Immunoregulatory Idiotypes Stimulate T Helper 1 Cytokine Responses in Experimental Schistosoma mansoni Infections

Journal of Immunology

Volumn 158, Issue 8, 1997, Pages 3800-3804

  Montesano, M Angela ^a,b   Freeman Jr , George L ^b   Secor, W Evan ^b,c   Colley, Daniel G ^b  

^a FEDERAL UNIVERSITY OF JUIZ DE FORA   (Brazil)

^b NATL CENTER FOR INFECTIOUS DISEASES   (United States)

^c CENTERS FOR DISEASE CONTROL AND PREVENTION   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIIDIOTYPIC ANTIBODY; CYTOKINE; HELMINTH ANTIBODY; IMMUNOGLOBULIN CLASS; IMMUNOLOGICAL ADJUVANT; PARASITE ANTIGEN;

ANIMAL; ARTICLE; CBA MOUSE; HUMAN; IMMUNOLOGY; MALE; MOUSE; SCHISTOSOMA MANSONI; TH1 CELL;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, ANTI-IDIOTYPIC; ANTIBODIES, HELMINTH; ANTIGENS, HELMINTH; CYTOKINES; HUMANS; IMMUNOGLOBULIN ISOTYPES; MALE; MICE; MICE, INBRED CBA; SCHISTOSOMA MANSONI; SCHISTOSOMIASIS MANSONI; TH1 CELLS;

EID: 0031569479     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (36)

