Genomic structure, evolution, and expression of human FLII, a gelsolin and leucine-rich-repeat family member: Overlap with LLGL

Genomics

Volumn 42, Issue 1, 1997, Pages 46-54

  Campbell, Hugh D ^a,e   Fountain, Shelley ^e   Young, Ian G ^b   Claudianos, Charles ^a   Hoheisel, Jörg D ^c   Chen, Ken Shiung ^d   Lupski, James R ^d  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

^b Biology and Environment   (Australia)

^c GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^d BAYLOR COLLEGE OF MEDICINE   (United States)

^e AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIN BINDING PROTEIN; GELSOLIN; LEUCINE; POLYADENYLIC ACID;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ARTICLE; DROSOPHILA MELANOGASTER; EMBRYO DEVELOPMENT; EVOLUTION; FLIGHT MUSCLE; GENE EXPRESSION; GENE SEQUENCE; GENE STRUCTURE; GENETIC ANALYSIS; INTRON; MOLECULAR CLONING; MULTIGENE FAMILY; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SEQUENCE ANALYSIS; SMITH MAGENIS SYNDROME; SOUTHERN BLOTTING; TATA BOX;

CAENORHABDITIS ELEGANS; DROSOPHILA MELANOGASTER; MELANOGASTER;

EID: 0031570341     PISSN: 08887543     EISSN: None     Source Type: Journal    
DOI: 10.1006/geno.1997.4709     Document Type: Article

References (38)

