Development of IFN-γ-Producing CD8+γδ+ T Lymphocytes and IL-2-Producing CD4+αβ+ T Lymphocytes during Contact Sensitivity

Journal of Immunology

Volumn 158, Issue 6, 1997, Pages 2567-2575

  Dieli, Francesco ^a   Asherson, Geoffrey L ^b   Sireci, Guido ^a   Dominici, Roberto ^a   Sciré, Elisabetta ^a   Salerno, Alfredo ^a  

^a UNIVERSITY OF PALERMO   (Italy)

^b UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; GAMMA INTERFERON; INTERLEUKIN 2; LYMPHOCYTE ANTIGEN RECEPTOR; MONOCLONAL ANTIBODY;

A J MOUSE; ANIMAL; ARTICLE; BAGG ALBINO MOUSE; BIOSYNTHESIS; C3H MOUSE; CBA MOUSE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CLASSIFICATION; CONTACT DERMATITIS; GENETICS; IMMUNOLOGY; IMMUNOPHENOTYPING; LYMPHOCYTE ACTIVATION; METABOLISM; MOUSE; TIME;

ANIMALS; ANTIBODIES, MONOCLONAL; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DERMATITIS, CONTACT; EPITOPES; IMMUNOPHENOTYPING; INTERFERON TYPE II; INTERLEUKIN-2; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED A; MICE, INBRED BALB C; MICE, INBRED C3H; MICE, INBRED CBA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; TIME FACTORS;

EID: 0031569125     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (44)