1. Nash, T. E., A. W. Cheever, E. A. Ottesen, and J. A. Cook. 1982. Schistosoma infections in humans: perspectives and recent findings. Annu. Intern. Med. 97: 740.
2. Colley, D. G., A. A. Garcia, J. R. Lambertucci, J. C. Parra, N. Katz, R. S. Rocha, and G. Gazzinelli. 1986. Immune responses during human schistosomiasis. XII. Differential responsiveness in patients with hepatosplenic disease. Am. J. Trop. Med. Hyg. 35:793.
3. Colley, D. G. 1987. Dynamics of the human immune response to schistosomes. In Bailliere's Clinical Tropical Medicine and Communicable Diseases, Vol. 2, No. 2: Schistosomiasis. A. A. F. Mahmoud, ed. Bailliere Tindel, London, p. 315.
4. Gazzinelli, G., and D. G. Colley. 1992. Human immune responses during Schistosomiasis mansoni. Rev. Soc. Bras. Med. Trop. 25:125.
5. Montesano, M. A., M. S. Lima, R. Correa-Oliveira, G. Gazzinelli, and D. G. Colley. 1989. Immune response during human schistosomiasis mansoni. XVI. Idiotypic differences in antibody preparations from patients with different clinical forms of infection. J. Immunol. 142:2501.
6. Montesano, M. A., G. L. Freeman, Jr., G. Gazzinelli, and D. G. Colley. 1990. Immune responses during human Schistosoma mansoni. XVII. Recognition by monoclonal anti-idiotypic antibodies of several idiotopes on a monoclonal anti-soluble schistosomal egg antigen antibody and anti-soluble schistosomal egg antigen antibodies from patients with different clinical forms of infection. J. Immunol. 145:3095.
7. Parra, J. C., G. Gazzinelli, A. M. Goes, R. B. Moyes, R. Rocha, D. G. Colley, and B. L. Doughty. 1991. Granulomatous hypersensitivity to Schistosoma mansoni egg antigens in human schistosomiasis. II. In vitro granuloma modulation induced by polyclonal idiotypic antibodies. J. Immunol. 147:3949.
8. Henderson, G. S., N. A. Nix, M. A. Montesano, D. Gold, G. L. Freeman, Jr., T. McCurley, and D. G. Colley. 1993. Two distinct pathological syndromes in male CBA/J inbred mice with chronic Schistosoma mansoni infection. Am. J. Pathol. 142:703.
9. Colley, D. G., A. M. Goes, B. L. Doughty, R. Correa-Oliveira, J. C. Parra, K. M. Lairmore, M. A. Montesano, R. Rocha, and G. Gazzinelli. 1989. Antiidiotypic T cells and factors in murine and human schistosomiasis. In The Cellular Basis of Immune Modulation. J. G. Kaplan, D. R. Green, and R. C. Bleackly, eds. Alan R. Liss, Philadelphia, p. 367.
10. Montesano, M. A., G. L. Freeman, Jr., G. Gazzinelli, and D. G. Colley. 1990. Expression of cross-reactive, shared idiotypes on anti-SEA antibodies from humans and mice with schistosomiasis. J. Immunol. 145:1002.
11. Snapper, C. M., and J. J. Mond. 1993. Towards a comprehensive view of immunoglobulin class switching. Immunol. Today 14:15.
12. Mong-Shang, L., and C. Yung-Wu. 1993. B cell differentiation. II. Isotype potential of a single B cell. Cell. Immunol. 150:343.
13. Agrewala, J. N., P. S. Raghava, and G. C. Mishra. 1993. Measurement and computation of murine interleukin-4 and interferon-γ by exploiting the unique abilities of these lymphokines to induce the secretion of IgG1 and IgG2a. Immunoassay 14:83.
14. Morris, S. C., K. B. Madden, J. J. Adamovicz, W. C. Gause, B. R. Hubbard, M. K. Gately, and F. D. Finkelman. 1994. Effects of IL-12 on in vivo cytokine gene expression and Ig isotype selection. J. Immunol. 152:1047.
15. Carter, C. E., and D. G. Colley. 1978. An electrophoretic analysis of Schistosoma mansoni soluble egg antigenic preparation. J. Parasitol. 64:385.
16. Powell, M. R., and D. G. Colley. 1985. Demonstration of splenic auto-anti-idiotypic plaque-forming cells in mice infected with Schistosoma mansoni. J. Immunol. 134:4140.
17. Powell, M. R., and D. G. Colley. 1987. Anti-idiotypic T lymphocyte responsiveness in murine schistosomiasis mansoni. Cell. Immunol. 104:377.
18. Bosshardt, S. C., N. A. Nix, and D. G. Colley. 1996. Early development and progression of lymphocyte-stimulatory cross-reactive idiotypes expressed on antibodies to soluble egg antigens during Schistosoma mansoni infection of mice. Eur. J. Immunol. 26:272.
19. Grzych, J. M., M. Capron, P. H. Lambert, C. Dissous, S. Torres, and A. Capron. 1985. An anti-idiotype vaccine against experimental schistosomiasis. Nature 316: 74.
20. Phillips, S. M., E. G. Fox, N. G. Fathelbab, and D. Walker. 1986. Epitopic and paratopically directed anti-idiotypic factors in the regulation of resistance to murine schistosomiasis mansoni. J. Immunol. 137:2339.
21. Percy, J. C., and D. A. Harn. 1988. Monoclonal anti-idiotypic and anti-anti-idiotypic antibodies from mice immunized with a protective monoclonal antibody against Schistosoma mansoni. J. Immunol. 140:2760.
22. Phillips, S. M., P. J. Perrin, N. G. Fathelbab, G. P. Linenette, and M. A. Idris. 1988. The regulation of resistance to Schistosoma mansoni by auto-anti-idiotypic immunity. J. Immunol. 141:1728.
23. Kresina, T. F., and G. R. Olds. 1989. Antiidiotypic antibody vaccine in murine Schistosomiasis mansoni comprising the internal image of antigens. J. Clin. Invest. 83:912.
24. Abe, T., and D. G. Colley. 1984. Modulation of Schistosoma mansoni egg-induced granuloma formation. III. Evidence for an anti-idiotypic, I-J positive, I-J restricted, soluble T suppressor factor. J. Immunol. 132:2084.
25. Doughty, B. L., A. M. Goes, J. Parra, R. Rocha, C. Cone, D. G. Colley, and G. Gazzinelli. 1989. Anti-idiotypic T cells in human schistosomiasis. Immunol. Invest. 18:373.
26. Freeman, G. L., Jr., M. A. Montesano, W. E. Secor, D. G. Colley, M. J. Howard, and S. C. Bosshardt. 1996. Immunopathogenesis and immunoregulation in schistosomiasis: distinct chronic pathologic syndromes in CBA/J mice. Ann. NY Acad. Sci. 797:151.
27. Grzych, J. M., E. J. Pearce, A. Cheever, Z. A. Caulada, P. Caspar, S. Hieny, F. Lewis, and A. Sher. 1991. Egg deposition is the major stimulus for the production of Th2 cytokines in murine Schistosomiasis mansoni. J. Immunol. 146: 1322.
28. + T lymphocytes correlates with down-regulation of Th1 cytokine synthesis in helminth infection. J. Immunol. 147:2713.
29. Pearce, E. J., P. Caspar, J. M. Grzych, F. A. Lewis, and A. Sher. 1992. Down-regulation of Th1 cytokine production accompanies induction of Th2 responses by parasitic helminth, Schistosoma mansoni. J. Immunol. 146:1322.
30. Henderson, G. S., X. Lu, T. L. McCurley, and D. G. Colley. 1992. In vivo molecular analysis of lymphokines involved in the murine immune response during Schistosoma mansoni infection. II. Quantification of IL-4 mRNA, IFN-γ mRNA, and IL-2 mRNA levels in the granulomatous livers, mesenteric lymph nodes, and spleens during the course of modulation. J. Immunol. 148:2261.
31. Chensue, S. W., P. D. Terebuh, K. S. Warmington, S. D. Hershey, H. L. Evanoff, S. L. Kunkel, and G. I. Higashi. 1992. Role of IL-4 and IFN-γ in Schistosoma mansoni egg-induced hypersensitivity granuloma formation: orchestration, relative contribution, and relationship to macrophage function. J. Immunol. 148:900.
32. Chensue, S. W., K. S. Warmington, J. Ruth, P. M. Lincoln, and S. L. Kunkel. 1994. Cross-regulatory role of interferon-gamma (IFN-gamma), IL-4 and IL-10 in schistosome egg granuloma formation: in vivo regulation of Th activity and inflammation. Clin. Exp. Immunol. 98:395.
33. Adewusi, O. I., N. A. Nix, X. Lu, D. G. Colley, and W. E. Secor. 1996. Schistosoma mansoni: relationship of tumor necrosis factor-alpha to morbidity and collagen deposition in chronic experimental infection. Exp. Parasitol. 84:115.
34. Lukacs, N. W., and D. L. Boros. 1993. Lymphokine regulation of granuloma formation in murine Schistosomiasis mansoni. Clin. Immunol. Immunopathol. 68:57.
35. Wynn, T. A., I. Eltoum, I. P. Oswald, A. W. Cheever, and A. Sher. 1994. Endogenous interleukin 12 (IL-12) regulates granuloma formation induced by eggs of Schistosoma mansoni and exogenous IL-12 both inhibits and prophylactically immunizes against egg pathology. J. Exp. Med. 179:1551.
36. Jankovic, D., M. Kullberg, G. Yap, M. Epstein, A. Cheever, and A. Sher. 1996. B cell-deficient mice exposed to Schistosoma mansoni develop exacerbated egg pathology which fails to down-modulate during chronic infection. FASEB J. A1345:1995 (Abstr.).