1. Bazari, W. L., Matsudaira, P., Wallek, M., Smeal, T., Jakes, R., and Ahmed, Y. (1988). Villin sequence and peptide map identify six homologous domains. Proc. Natl. Acad. Sci. USA 85: 4986-4990.
2. Bristow, J., Tee, M. K, Gitelman, S. E., Mellon, S. H., and Miller, W. L. (1993). Tenascin-X: A novel extracellular matrix protein encoded by the human XB gene overlapping P450c21B. J. Cell Biol. 122: 265-278.
3. Campbell, H. D., Schimansky, T., Claudianos, C., Ozsarac, N., Kasprzak, A. B., Cotsell, J. N., Young, I. G., de Couet, H. G., and Miklos, G. L. G. (1993). The Drosophila melanogaster flightless-I gene involved in gastrulation and muscle degeneration encodes gelsolinlike and leucine-rich-repeat domains, and is conserved in Caenorhabditis elegans and human. Proc. Natl. Acad. Sci. USA 90: 11386-11390.
4. Chen, K-S., Gunaratne, P. H., Hoheisel, J. D., Young, I. G., Miklos, G. L. G., Greenberg, F., Shaffer, L. G., Campbell, H. D., and Lupski, J. R. (1995). The human homologue of the Drosophila melanogaster flightless-I gene (fliI) maps within the Smith-Magenis microdeletion critical region in 17p11.2. Am. J. Hum. Genet. 56:175-182.
5. Claudianos, C., and Campbell, H. D. (1995). The novel flightless-I gene brings together two gene families, actin binding proteins related to gelsolin and leucine-rich-repeat proteins involved in ras signal transduction. Mol. Biol. Evol. 12: 405-414.
6. Cross, S. H., Charlton, J. C., Nan, X., and Bird, A. P. (1994). Purification of CpG islands using a methylated DNA binding column. Nature Genet. 6: 236-244.
7. de Couet, H. G., Fong, K. S. K., Weeds, A. G., McLaughlin, P. J., and Miklos, G. L. G. (1995). Molecular and mutational analysis of a gelsolin-family member encoded by the flightless I gene of Drosophila melanogaster. Genetics 141: 1049-1059.
8. Deak, I. I., Bellamy, P. R., Bienz, M., Dubuis, Y., Fenner, E., Gollin, M., Rähmi, A., Ramp, T., Reinhardt, C. A., and Cotton, B. (1982). Mutations affecting the indirect flight muscles of Drosophila melanogaster. J. Embryol. Exp. Morphol. 69: 61-81.
9. Deininger, P. (1983). Random subcloning of sonicated DNA: Application to shotgun DNA sequence analysis. Anal. Biochem. 129: 216-223.
10. Devereux, J., Haeberli, P., and Smithies, O. (1984). A comprehensive set of sequence analysis programs for the VAX. Nucleic Acids Res. 12: 387-395.
11. Felsenstein, J. (1993). PHYLIP - Phylogeny inference package, University of Washington, Seattle, WA.
12. Hartwig, J., and Kwiatkowski, D. (1991). Actin-binding proteins. Curr. Opin. Cell Biol. 3: 87-97.
13. Hoffman, A., Noegel, A.A., Bomblies, L., Lottspeich, F., and Schleicher, M. (1993). The 100kDa F-actin capping protein of Dictyostelium amoebae is a villin prototype ('protovillin'). FEBS Lett. 328: 71-76.
14. Homyk, T., Jr., and Sheppard, D. E. (1977). Behavioral mutants of Drosophila melanogaster. I. Isolation and mapping of mutations which decrease flight ability. Genetics 87: 95-104.
15. Kallioniemi, O.-P., Kallioniemi, A., Mascio, L., Sudar, D., Pinkel, D., Deaven, L., and Gray, J. (1994). Physical mapping of chromosome 17 cosmids by fluorescence in situ hybridization and digital image analysis. Genomics 20: 125-128.
16. Kobe, B., and Deisenhofer, J. (1995). Proteins with leucine-rich repeats. Curr. Opin. Struct. Biol. 5: 409-416.
17. Koyama, K., Fukushima, Y., Inazawa, J., Tomotsune, D., Takahashi, N., and Nakamura, Y. (1996). The human homologue of the murine Llglh gene (LLGL) maps within the Smith-Magenis syndrome region in 17p11.2. Cytogenet. Cell Genet. 72: 78-82.
18. Kuwabara, K., Takahashi, Y., Tomotsune, D., Takahashi, N., and Kominami, R. (1994). mgl-1, a mouse homologue of the Drosophila tumor-suppressor gene l(2)gl, maps to chromosome 11. Genomics 20: 337-338.
19. Kwiatkowski, D. J., Mehl, R., and Yin, H. L. (1988). Genomic organization and biosynthesis of secreted and cytoplasmic forms of gelsolin. J. Cell Biol. 106: 375-384.
20. Mahajan-Miklos, S., and Cooley, L. (1994). The villin-like protein encoded by the Drosophila quail gene is required for actin bundle assembly during oogenesis. Cell 78: 291-301.
21. Mattick, J. (1994). Introns: Evolution and function. Curr. Opin. Cell Biol. 4: 823-831.
22. 2 and standby are members of the W-2 lethal complementation group at the base of the X-chromosome of Drosophila melanogaster. J. Neurogenet. 6: 133-151.
23. Mishra, V. S., Henske, E. P., Kwiatkowski, D. J., and Southwick, F. S. (1994). The human actin-regulatory protein Cap G: Gene structure and chromosome location. Genomics 23: 560-565.
24. Orloff, G. J., Allen, P. G., Miklos, G. L. G., Young, I. G., Campbell, H. D., and Kwiatkowski, D. J. (1995) Human flightless-I has actin binding ability. Mol. Biol. Cell 6: 139.
25. Perrimon, N., Smouse, D., and Miklos, G. L. G. (1989). Developmental genetics of loci at the base of the X chromosome of Drosophila melanogaster. Genetics 121: 313-331.
26. Pringault, E., Robine, S., and Louvard, D. (1991). Structure of the human villin gene. Proc. Natl. Acad. Sci. USA 88: 10811-10815.
27. Saitou, N., and Nei, M. (1987). The neighbor-joining method: A new method for reconstructing phylogenetic trees. Mol. Biol. Evol. 4: 406-425.
28. Sambrook, J., Fritsch, E. F., and Maniatis, T. (1989). "Molecular Cloning: A Laboratory Manual," 2nd ed., Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
29. Southwick, F. S. (1995). Gain-of-function mutations conferring actinsevering activity to human macrophage Cap G. J. Biol. Chem. 270: 45-48.
30. Staden, R. (1987). Computer handling of DNA sequencing projects. In "Nucleic Acid and Protein Sequence Analysis: a Practical Approach" (M. J. Bishop and C. J. Rawlings, Eds.), pp. 173-217, IRL Press, Oxford.
31. Strand, D., Unger, S., Corvi, R., Hartenstein, K., Schenkel, H., Kalmes, A., Merdes, G., Neumann, B., Krieg-Schneider, F., Coy, J. F., Poustka, A., Schwab, M., and Mechler, B. M. (1995). A human homologue of the Drosophila tumour suppressor gene l(2)gl maps to 17p11.2-12 and codes for a cytoskeletal protein that associates with nonmuscle myosin II heavy chain. Oncogene 11: 291-301.
32. Sulston, J., Du, Z., Thomas, K, Wilson, R., Hillier, L., Staden, R., Halloran, N., Green, P., Thierry-Mieg, J., Qiu, L., Dear, S., Coulson, A., Craxton, M., Durbin, R., Berks, M., Metzstein, M., Hawkins, T., Ainscough, R., and Waterston, R. (1992). The C. elegans genome sequencing project: A beginning. Nature 356: 37-41.
33. Swofford, D. (1993). PAUP: Phylogenetic analysis using parsimony, Version 3.1, Illinois Natural History Survey, Champaign, IL.
34. Tee, M. K., Thomson, A. A., Bristow, J., and Miller, W. L. (1995). Sequences promoting the transcription of the human XA gene overlapping P450c21A correctly predict the presence of a novel, adrenal-specific, truncated form of tenascin-X. Genomics 28: 171-178.
35. Tomotsune, D., Shoji, H., Wakamatsu, Y., Kondoh, H., and Takahashi, N. (1993). A mouse homologue of the Drosophila tumour-suppressor gene l(2)gl controlled by Hox-C8 in vivo. Nature 365: 69-72.
36. Way, M., and Weeds, A. (1988). Nucleotide sequence of pig plasma gelsolin. Comparison of protein sequence with human gelsolin and other actin-severing proteins shows strong homologies and evidence for large internal repeats. J. Mol. Biol. 203: 1127-1133.
37. Witke, W., Sharpe, A. H., Hartwig, J. H., Azuma, T., Stossel, T. P., and Kwiatkowski, D. J. (1995). Hemostatic, inflammatory, and fibroblast responses are blunted in mice lacking gelsolin. Cell 81: 41-51.
38. Zehetner, G., and Lehrach, H. (1994). The Reference Library System - sharing biological material and experimental data. Nature 367: 489-491.