t(5;7)(q34;q21) in acute megakaryoblastic leukemia associated with down syndrome

Cancer Genetics and Cytogenetics

Volumn 96, Issue 2, 1997, Pages 177-

  Ma, S K ^a   Ha, S Y ^a   Wan, T S K ^a   Chan, L C ^a  

^a QUEEN MARY HOSPITAL   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE DISEASE; ACUTE NONLYMPHOCYTIC LEUKEMIA; CASE REPORT; CHROMOSOME 5; CHROMOSOME 7; CHROMOSOME ABERRATION; CHROMOSOME BANDING PATTERN; CHROMOSOME DISORDER; DOWN SYNDROME; GENE TRANSLOCATION; GENETICS; HUMAN; LETTER; MALE; PRESCHOOL CHILD;

ACUTE DISEASE; CHILD, PRESCHOOL; CHROMOSOME ABERRATIONS; CHROMOSOME BANDING; CHROMOSOME DISORDERS; CHROMOSOMES, HUMAN, PAIR 5; CHROMOSOMES, HUMAN, PAIR 7; DOWN SYNDROME; HUMANS; LEUKEMIA, MEGAKARYOCYTIC, ACUTE; MALE; TRANSLOCATION, GENETIC;

EID: 0031570829     PISSN: 01654608     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (5)

1. Avet-Loiseau H, Mechinaud F, Harousseau JL (1995): Clonal Hematologic Disorders in Down Syndrome - a review. J Pediatr Hematol Oncol 17:19-24.
2. Kojima S, Matsuyama T, Sata T, Horibe K, Konishi S, Tsuchida M, Hayashi Y, Kigasawa Y, Okamura J, Nakahata T, Bessho F, Eguchi M, Nakazawa S, Ueda R (1990): Down's syndrome and acute leukemia in children: an analysis of phenotype by use of monoclonal antibodies and electron microscopic platelet peroxidase reaction. Blood 76:2348-2353.
3. Hayashi Y, Eguchi M, Sugita K, Nakazawa S, Sata T, Kojima S, Bessho F, Konishi S, Inaba T, Hanada R, Yamamoto K (1988): Cytogenetic findings and clinical features in acute leukemia and transient myeloproliferative disorder in Down's syndrome. Blood 72:15-23.
4. Kobayashi H, Espinosa R III, Fernald AA, Begy C, Diaz MO, Le Beau MM, Rowley JD (1993): Analysis of deletions of the long arm of chromosome 11 in hematologic malignancies with fluorescence in situ hybridization. Genes Chromosom Cancer 8:246-252.
5. Testoni N, Zaccaria A, Celso B, Tura S (1991): Unfavorable outcome of a patient with M2 acute non lymphocytic leukemia and a 47,XY,t(5;7)(q34:q21),+8 karyotype. Haematologica 76:65-68.