Docking of verapamil in a synthetic Ca2+ channel: Formation of a ternary complex involving Ca2+ ions

Archives of Biochemistry and Biophysics

Volumn 341, Issue 2, 1997, Pages 238-244

  Zhorov, Boris S ^b   Ananthanarayanan, Vettai S ^a  

^a MCMASTER UNIVERSITY   (Canada)

^b SECHENOV INSTITUTE OF EVOLUTIONARY PHYSIOLOGY AND BIOCHEMISTRY   (Russian Federation)

Author keywords

calcium channel drug interaction; minimum energy conformation; Monte Carlo method; synthetic channel peptide; verapamil

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL BLOCKING AGENT; CALCIUM ION; DIHYDROPYRIDINE DERIVATIVE; DOCKING PROTEIN; ISOLEUCINE; SYNTHETIC PEPTIDE; VERAPAMIL;

ARTICLE; CHANNEL GATING; COMPLEX FORMATION; DRUG BINDING SITE; DRUG CONFORMATION; DRUG MECHANISM; HYDROPHOBICITY; LIGAND BINDING; LIPID BILAYER; PRIORITY JOURNAL; SYSTEM ANALYSIS;

EID: 0031570293     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1997.9968     Document Type: Article

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