-
1
-
-
0025278341
-
Immunobiology and pathogenesis of hepatocellular injury in hepatitis B virus transgenic mice
-
Moriyama, T., S. Guilhot, K. Klopchin, B. Moss, C. A. Pinkert, R. D. Palmiter, R. L. Brinster, O. Kanagawa, and F. V. Chisari. 1990. Immunobiology and pathogenesis of hepatocellular injury in hepatitis B virus transgenic mice. Science 248:361.
-
(1990)
Science
, vol.248
, pp. 361
-
-
Moriyama, T.1
Guilhot, S.2
Klopchin, K.3
Moss, B.4
Pinkert, C.A.5
Palmiter, R.D.6
Brinster, R.L.7
Kanagawa, O.8
Chisari, F.V.9
-
2
-
-
0027453541
-
Mechanisms of class I restricted immunopathology: A transgenic mouse model of fulminant hepatitis
-
Ando, K., T. Moriyama, L. G. Guidotti, S. Wirth, R. D. Schreiber, H. J. Schlicht, S. Huang, and F. V. Chisari. 1993. Mechanisms of class I restricted immunopathology: a transgenic mouse model of fulminant hepatitis. J. Exp. Med. 178:1541.
-
(1993)
J. Exp. Med.
, vol.178
, pp. 1541
-
-
Ando, K.1
Moriyama, T.2
Guidotti, L.G.3
Wirth, S.4
Schreiber, R.D.5
Schlicht, H.J.6
Huang, S.7
Chisari, F.V.8
-
3
-
-
0028274539
-
Class I restricted cytotoxic T lymphocytes are directly cytopathic for their target cells in vivo
-
Ando, K., L. G. Guidotti, S. Wirth, T. Ishikawa, G. Missale, T. Moriyama, R. D. Schreiber, H. J. Schlicht, S. Huang, and F. V. Chisari. 1994. Class I restricted cytotoxic T lymphocytes are directly cytopathic for their target cells in vivo. J. Immunol. 152:3245.
-
(1994)
J. Immunol.
, vol.152
, pp. 3245
-
-
Ando, K.1
Guidotti, L.G.2
Wirth, S.3
Ishikawa, T.4
Missale, G.5
Moriyama, T.6
Schreiber, R.D.7
Schlicht, H.J.8
Huang, S.9
Chisari, F.V.10
-
4
-
-
0028348561
-
Cytotoxic T lymphocytes inhibit hepatitis B virus gene expression by a noncytolytic mechanism in transgenic mice
-
Guidotti, L. G., K. Ando, M. V. Hobbs, T. Ishikawa, R. D. Runkel, R. D. Schreiber, and F. V. Chisari. 1994. Cytotoxic T lymphocytes inhibit hepatitis B virus gene expression by a noncytolytic mechanism in transgenic mice. Proc. Natl. Acad. Sci. USA 91:3764.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 3764
-
-
Guidotti, L.G.1
Ando, K.2
Hobbs, M.V.3
Ishikawa, T.4
Runkel, R.D.5
Schreiber, R.D.6
Chisari, F.V.7
-
5
-
-
0030021968
-
Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes
-
Guidotti, L. G., T. Ishikawa, M. V. Hobbs, B. Matzke, R. Schreiber, and F. V. Chisari. 1996. Intracellular inactivation of the hepatitis B virus by cytotoxic T lymphocytes. Immunity 4:25.
-
(1996)
Immunity
, vol.4
, pp. 25
-
-
Guidotti, L.G.1
Ishikawa, T.2
Hobbs, M.V.3
Matzke, B.4
Schreiber, R.5
Chisari, F.V.6
-
6
-
-
0026664633
-
Hepatitis B surface antigen retention sensitizes the hepatocyte to injury by physiologic concentrations of gamma interferon
-
Gilles, P. N., D. L. Guerrette, R. J. Ulevitch, R. D. Schreiber, and F. V. Chisari. 1992. Hepatitis B surface antigen retention sensitizes the hepatocyte to injury by physiologic concentrations of gamma interferon. Hepatology 16:655.
-
(1992)
Hepatology
, vol.16
, pp. 655
-
-
Gilles, P.N.1
Guerrette, D.L.2
Ulevitch, R.J.3
Schreiber, R.D.4
Chisari, F.V.5
-
7
-
-
0024589094
-
Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice
-
Tiegs, G., M. Wolter, and A. Wendel. 1989. Tumor necrosis factor is a terminal mediator in galactosamine/endotoxin-induced hepatitis in mice. Biochem. Pharmacol. 38:627.