1. Turk, J. L. 1980. Delayed Hypersensitivity, 2nd Ed, North-Holland, Amsterdam, p. 71.
2. Friedman, P. S. 1989. Contact sensitivity. Curr. Opin. Immunol. 1:690.
3. Cher, D. J., and T. R. Mosmann. 1987. Two types of murine leper T cell clone. II. Delayed type hpersensitivity is mediated by Th1 clones. J. Immunol. 138: 3688.
4. Fong, T. A. T., and T. R. Mosmann. 1989. The role of IFN-gamma in delayed-type hypersensitivity mediated by Th1 clones. J. Immunol. 143:2887.
5. +) in classical delayed-type (tuberculin) hypersensitivity reactions in human skin. J. Immunol. 148:2058.
6. Hasmid, Q., M. Boguniewicz, and D. J. Leung. 1994. Differential in situ cytokine gene expression in acute versus chronic atopic dermatitis. J. Clin. Invest. 94:870.
7. Heinzel, F. P., M. D. Sadick, B. J. Holoday, R. L. Coffman, and R. M. Locksley. 1989. Reciprocal expression of interferon gamma or interleukin 4 during the resolution or progression of murine leishmaniasis: evidence for expansion of distinct helper T cell subsets. J. Exp. Med. 169:59.
8. Titus, R. G., R. Ceredig, J. C. Cerottini, and J. A. Louis. 1985. Therapeutic effect of anti-L3T4 monoclonal antibody GK1.5 on cutaneous leishmaniasis in genetically-susceptible BALB/c mice. J. Immunol. 135:2108.
9. Enk, A. H., and S. I. Katz. 1992. Early molecular events in the induction phase of contact sensitivity. Proc. Natl. Acad. Sci. USA 89:1398.
10. Enk, A. H., V. L. Angeloni, M. C. Urdey, and S. I. Katz. 1993. An essential role for Langherans cell-derived IL-1β in the initiation of primary immune response in skin. J. Immunol. 151:2184.
11. Piguet, P. F., G. E. Grau, C. Hauser, and P. Vassalli. 1991. Tumor necrosis factor is a critical mediator in hapten-induced and irritant contact hypersensitivity. J. Exp. Med. 173:673.
12. Dieli, F., G. L. Asherson, G. Colonna Romano, G. Sireci, F. Gervasi, and A. Salerno. 1994. IL-4 is essential for the systemic transfer of delayed hyper-sensitivity by T cell lines: role of γδ cells. J. Immunol. 152:2698.
13. Salerno, A., F. Dieli, G. Sireci, A. Bellavia, and G. L. Asherson. 1995. Interleukin-4 is a critical cytokine in contact sensitivity. Immunology 84:404.
14. d haplotype determines poor interferon-γ response to several antigens. Eur. J. Immunol. 20:1305.
15. Dieli, F., G. L. Asherson, C. T. Bonanno, G. Sireci, and A. Salerno. 1995. Major hystocompatibility complex regulation of the class of the immune response to the hapten TNP. Immunology 84:355.
16. Ptak, W., and P. W. Askenase. 1992. Gamma/delta T cells assist alpha/beta T cells in adoptive transfer of contact sensitivity. J. Immunol. 149:3503.
17. + T cells. Immunology 76:427.
18. Klein, J., F. Figueroa, and D. Klein. 1982. H-2 haplotypes, genes and antigens: second listing. Immunogenetics 16:285.
19. Morris, A. G., and G. A. Ward. 1987. In Lymphokines and Interferons: Practical Approach. M. J. Clemens, A. G. Morris, and A. J. H. Gearing, eds. IRL Press, Oxford, U.K., p. 61.
20. + T cells. Int. Immunol. 5:977.
21. Spitalny, G., and E. Havell. 1984. Monoclonal antibody to murine gamma interferon inhibits lymphokine-induced antiviral and macrophage tumoricidal activity. J. Exp. Med. 159:1560.
22. Thomson, J. A., A. B. Troutt, and A. Kelso. 1993. Contact sensitization to oxazolone: involvement of both interferon-γ and interleukin-4 in oxazolone-specific Ig and T-cell response. Immunology 78:185.
23. + T cells in murine contact sensitivity revealed by in vivo monoclonal antibody depletion. J. Immunol. 144:4121.
24. Askenase, P. W., M. Szczepanik, M. Ptak, and W. Ptak. 1995. γδ T cells in normal spleen assist immunized αβ T cells in the adoptive cell transfer of contact sensitivity: effect of Bordetella pertussis, cyclophosphamide, and anti-suppressor cell antibodies. J. Immunol. 154:3644.
25. Ptak, W., M. Szczepanik, R. Ramabhadran, and P. W. Askenase. 1996. Immune or norma γδ T cells that assist αβ T cells in elicitation of contact sensitivity preferentially use Vγ5 and Vδ4 variable region gene segments. J. Immunol. 156: 976.
26. Haas, W., P. Pereira, and S. Tonegawa. 1993. Gamma/delta cells. Annu. Rev. Immunol. 9:745.
27. De Libero, G., G. Casorati, C. Giachino, C. Carbonara, N. Migone, P. Matzinger, and A. Lanzavecchia. 1991. Selection by two powerful antigens may account for the presence of the major population of human peripheral γ/δ T cells. J. Exp. Med. 173:1311.
28. Constant, P., F. Davodeau, M. A. Peyrat, Y. Poquet, G. Puzo, M. Bonneville, and J. J. Fournié. 1994. Stimulation of human γδ T cells by nonpeptidic mycobacterial ligands. Science 264:287.
29. Tanaka, Y., C. T. Morita, Y. Tanaka, E. Nieves, M. B. Brenner, and B. R. Bloom. 1995. Natural and synthetic non-peptide antigens recognized by human γδ T cells. Nature 375:155.
30. Morita, C. T., E. M. Beckman, J. F. Bukowski, Y. Tanaka, H. Band, B. R. Bloom, D. E. Golan, and M. B. Brenner. 1995. Direct presentation of nonpeptidic prenyl pyrophosphate antigens to human γδ T cells. Immunity 3:495.
31. Holoshitz, J., L. M. Vila, B. J. Keroak, D. R. Mc Kinley, and N. K. Bayne. 1992. Dual antigenic recognition by cloned human γδ T cells. J. Clin. Invest. 89:308.
32. +, T lymphocytes recognize tetanus toxoid in an MHC-restricted fashion. J. Exp. Med. 169: 1847.
33. Mc Menamin, C., C. Pimm, M. Mc Kersey, and P. G. Holt. 1994. Regulation of IgE responses to inhaled antigen in mice by antigen-specific γδ T cells. Science 265:1869.
34. Mc Menamin, C. M. Mc Kersey, P. Kuhnlein, T. Hunig, and P. G. Holt. 1995. γδ T cells down-regulate primary IgE responses in rats to inhaled soluble protein antigens. J. Immunol. 154:4390.
35. Spaner, D., K. Migita, A. Ochi, J. Shannon, R. O. Miller, P. Pereira, S. Tonegawa, and R. A. Phillips. 1993. γδ T cells differentiate into a functional but nonproliferative state during a normal immune response. Proc. Natl. Acad. Sci. USA 90: 8415.
36. Kaufmann, S. H. E., C. Blum, and S. Yamamoto. 1993. Crosstalk between α/β T cells and γ/δ T cells in vivo: activation of α/β T-cell responses after γ/δ T-cell modulation with the monoclonal antibody GL3. Proc. Natl. Acad. Sci. USA 90: 9620.
37. Ferrick, F. A., M. D. Schrenzel, T. Mulvania, B. Hsieh, W. G. Ferlin, and H. Lepper. 1995. Differential production of interferon-γ and interleukin-4 in response to Th1- and Th2-stimulating pathogens by γδ T cells in vivo. Nature 373:255.
38. Pechhold, K., D. Wesch, S. Schondelmaier, and D. Kabelitz. 1994. Primary activation of Vγ9-expressing γδ T cells by Mycobacterium tuberculosis. J. Immunol. 152:4984.
39. Issekutz, T. B., J. M. Stolz, and P. Van Der Meide. 1988. Lymphocyte recruitment in delayed-type hypersensitivity: the role of IFN-γ. J. Immunol. 140:2989.
40. Nathan, C. F., G. Kaplan, W. R. Levis, A. Nuscrat, M. D. Witmer, S. A. Ierwin, C. K. Job, C. R. Horowitz, R. M. Steinman, and Z. A. Cohn. 1986. Local and systemic effect of intradermal recombinant interferon-γ in patients with lepromatous leprosy. J. Exp. Med. 115:6.
41. Martin, S. M., K. Maruta, V. Burkart, S. Gillis, and H. Kolb. 1988. IL-1 and IFN-γ increase vascular permeability. Immunology 64:301.
42. Skoglund, C., A. Scheynius, R. Holmdahl, and P. Van Der Meide. 1986. Enhancment of DTH reaction and inhibition of the expression of class II transplantation antigens by in vivo treatment with antibodies against γ-interferon. Clin. Exp. Immunol. 71:428.
43. Scott, P. 1991. IFN-gamma modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis. J. Immunol. 147:3149.
44. Finkelman, F. D., J. Holmes, I. M. Katona, M. P. Beckmann, L. S. Park, K. A. Schooley, R. L. Coffman, T. R. Mosmann, and W. E. Paul. 1990. Lymphokine control of in vivo immunoglobulin isotype selection. Annu. Rev. Immunol. 8:303.