Abnormal limb regeneration in the short-toes mutant of the axolotl, Ambystoma mexicanum: Studies of age, level of amputation, and extracellular matrix

Journal of Experimental Zoology

Volumn 279, Issue 6, 1997, Pages 571-578

  Gassner, Kathleen M ^a   Tassava, Roya ^a  

^a OHIO STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; MONOCLONAL ANTIBODY;

AGING; AMBYSTOMA MEXICANUM; AMPUTATION; AMPUTATION STUMP; ANIMAL; ARTICLE; EXTRACELLULAR MATRIX; FLUORESCENT ANTIBODY TECHNIQUE; FORELIMB; GENE EXPRESSION REGULATION; HINDLIMB; HISTOLOGY; IMMUNOLOGY; METABOLISM; METHODOLOGY; PHYSIOLOGY; REGENERATION;

AGING; AMBYSTOMA MEXICANUM; AMPUTATION; AMPUTATION STUMPS; ANIMALS; ANTIBODIES, MONOCLONAL; COLLAGEN; EXTRACELLULAR MATRIX; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; FORELIMB; GENE EXPRESSION REGULATION; HINDLIMB; REGENERATION;

AMBYSTOMA MEXICANUM; ANIMALIA;

EID: 0031574224     PISSN: 0022104X     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-010X(19971215)279:6<571::AID-JEZ5>3.0.CO;2-K     Document Type: Article

References (12)

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2. Del Rio-Tsonis, K., C.H. Washabaugh, and P.A. Tsonis (1992) The mutant axolotl short toes exhibits impaired limb regeneration and abnormal basement membrane formation. Proc. Natl. Acad. Sci., U.S.A. 89:5502-5506.
3. Humphrey, R.R. (1967) Genetic and experimental studies on a lethal trait ("short toes") in the Mexican axolotl (Ambystoma mexicanum). J. Exp. Zool., 164:281-296.
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5. Klatt, K.P., E.V. Yang, and R.A. Tassava (1992) Monoclonal antibody MT2 identifies an extracellular matrix glycoprotein that is co-localized with tenascin during adult newt limb regeneration. Differentiation, 50:133-140.
6. Mescher, A.L. (1993) Development and regeneration of limbs in the short toes axolotl mutant. In: Limb Development and Regeneration. J.F. Fallon, P.F. Goetinck, R.O. Kelley, and D.L. Stocum, eds. Wiley-Liss, New York, pp. 181-191.
7. Tassava, R.A., B. Johnson-Wint, and J. Gross (1986) Regenerate epithelium and skin glands of the adult newt react to the same monoclonal antibody. J. Exp. Zool., 239:229-240.
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9. Tsonis, P.A. (1996) Limb Regeneration. Cambridge University Press, New York.
10. Washabaugh, C.H., K. Del Rio-Tsonis, and P.A. Tsonis (1993) Variable manifestations in the short toes (s) mutation of the axolotl. J. Morphol., 218:107-114.
11. Wei, Y., E.V. Yang, K.P. Klatt, and R.A. Tassava (1995) Monoclonal antibody MT2 identifies the urodele al chain of type XII collagen, a developmentally regulated extracellular matrix protein in regenerating newt limbs. Dev. Biol., 168:503-513.
12. Yang, E.V., D.T. Shima, and R.A. Tassava (1992) Monoclonal antibody ST1 identifies an antigen that is abundant in the axolotl and newt limb stump but is absent from the undifferentiated regenerate. J. Exp. Zool., 264:337-350.