-
(1989)
Biochem. Pharmacol.
, vol.38
, pp. 627
-
-
Tiegs, G.1
Wolter, M.2
Wendel, A.3
-
8
-
-
0027998359
-
Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-α requires transcriptional arrest
-
Leist, M., F. Gantner, I. Bohlinger, P. G. Germann, G. Tiegs, and A. Wendel. 1994. Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-α requires transcriptional arrest. J. Immunol. 153:1778.
-
(1994)
J. Immunol.
, vol.153
, pp. 1778
-
-
Leist, M.1
Gantner, F.2
Bohlinger, I.3
Germann, P.G.4
Tiegs, G.5
Wendel, A.6
-
9
-
-
0029048073
-
Tumor necrosis factor-induced hepatic DNA fragmentation as an early marker of T celi-dependent liver injury in mice
-
Gantner, F., M. Leist, S. Jilg, P. G. Germann, M. A. Freudenberg, and G. Tiegs. 1995. Tumor necrosis factor-induced hepatic DNA fragmentation as an early marker of T celi-dependent liver injury in mice. Gastroenterology 109:166.
-
(1995)
Gastroenterology
, vol.109
, pp. 166
-
-
Gantner, F.1
Leist, M.2
Jilg, S.3
Germann, P.G.4
Freudenberg, M.A.5
Tiegs, G.6
-
10
-
-
0026643743
-
A T cell-dependent experimental liver injury in mice inducible by concanavalin A
-
Tiegs, G., J. Hentschel, and A. Wendel. 1992. A T cell-dependent experimental liver injury in mice inducible by concanavalin A. J. Clin. Invest. 90:196.
-
(1992)
J. Clin. Invest.
, vol.90
, pp. 196
-
-
Tiegs, G.1
Hentschel, J.2
Wendel, A.3
-
11
-
-
0028300351
-
T cell activation-associated hepatic injury: Mediation by tumor necrosis factors and protection by interleukin 6
-
Mizuhara, H., E. O'Neill, N. Seki, T. Ogawa, C. Kusunoki, K. Otsuka, S. Satoh, M. Niwa, H. Senoh, and H. Fujiwara. 1994. T cell activation-associated hepatic injury: mediation by tumor necrosis factors and protection by interleukin 6. J. Exp. Med. 179:1529.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 1529
-
-
Mizuhara, H.1
O'Neill, E.2
Seki, N.3
Ogawa, T.4
Kusunoki, C.5
Otsuka, K.6
Satoh, S.7
Niwa, M.8
Senoh, H.9
Fujiwara, H.10
-
12
-
-
0028795171
-
Concanavalin A-induced T-cell mediated hepatic injury in mice: The role of tumor necrosis factor
-
Gantner, F., M. Leist, A. W. Lohse, P. G. Germann, and G. Tiegs. 1996. Concanavalin A-induced T-cell mediated hepatic injury in mice: the role of tumor necrosis factor. Hepatology 21:190.
-
(1996)
Hepatology
, vol.21
, pp. 190
-
-
Gantner, F.1
Leist, M.2
Lohse, A.W.3
Germann, P.G.4
Tiegs, G.5
-
13
-
-
0028110928
-
Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity
-
Kägi, D., F. Vignaux, B. Ledermann, K. Bürki, V. Depraetere, S. Nagata, H. Hengartner, and P. Golstein. 1994. Fas and perforin pathways as major mechanisms of T cell-mediated cytotoxicity. Science 265:528.
-
(1994)
Science
, vol.265
, pp. 528
-
-
Kägi, D.1
Vignaux, F.2
Ledermann, B.3
Bürki, K.4
Depraetere, V.5
Nagata, S.6
Hengartner, H.7
Golstein, P.8
-
14
-
-
0027937745
-
Cytolytic T-cell cytotoxicity is mediated through perform and Fas lytic pathways
-
Lowin, B., M. Hahne, C. Mattmann, and J. Tschopp. 1994. Cytolytic T-cell cytotoxicity is mediated through perform and Fas lytic pathways. Nature 370:650.
