The effect of intramural delivery of polymeric nanoparticles loaded with the antiproliferative 2-aminochromone U-86983 on neointimal hyperplasia development in balloon-injured porcine coronary arteries

Advanced Drug Delivery Reviews

Volumn 24, Issue 1, 1997, Pages 87-108

  Humphrey, William R ^a   Erickson, Laurence A ^a   Simmons, Carol A ^a   Northrup, Jennifer L ^a   Wishka, Donn G ^a   Morris, Joel ^a   Labhasetwar, Vinod ^b   Song, Cunxian ^b   Levy, Robert J ^b   Shebuski, Ronald J ^a  

^a PFIZER INC   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

Author keywords

local drug delivery; pig; polylactic polyglycolic acid; PTCA; restenosis

Indexed keywords

AGENTS; BLOOD VESSELS; CARDIOLOGY; DISEASES; DRUG PRODUCTS; EFFECTS; NANOSTRUCTURED MATERIALS; ORGANIC POLYMERS;

DIRECT INTRAMURAL DELIVERY; LOCAL DRUG DELIVERY; NEOINTIMAL HYPERPLASIA; PERCUTANEOUS TRANSLUMINAL CORONARY ANGIOPLASTY; POLYLACTIC POLYGLYCOLIC ACID; RESTENOSIS;

CONTROLLED DRUG DELIVERY;

2 AMINOCHROMONE DERIVATIVE; ANTIPROLIFERATIVE AGENT; CHROMONE DERIVATIVE; COPOLYMER; DIDODECYLDIMETHYLAMMONIUM BROMIDE; DIETHYLAMINOETHYLDEXTRAN; DIOLEOYLPHOSPHATIDYLETHANOLAMINE; DRUG CARRIER; FIBRINOGEN; FIBRONECTIN; METHYLENE BLUE; NANOPARTICLE; POLYGLACTIN; U 86983; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA PROLIFERATION; ARTERY LESION; ARTERY WALL; BALLOON DILATATION; BIODEGRADATION; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; CORONARY ARTERY OBSTRUCTION; DOG; DRUG EFFICACY; DRUG TISSUE LEVEL; DRUG UPTAKE; FEMALE; INTRAVENOUS DRUG ADMINISTRATION; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RESTENOSIS; REVIEW; SWINE; TRANSLUMINAL CORONARY ANGIOPLASTY;

EID: 0031568931     PISSN: 0169409X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-409X(96)00484-X     Document Type: Review

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