; SARCOCYSTIS; SOUTHERN BLOTTING; TOXOPLASMA GONDII;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; APICOMPLEXA; BASE SEQUENCE; BIOTINYLATION; BLOTTING, SOUTHERN; CYTOPLASM; DNA, PROTOZOAN; HOST-PARASITE RELATIONS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; PROTOZOAN PROTEINS; SEQUENCE ANALYSIS, DNA; SOLUBILITY; TOXOPLASMA;

APICOMPLEXA; BESNOITIA JELLISONI; NEOSPORA CANINUM; PROTOZOA; SARCOCYSTIDAE; SARCOCYSTIS; TOXOPLASMA GONDII;

EID: 0031574461     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(97)00174-6     Document Type: Article

References (28)

1. Kasper L, Boothroyd J. Toxoplasma and toxoplasmosis. In: Warren K, editor. Immunology and Molecular Biology in Parasitic Infection. Blackwell Scientific, Boston, 1993:269-301.
2. Schwartzman J., Pfefferkorn E. Toxoplasma gondii: Purine synthesis and salvage in mutant host cells and parasites. Exp Parsitol. 53:1982;77-86.
3. Jones T.C. Multiplication of Toxoplasma gondii in enucleate fibroblast. Proc Soc Exp Biol Med. 142:1973;1256-1271.
4. Beckers C.J. The Toxoplasma gondii rhoptry protein ROP 2 is inserted into the parasitophorous vacuole membrane, surrounding the intracellular parasite, and is exposed to the host cell cytoplasm. J Cell Biol. 127(4):1994;947-961.
5. Ossorio P.N., Dubremetz J.F., Joiner K.A. A soluble secretory protein of the intracellular parasite Toxoplasma gondii associates with the parasitophorous vacuole membrane through hydrophobic interactions. J Biol Chem. 269(21):1994;15350-15357.
6. Cesbron-Delauw M.F. Molecular characterization of a 23-kilodalton major antigen secreted by Toxoplasma gondii. Proc Natl Acad Sci USA. 86(19):1989;7537-7541.
7. Cesborn-Delauw M.F. Dense-granule organelles of Toxoplasma gondii: Their role in the host-parasite relationship. Parasitol Today. 10:1994;293-296.
8. Mercier C. Molecular characterization of a dense granule antigen (Gra 2) associated with the network of the parasitophorous vacuole in Toxoplasma gondii. Mol Biochem Parasitol. 58(1):1993;71-82.
9. Bermudes D. Cloning of a cDNA encoding the dense granule protein GRA3 from Toxoplasma gondii. Mol Biochem Parasitol. 68(2):1994;247-257.
10. Mevelec M.N. Molecular cloning of GRA4, a Toxoplasma gondii dense granule protein, recognized by mucosal IgA antibodies. Mol Biochem Parasitol. 56(2):1992;227-238.
11. Lecordier L. Molecular structure of a Toxoplasma gondii dense granule antigen (GRA 5) associated with the parasitophorous vacuole membrane. Mol Biochem Parasitol. 59(1):1993;143-153.
12. Lecordier L. Characterization of a dense granule antigen of Toxoplasma gondii (GRA6) associated to the network of the parasitophorous vacuole. Mol Biochem Parasitol. 70(1-2):1995;85-94.
13. Mineo J., Khan I., Kasper L. Toxoplasma gondii: A monoclonal antibody that inhibits intracellular replication. Exp Parasitol. 79:1994;351-361.
14. Kasper L.H., Crabb J.H., Pfefferkorn E.R. Purification of a major membrane protein of Toxoplasma gondii by immunoabsorption with a monoclonal antibody. J Immunol. 130:1983;2407-2412.
15. Alonso G., Guevara P., Ramirez J. Trypanosomatidae codon usage and GC distribution. Mem Inst Oswaldo Cruz. 87(4):1992;517-523.
16. Pollack Y. The genome of Plasmodium falciparum I: DNA base composition. Nucleic Acids Res. 10(2):1982;539-546.
17. Chance M.L. DNA base composition differences between species of Leishmania. Trans R Soc Trop Med Hyg. 66(2):1972;352.
18. Neimark H., Blaker R.G. DNA base composition of Toxoplasma gondi grown in vivo. Nature. 216(115):1967;600.
19. Nagel S., Boothroyd J. The major surface antigen, P30, of Toxoplasma gondii is anchored by a glycolipid. J Biol Chem. 264:1989;5569-5574.
20. Nakai K., Kanehisa M. A knowledge base for predicting protein localization sites in eukaryotic cells. Genomics. 14:1992;897-911.
21. Subramani S. Targeting of proteins into the peroxisomal matrix. J Membrane Biol. 125:1992;99-106.
22. von Heijine G. A new method for predicting signal sequence cleavage sites. Nucleic Acids Res. 14:1986;4683-4690.
23. Altschul S. Basic local alignment search tool. J Mol Biol. 215:1990;403-410.
24. Prince J.B. Cloning, expression, and cDNA sequence of surface antigen P22 from Toxoplasma gondii. Mol Biochem Parasitol. 43(1):1990;97-106.
25. Burg J.L. Molecular analysis of the gene encoding the major surface antigen of Toxoplasma gondii. J Immunol. 141(10):1988;3584-3591.
26. Asai T. Biochemical and molecular characterization of nucleoside triphosphate hydrolase isozymes from the parasitic protozoan Toxoplasma gondii. J Biol Chem. 270(19):1995;11391-11397.
27. Ossorio P.N., Schwartzman J.D., Boothroyd J.C. A Toxoplasma gondii rhoptry protein associated with host cell penetration has unusual charge asymmetry. Mol Biochem Parasitol. 50(1):1992;1-15.
28. Needleman S.B., Wunsch C.D. A general method applicable to the search for similarities in the amino acid sequence of two proteins. J Mol Biol. 48:1970;443-453.