-
(1994)
Nature
, vol.370
, pp. 650
-
-
Lowin, B.1
Hahne, M.2
Mattmann, C.3
Tschopp, J.4
-
15
-
-
0028219791
-
Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice
-
Kägi, D., B. Ledermann, K. Bürki, P. Seiler, B. Odermatt, K. J. Olsen, E. R. Podack, R. M. Zinkernagel, and H. Hengartner. 1994. Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice. Nature 369:31.
-
(1994)
Nature
, vol.369
, pp. 31
-
-
Kägi, D.1
Ledermann, B.2
Bürki, K.3
Seiler, P.4
Odermatt, B.5
Olsen, K.J.6
Podack, E.R.7
Zinkernagel, R.M.8
Hengartner, H.9
-
16
-
-
0028110345
-
Immune function in mice lacking the perform gene
-
Walsh, C. M., M. Matloubian, C.-C. Liu, R. Ueda, C. G. Kurahara, J. L. Christensen, M. T. Huang, J. D.-E. Young, R. Ahmed, and W. R. Clark. 1994. Immune function in mice lacking the perform gene. Proc. Natl. Acad. Sci. USA 91:10854.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 10854
-
-
Walsh, C.M.1
Matloubian, M.2
Liu, C.-C.3
Ueda, R.4
Kurahara, C.G.5
Christensen, J.L.6
Huang, M.T.7
Young, J.D.-E.8
Ahmed, R.9
Clark, W.R.10
-
17
-
-
0027291205
-
Lethal effect of the anti-Fas antibody in mice
-
Ogasawara, J., R. Watanabe-Fukunaga, M. Adachi, A. Matsuzawa, T. Kasugai, Y. Kitamura, N. Itoh, T. Suda, and S. Nagata. 1993. Lethal effect of the anti-Fas antibody in mice. Nature 364:806.
-
(1993)
Nature
, vol.364
, pp. 806
-
-
Ogasawara, J.1
Watanabe-Fukunaga, R.2
Adachi, M.3
Matsuzawa, A.4
Kasugai, T.5
Kitamura, Y.6
Itoh, N.7
Suda, T.8
Nagata, S.9
-
18
-
-
0029130068
-
High level hepatitis B virus replication in transgenic mice
-
Guidotti, L. G., B. Matzke, H. Schaller, and F. V. Chisari. 1995. High level hepatitis B virus replication in transgenic mice. J. Virol. 69:6158.
-
(1995)
J. Virol.
, vol.69
, pp. 6158
-
-
Guidotti, L.G.1
Matzke, B.2
Schaller, H.3
Chisari, F.V.4
-
19
-
-
0023037176
-
Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice
-
Chisari, F. V., P. Filippi, A. McLachlan, D. R. Milich, M. Riggs, S. Lee, R. D. Palmiter, C. A. Pinkert, and R. L. Brinster. 1986. Expression of hepatitis B virus large envelope polypeptide inhibits hepatitis B surface antigen secretion in transgenic mice. J. Virol. 60:880.
-
(1986)
J. Virol.
, vol.60
, pp. 880
-
-
Chisari, F.V.1
Filippi, P.2
McLachlan, A.3
Milich, D.R.4
Riggs, M.5
Lee, S.6
Palmiter, R.D.7
Pinkert, C.A.8
Brinster, R.L.9
-
20
-
-
0021964206
-
Complete development of hepatic stages of Plasmodium falcinarum in vitro
-
Mazier, D., R. L. Beaudom, S. Mellouk, P. Druilhe, B. Texier, J. Trosper, F. Miltgen, I. Landau, C. Paul, O. Brandicourt, C. Guguen-Guillouzo, P. Langlois, and M. Gentilini. 1985. Complete development of hepatic stages of Plasmodium falcinarum in vitro. Science 227:440.
-
(1985)
Science
, vol.227
, pp. 440
-
-
Mazier, D.1
Beaudom, R.L.2
Mellouk, S.3
Druilhe, P.4
Texier, B.5
Trosper, J.6
Miltgen, F.7
Landau, I.8
Paul, C.9
Brandicourt, O.10
Guguen-Guillouzo, C.11
Langlois, P.12
Gentilini, M.13
-
21
-
-
0028223847
-
Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand
-
Takahashi, T., M. Tanaka, C. I. Brannan, N. A. Jenkins, N. G. Copeland, T. Suda, and S. Nagata. 1994. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76:969.
