Intermediate TCR Cells in Mouse Lung: Their Effector Function to Induce Pneumonitis in Mice with Autoimmune-Like Graft-Versus-Host Disease

Journal of Immunology

Volumn 158, Issue 12, 1997, Pages 5805-5814

  Watanabe, Takehiro ^a   Kawamura, Toshihiko ^a   Kawamura, Hiroki ^a   Haga, Manabu ^a   Shirai, Katsuaki ^a   Watanabe, Hisami ^a   Eguchi, Shoji ^a   Abo, Toru ^a  

^a NIIGATA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIGEN;

ADOPTIVE TRANSFER; ANIMAL; ARTICLE; AUTOIMMUNE DISEASE; BAGG ALBINO MOUSE; C57BL MOUSE; GRAFT VERSUS HOST REACTION; IMMUNOLOGY; LUNG; LUNG DISEASE; MOUSE; NUDE MOUSE; PHENOTYPE;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS, CD3; AUTOIMMUNE DISEASES; GRAFT VS HOST DISEASE; LUNG; LUNG DISEASES; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, NUDE; PHENOTYPE;

EID: 0031570445     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (46)

1. Kadima-Nzuji, M., and J. E. Craighead. 1990. T-lymphocyte effects on murine cytomegalovirus pulmonary infection. Am. J. Pathol 137:907.
2. Graham, B. S., L A. Bunton, P. F. Wright, and D. T. Karzon. 1991. Role of T lymphocyte subsets in the pathogenesis of primary infection and rechallenge with respiratory syncytial virus in mice. J. Clin. Invest. 88:1026.
3. Schuyler, M., K. Gott, B. Edwards, and K. J. Nikula. 1994. Experimental hypersensitivity pneumonitis: effect of CD4 cell depletion. Am. J. Respir. Crit. Care. Med. 149:1286.
4. Ibraghimov, A. R., and R. G. Lynch. 1994. T cell specialization at environmental interfaces: T cells from the lung and the female genital tract of lpr and gld mice differ from their splenic and lymph node counterparts. Eur. J. Immunol. 24:1848.
5. Seki, S., T. Abo, T. Ohteki, K. Sugiura, and K. Kumagai. 1991. Unusual αβ-T cells expanded in autoimmune lpr mice are probably a counterpart of normal T cells in the liver. J. Immunol. 147:1214.
6. Abo,. T., T. Ohteki, S. Seki, N. Koyamada, Y. Yoshikai, T. Masuda, H. Rikiishi, and K. Kumagai. 1991. The appearance of T cells bearing self-reactive T cell receptor in the livers of mice injected with bacteria. J. Exp. Med. 174:417.
7. Okuyama, R., T. Abo, S. Seki, T. Ohteki, K. Sugiura, A. Kusumi, and K. Kumagai. 1992. Estrogen administration activales extrathymic T cell differentiation in the liver. J. Exp. Med. 175:661.
8. Iiai, T., H. Watanabe, S. Seki, K. Sugiura, K. Hirokawa, M. Utsuyama, H. Takahashi-Iwanaga, T. Iwanaga, T. Ohteki, and T. Abo. 1992. Ontogeny and development of extrathymic T cells in mouse liver. Immunology 77:556.
9. Ohtsuka, K., T. Iiai, H. Watanabe, T. Tanaka, M. Miyasaka, K. Sato, H. Asakura, and T. Abo. 1994. Similarities and differences between extrathymic T cells residing in mouse liver and intestine. Cell. Immunol. 153:52.
10. Seki, S., D. H. Kono, R. S. Balderas, and A. N. Theofilopoulos. 1994. Vβ repertoire of murine hepatic T cells. J. Immunol. 153:637.
11. + cells expressing intermediate levels of the T cell receptor in the liver and other immune organs. Eur. J. Immunol. 25:2272.
12. Sato, K., K. Ohtsuka, K. Hasegawa, S. Yamagiwa, H. Watanabe, T. Iwanaga, H. Takahashi-Iwanaga, H. Asakura, and T. Abo. 1995. Evidence for extrathymic generation of intermediate TCR cells in the liver revealed in thymectomized, irradiated mice subjected to bone marrow transplantation. J. Exp. Med. 182:759.
13. + cells are present within a population of intermediate TCR cells. J. Immunol. 155:2972.
14. Kawachi, Y., K. Arai, T. Moroda, T. Kawamura, H. Umezu, M. Naito, K. Ohtsuka, K. Hasegawa, H. Takahashi-Iwanaga, T. Iwanaga, L. D. Shults, H. Watanabe, and T. Abo. 1995. Supportive cellular elements for hepatic T cell differentiation: T cells expressing intermediate levels of the T cell receptor are cytotoxic against syngeneic hepatoma, and are lost after hepatocyte damage. Eur. J. Immunol. 25:3452.
15. Bandeira, A., S. Itohara, M. Bonneville, O. Burlen-Defranoux, T. Mota-Santos, A. Coutinho, S. Tonegawa. 1991. Extrathymic origin of intestinal lymphocytes bearing T-cell antigen receptor γδ. Proc. Natl. Acad. Sci. USA 88:43.
16. + lymphocyte populations with different T cell receptors: a role for the gut epithelium in T cell differentiation. J. Exp. Med. 173:471.
17. Guy-Grand, D., M. Malassis-Seris, C. Briottel, and P. Vassalli. 1991. Cytotoxic differentiation of mouse gut thymodependent and independent intraepithelial T lymphocytes is induced locally: correlation between functional assays, presence of perform and granzyme transcripts, and cytoplasmic granules. J. Exp. Med. 171:1549.
18. + lymphocytes reveals a major extrathymic pathway of T cell differentiation. J. Exp. Med. 173:483.
19. Andreu-Sánchez, J. L., I. M. de Alborán, M. A. R. Marcos, A. Sánchez-Movilla, C. Martínez-A., and G. Kroemer. 1991. Interleukin 2 abrogates the nonresponsive state of T cells expressing a forbidden T cell receptor repertoire and induces autoimmune disease in neonatally thymectomized mice. J. Exp. Med. 173:1323.
20. Ishikawa, H., and K. Saito. 1980. Congenially athymic nude (nu/nu) mice have Thy-1-bearing immunocompetent helper T cells in their peritoneal cavity. J. Exp. Med. 151:965.
21. Elbe, A., O. Kilgus, R. Strohal, E. Payer, S. Schreiber, and G. Stingl. 1992. Fetal skin: a site of dendritic epidermal T cell development. J. Immunol. 149:1694.
22. - skin intraepithelial lymphocytes in radiation bone marrow chimeras. J. Immunol. 151:3000.
23. Hayakawa, S., S. Saito, N. Nemoto, F. Chishima, K. Akiyama, H. Shiraishi, J. Hayakawa, M. Karasaki-Suzuki, K. T. Fujii, M. Ichijo, I. Sakurai, and K. Satoh. 1994. Expression of recombinase-activating genes (RAG-1 and 2) in human decidual mononuclear cells. J. Immunol. 153:4934.
24. Kimura, M., H. Hanawa, H. Watanabe, M. Ogawa, and T. Abo. 1995. Synchronous expansion of intermediate TCR cells in the liver and uterus during pregnancy. Cell. Immunol. 162:16.
25. Ikarashi, Y., T. Abo, K. Kawai, T. Iiai, H. Watanabe, K. Suzuki, Y. Matsumoto, S. Omata, and M. Fujiwara. 1994. Expansion of intermediate T-cell receptor cells in mice with autoimmune-like graft-versus-host disease. Immunology 83:205.
26. + stem cells and thymocyte precursors in the livers of adult mice. J. Exp. Med. 184:687.
27. Watanabe, H., K. Ohtsuka, M. Kimura, Y. Ikarashi, K. Ohmori, A. Kusumi, T. Ohteki, S. Seki, and T. Abo. 1992. Details of an isolation method for hepatic lymphocytes in mice. J. Immunol. Methods 146:145.
28. Goossens, P. L., H. Jouin, G. Marchal, and G. Milon. 1990. Isolation and flow cytometric analysis of the free lymphomyeloid cells present in murine liver. J. Immunol. Methods 132:137.
29. Watanabe, H,. T. Iiai, M. Kimura, K. Ohtsuka, T. Tanaka, M. Miyasaka, M. Tsuchida, H. Hanawa, and T. Abo. 1993. Characterization of intermediate TCR cells in the liver of mice with respect to their unique IL-2R expression. Cell. Immunol. 149:331.
30. Budd, R. C., G. C. Miescher, R. C. Howe, R. K, Lees, C. Bron, and H. R. MacDonald. 1987. Developmentally regulated expression of T cell receptor β chain variable domains in immature thymocytes. J. Exp. Med. 166:577.
31. - thymocytes. Nature 329:336.
32. Fowlkes, B. J., A. M. Kruisbeek. H. Ton-That, M. A. Weston, J. E. Coligan, R. H. Schwartz, and D. M. Pardoll. 1987. A novel population of T-cell receptor αβ-bearing thymocytes which predominantly expresses a single Vβ gene family. Nature 329:251.
33. - thymocytes. Int. Immunol. 2:407.
34. - thymocytes. Int. Immunol. 2:157.
35. + thymocytes. J. Immunol. 146:1113.
36. + thymocytes: variable influence of self-antigens on T cell receptor Vβ usage. J. Immunol. 146:1134.
37. Ohtsuka, K., K. Hasegawa, K. Sato, K. Arai, H. Watanabe, H. Asakura, and T. Abo. 1994. A similar expression pattern of adhesion molecules between intermediate TCR cells in the liver and intraepithelial lymphocytes in the intestine. Microbiol. Immunol. 38:677.
38. Renz, H., J. Saloga, K. L. Bradley, J. E. Loader, J. L. Greenstein, G. Larsen, and E. W. Gelfand. 1993. Specific Vβ T cell subsets mediate the immediate hypersensitivity response to ragweed allergen. J. Immunol. 151:1907.
39. a haplotype. J. Immunol. 144:3473.
40. - subsets, using Fas ligand/Fas molecules. Immunology. In press.
41. + cells. Curr. Opin. Immunol. 7:367.
42. + cells: new clues to their origin, specificity, and function. J. Exp. Med. 182:633.
43. Bix, M., and R. M. Locksley. 1995. Natural T cells: cells that co-express NKPP-1 and TCR. J. Immunol 155:1020.
44. + T cells: a new family of T cells. Immunol. Today 17:71.
45. intermediate T cells in the liver of normal adult mice: implication for lpr pathogenesis. Int. Immunol. 6:533.
46. Crispe, N. I., and L. Huang. 1994. Neonatal, moribund and undead T cells: the role of the liver in T cell development. Semin. Immunol. 6:39.