-
(1994)
Cell
, vol.76
, pp. 969
-
-
Takahashi, T.1
Tanaka, M.2
Brannan, C.I.3
Jenkins, N.A.4
Copeland, N.G.5
Suda, T.6
Nagata, S.7
-
22
-
-
0028266697
-
gld/gld mice are unable to express a functional ligand for Fas
-
Ramsdell, F., M. S. Seaman, R. E. Miller, T. W. Tough, M. R. Alderson. and D. H. Lynch. 1994. gld/gld mice are unable to express a functional ligand for Fas. Eur. J. Immunol. 24:928.
-
(1994)
Eur. J. Immunol.
, vol.24
, pp. 928
-
-
Ramsdell, F.1
Seaman, M.S.2
Miller, R.E.3
Tough, T.W.4
Alderson, M.R.5
Lynch, D.H.6
-
23
-
-
0027400726
-
Multiple defects of immune cell function in mice with disrupted interferon-γ genes
-
Dalton, D. K., S. Pitts-Meek, S. Keshav, I. S. Figari, A. Bradley, and T. A. Stewart. 1993. Multiple defects of immune cell function in mice with disrupted interferon-γ genes. Science 259:1739.
-
(1993)
Science
, vol.259
, pp. 1739
-
-
Dalton, D.K.1
Pitts-Meek, S.2
Keshav, S.3
Figari, I.S.4
Bradley, A.5
Stewart, T.A.6
-
24
-
-
0025087733
-
+ T cell from young and aged mice
-
+ T cell from young and aged mice. J. Immunol. 145:1295.
-
(1990)
J. Immunol.
, vol.145
, pp. 1295
-
-
Ernst, D.N.1
Hobbs, M.V.2
Torbett, B.E.3
Glasebrook, A.L.4
Rehse, M.A.5
Bottomly, K.6
Hayakawa, K.7
Hardy, R.R.8
Weigle, W.O.9
-
25
-
-
0027159596
-
Patterns of cytokine gene expression by CD4 T cells from young and old mice
-
Hobbs, M. V., W. O. Weigle, D. J. Noonan, B. E. Torbett, R. J. McEvilly, R. J. Koch, G. J. Cardenas, and D. N. Ernst. 1993. Patterns of cytokine gene expression by CD4 T cells from young and old mice. J. Immunol. 150:3602.
-
(1993)
J. Immunol.
, vol.150
, pp. 3602
-
-
Hobbs, M.V.1
Weigle, W.O.2
Noonan, D.J.3
Torbett, B.E.4
McEvilly, R.J.5
Koch, R.J.6
Cardenas, G.J.7
Ernst, D.N.8
-
26
-
-
0024362683
-
Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factor
-
Sheehan, K. C. F., N. H. Ruddle, and R. D. Schreiber. 1989. Generation and characterization of hamster monoclonal antibodies that neutralize murine tumor necrosis factor. J. Immunol. 142:3884.
-
(1989)
J. Immunol.
, vol.142
, pp. 3884
-
-
Sheehan, K.C.F.1
Ruddle, N.H.2
Schreiber, R.D.3
-
27
-
-
0021919834
-
Monoclonal antibodies to murine γ-interferon which differentially modulate macrophage activation and antiviral activities
-
Schreiber, R. D., L. J. Hicks, A. Celada, N. A. Buchmeier, and P. W. Gray. 1985. Monoclonal antibodies to murine γ-interferon which differentially modulate macrophage activation and antiviral activities. J. Immunol. 134:1609.
-
(1985)
J. Immunol.
, vol.134
, pp. 1609
-
-
Schreiber, R.D.1
Hicks, L.J.2
Celada, A.3
Buchmeier, N.A.4
Gray, P.W.5
-
29
-
-
0030005837
-
Concanamycin A, a powerful tool for characterization and estimation of contribution of perform- and Fas-based lytic pathways in cell-mediated cytotoxicity
-
Kataoka, T., N. Shinohara, H. Takayama, K. Takaku, S. Kondo, S. Yonehara, and K. Nagai. 1996. Concanamycin A, a powerful tool for characterization and estimation of contribution of perform- and Fas-based lytic pathways in cell-mediated cytotoxicity. J. Immunol. 156:3678.
-
(1996)
J. Immunol.
, vol.156
, pp. 3678
-
-
Kataoka, T.1
Shinohara, N.2
Takayama, H.3
Takaku, K.4
Kondo, S.5
Yonehara, S.6
Nagai, K.7
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